[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606389":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":11,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":11,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Laparoscopic Sacrocolpopexy","ACTIVE_COMPARATOR",null,[13],"Procedure: Laparoscopic Sacrocolpopexy",{"label":15,"type":16,"description":11,"interventionNames":17},"Laparoscopic Lateral Suspension","EXPERIMENTAL",[18],"Procedure: Laparoscopic Lateral Suspension",[20,26],{"type":21,"name":15,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Participants in this arm will undergo laparoscopic lateral suspension for post-hysterectomy vaginal cuff prolapse. The procedure involves attaching a synthetic mesh from the vaginal cuff to the lateral abdominal wall to provide support and restore normal vaginal anatomy. Standard perioperative care, including anesthesia and postoperative pain management, will be provided.",[15],[25],"Lateral Suspension (Apical Suspension)",{"type":21,"name":9,"description":27,"armGroupLabels":28,"otherNames":11},"Participants in this arm will undergo laparoscopic sacrohysteropexy for post-hysterectomy vaginal cuff prolapse. The procedure involves suspending the vaginal cuff to the sacral promontory using a synthetic mesh, restoring vaginal support. Standard perioperative care, including anesthesia and postoperative pain management, will be provided.",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Ozan Karadeniz, MD","CONTACT","+905333663003","dr.ozankrdnz@gmail.com",[36],{"facility":37,"status":38,"city":39,"state":39,"zip":40,"country":41,"countryCode":11,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Basaksehir Cam and Sakura City Hospital","RECRUITING","Istanbul","34494","Turkey (Türkiye)",{"type":43,"coordinates":44},"Point",[45,46],28.94966,41.01384,{"lat":46,"lon":45},[49],{"name":50,"role":32,"phone":51,"phoneExt":11,"email":34},"Ozan Karadeniz","05333663003",{"type":53,"investigatorFullName":50,"investigatorTitle":54,"investigatorAffiliation":55,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Principal Investigator","Başakşehir Çam & Sakura City Hospital","100606389","post-hysterectomy-vaginal-cuff-prolapse-repair-100606389",false,"NCT07174921","Post-hysterectomy Vaginal Cuff Prolapse Repair","Laparoscopic Lateral Suspension Versus Laparoscopic Sacrocolpopexy for Post-Hysterectomy Vaginal Cuff Prolapse: A Randomized Controlled Trial","Inclusion Criteria:\n\nWomen aged ≥18 years.\n\nHistory of hysterectomy (any approach: abdominal, vaginal, or laparoscopic).\n\nSymptomatic vaginal cuff prolapse (POP-Q stage ≥ II).\n\nAble to provide written informed consent.\n\nWilling and able to comply with study procedures and follow-up visits.\n\nExclusion Criteria:\n\nPrior sacrocolpopexy or lateral suspension surgery.\n\nActive pelvic infection or untreated malignancy.\n\nSevere cardiopulmonary or systemic disease that contraindicates laparoscopic surgery.\n\nKnown allergy to mesh materials used in the procedures.\n\nInability to complete patient-reported questionnaires due to cognitive or language barriers.\n\nConcurrent pelvic organ prolapse requiring additional surgical repair beyond vaginal cuff suspension.","FEMALE","18 Years",{"count":66,"type":67},50,"ESTIMATED","INTERVENTIONAL",[70],"NA","This study is a randomized controlled trial comparing two minimally invasive surgeries-laparoscopic lateral suspension and laparoscopic sacrocolporopexy-for women who develop vaginal cuff prolapse after hysterectomy. Vaginal cuff prolapse occurs when the top of the vagina loses support after the uterus is removed, which can cause discomfort, bulging, or urinary and bowel problems.\n\nThe goal of this study is to determine which surgical approach is safer, more effective, and improves quality of life for patients. Women enrolled in the trial will be randomly assigned to one of the two surgeries, and outcomes such as prolapse recurrence, complications, recovery time, and patient satisfaction will be carefully monitored.\n\nBy comparing these two techniques, this study aims to provide clear guidance for surgeons and patients to make informed decisions about the best surgical treatment for post-hysterectomy vaginal cuff prolapse.",[73],"Vaginal Cuff Complications",[75,76,77,78],"prolapse","vaginal cuff","lateral suspension","sacrocolpopexy","2025-09-13",{"date":81,"type":82},"2025-09-16","ACTUAL",{"date":84,"type":67},"2025-09-30",{"date":86,"type":67},"2026-10-15",{"name":5,"class":6},1]