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Examples of particular relevance include: immune system disorders, immunosuppressant medications of clinical relevance, bleeding disorders and unstable cardiovascular conditions, history of asthma or alpha-1 antitrypsin deficiency\n6. Newly prescribed morphine derivatives within the last 4 weeks\n7. Pregnant or breastfeeding\n8. Highly diseased lower lobes (tissue to air ratio of \\\u003C11%)\n9. Bacterial infection or symptoms indicative of active infection (i.e., fever, elevated white blood cell count)\n10. Presence of single large bulla (defined as \\> 1\u002F3 volume of lobe) or a paraseptal distribution of emphysema in the treated lobe\n11. Recent respiratory infections or COPD exacerbation in preceding 6 weeks -","ALL","18 Years",{"count":334,"type":335},300,"ESTIMATED","5 Years","OBSERVATIONAL","Bronchoscopic thermal vapor ablation using Uptake Medical Technology Inc.'s InterVapor System is indicated for treatment of patients with heterogeneous upper lobe emphysema. 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