[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100518941":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":78,"collaborators":81,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":86,"sex":92,"minAge":10,"maxAge":93,"enrollmentInfo":94,"targetDuration":10,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":101,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"20 extremely low birth weight infants",null,"In addition to the standard care, all participants will be monitored using an extra oxygen saturation probe, two near infrared spectroscopy sensors, and an electrical impedance tomography belt. Data will be continuously collected from extubation to 168 hours postextubation",[13,14,15],"Device: Oxygen saturation probe","Device: Near infrared spectroscopy sensors","Device: Electrical impedance tomography",[17,22,26],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DEVICE","Oxygen saturation probe","The high-accuracy oxygen saturation signal will be continuously acquired for 168 hours post extubation from a separate pulse oximeter (Radical-7®, Masimo ROOT platform, MasimoCorp, Irvine, LA).",[9],{"type":18,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"Near infrared spectroscopy sensors","The cerebral and splanchnic regional oxygen saturation signals will be acquired continuously for 168h post extubation using two near infrared spectroscopy sensors (Masimo ROOT platform, MasimoCorp, Irvine, LA), one placed on the forehead for cerebral oxygenation and one on the abdomen (for splanchnic oxygenation).",[9],{"type":18,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Electrical impedance tomography","The regional lung ventilation will be measured using Electrical Impedance Tomography (TIMPEL, USA) at three time points:\n\n* From 1 hour pre-extubation to 2 hours post extubation (total 3 hours)\n* Between 24 and 48 hours post extubation (total 3 hours)\n* Between 72 and 96 hours post extubation (total 3 hours)",[9],[31],{"name":32,"affiliation":33,"role":34},"Wissam Shalish, MD, PhD","McGill University Health Center\u002FMontreal Children's hospital","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","+1(514) 4124452","22341","wissam.shalish@mcgill.ca",[42,62],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Centre Hospitalier Universitaire Sainte-Justine","RECRUITING","Montreal","Quebec","H3T 1C5","Canada","CA",{"type":51,"coordinates":52},"Point",[53,54],-73.58781,45.50884,{"lat":54,"lon":53},[57],{"name":58,"role":37,"phone":59,"phoneExt":60,"email":61},"Sophie Tremblay, MD, FRCPC, MSc","1-514-345-4931","4500","sophie.tremblay@umontreal.ca",{"facility":63,"status":44,"city":45,"state":46,"zip":64,"country":48,"countryCode":49,"cosmosGeoPoint":65,"geoPoint":67,"contacts":68},"McGill University Health Center","H4A 3J1",{"type":51,"coordinates":66},[53,54],{"lat":54,"lon":53},[69,71,73,76],{"name":32,"role":37,"phone":70,"phoneExt":39,"email":40},"514-412-4400",{"name":72,"role":34,"phone":10,"phoneExt":10,"email":10},"Wissam Shalish, MD PhD",{"name":74,"role":75,"phone":10,"phoneExt":10,"email":10},"Guilherme Sant'Anna, MD PhD","SUB_INVESTIGATOR",{"name":77,"role":75,"phone":10,"phoneExt":10,"email":10},"Robert E Kearney, PhD",{"type":34,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Wissam Shalish","Assistant Professor of Pediatrics, McGill University Neonatologist, Montreal Children's Hospital",[82],{"name":83,"class":6},"St. Justine's Hospital","100518941","post-extubation-assessment-of-clinical-stability-in-elbw-infants-100518941",false,"NCT06037083","Post-Extubation Assessment of Clinical Stability in ELBW Infants","Post-Extubation Assessment of Clinical Stability in Extremely Preterm Infants: The PEACE Feasibility Study","PEACE","Inclusion Criteria:\n\n* Birth weight \\\u003C 1000g and gestational age \\\u003C 28+0 weeks,\n* Received mechanical ventilation within the first 72h of life,\n* Undergoing their first planned extubation within the first 6 weeks of life.\n\nExclusion Criteria:\n\n\\- Congenital anomalies and congenital heart disorders.","ALL","28 Weeks",{"count":95,"type":96},20,"ESTIMATED","OBSERVATIONAL","This is an observational, proof-of-concept, feasibility study that aims to evaluate the feasibility of a monitoring system that integrates clinical data, high-resolution waveforms from the bedside monitor, regional oxygenation (via cerebral and splanchnic near-infrared spectroscopy), and regional ventilation (via electrical impedance tomography) from 20 extremely low birth weight infants at high-risk of reintubation.",[100],"Extremely Low Birth Weight Infants",[102,103,104,27,105,106,107,108],"Reintubation","Extubation","Extremely low birth weight infants","Cerebral and splanchnic oxygenation","Near infrared spectroscopy","apnea","intermittent hypoxia","2026-03-24",{"date":111,"type":112},"2026-03-30","ACTUAL",{"date":114,"type":112},"2024-10-29",{"date":116,"type":96},"2027-04",{"name":5,"class":6},2]