[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605218":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":12,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":12,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":12,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":12,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":38,"whyStopped":12,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","NO_INTERVENTION","Patients in the control group will receive a standard hospital diet consistent with routine postoperative nutritional care after lobectomy with lymph node dissection. This diet does not include medium-chain triglyceride (MCT) supplementation and serves as a comparator to evaluate the effects of the MCT diet on postoperative recovery",null,{"label":14,"type":15,"description":16,"interventionNames":17},"MCT diet during hospital stay","EXPERIMENTAL","Patients will receive a medium-chain triglyceride (MCT)-enriched diet during their hospital stay following lobectomy with lymph node dissection. The MCT diet is administered as part of the postoperative nutritional regimen to evaluate its impact on recovery outcomes",[18],"Dietary Supplement: MCT Diet",{"label":20,"type":15,"description":21,"interventionNames":22},"MCT diet during hospital stay and 2 weeks after discharge","Participants will receive a medium-chain triglyceride (MCT) diet during their hospital stay and for two weeks following discharge. This aims to evaluate the effects of continued MCT dietary supplementation on postoperative recovery outcomes after lobectomy with lymph node dissection",[18],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":12},"DIETARY_SUPPLEMENT","MCT Diet","MCT diet for patients following lung resection",[14,20],[30],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},"Calvin Sze Hang Ng","CONTACT","+852 3505 2618","calvinng@surgery.cuhk.edu.hk",[36],{"facility":37,"status":38,"city":39,"state":12,"zip":12,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Prince of Wales Hospital","RECRUITING","Shatin","Hong Kong","HK",{"type":43,"coordinates":44},"Point",[45,46],114.18333,22.38333,{"lat":46,"lon":45},[49],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},{"type":51,"investigatorFullName":31,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Professor","100605218","post-operative-medium-chain-triglyceride-diet-may-reduce-hospital-stay-following-lung-resection-100605218",false,"NCT07159659","Post-operative Medium Chain Triglyceride Diet May Reduce Hospital Stay Following Lung Resection","Inclusion Criteria:\n\nGeneral Inclusion Criteria for All procedures:\n\n1. Age between 18 - 80 years\n2. Body mass index \\\u003C35 kg\u002Fm2\n3. Suitable for minimally invasive surgery\n4. Willingness to participate as demonstrated by giving informed consent\n\nProject-specific Criteria:\n\n1\\. Patients performed lobectomy with lymph node dissection\n\nExclusion Criteria:\n\nPatient general exclusion criteria:\n\n1. Contraindication to general anesthesia\n2. Severe concomitant illness that drastically shortens life expectancy or increases the risk of therapeutic intervention\n3. Untreated active infection\n4. Non-correctable coagulopathy\n5. Emergency surgery\n6. Vulnerable population (e.g. mentally disabled, pregnancy)\n\nProject-specific Criteria\n\n1. Segmentectomy\n2. Pleurodesis\n3. Esophageal procedures\n4. Redo\u002Freadmitted patients for lung resection\n5. Chylothorax (Triglyceride \\> 110 mL, excluded at day 1 routine lab check)\n6. Air leak (\\> 30 mL\u002Fmin when back to ward)\n7. Heart Failure\n8. Renal failure (estimated GFR \\\u003C 30; CKD grading stage 4-5)\n9. Moderate to severe adhesion (defined at randomization by surgeon; criteria include estimated surface area of adhesion and staging)\n10. History of tuberculosis or empyema","ALL","18 Years","80 Years",{"count":63,"type":64},210,"ESTIMATED","INTERVENTIONAL",[67],"NA","Lung resection, a critical treatment for various thoracic diseases, including lung cancer, often necessitates prolonged hospitalization due to rare but severe postoperative complications such as chyle leaks, with an occurrence of 0.25%-3%, prolonging chest drainage, and delaying recovery. Therefore, effective postoperative care is essential for optimizing outcomes, reducing complications, and expediting recovery.\n\nRecent studies have highlighted the significant potential of medium-chain triglyceride (MCT) diets, owing to their unique absorption pathway and metabolic properties. MCT contains mainly medium-chain fatty acids (MCFA), which is absorbed in the intestine and transported to the liver via the portal system instead of the lymphatic system. This helps to bypass the lymphatic system, thereby reducing the volume of lymph. MCFAs also provide better energy utilization in stressed condition since it does not require carnitine shuttle upon metabolism, which is beneficial to post-operation recovery.\n\nSeveral studies have demonstrated the benefits of MCT diets in managing chyle leaks and supporting gastrointestinal recovery, particularly in conditions that strain the lymphatic system. For instance, short-term MCT-enriched diets have been associated with improved post-operation recovery of gastrointestinal, hepatic and renal functions, reduced total chest drainage volumes, and shorter hospital stay when compared to regular diet groups.\n\nPatients with post-operative chyle leak following thoracic surgery are often given an MCT diet to reduce chest drain volume and hence shorten hospital stay. Based on the successful use of MCT diet on patients with chyle leak after lobectomy, it is hypothesized that patients with chylothorax provided with post-operative MCT diet can also shorten hospital stay by decreasing chest drainage. Therefore, a prospective and randomized trial is designed to investigate how post-operative MCT diet in lung resection patients without chylothorax may affect hospital stay and post-operative recovery.",[70],"Thoracic Neoplasms",[72,73,74],"Medium Chain Triglyceride Diet","Lung Resection","Video-assisted thoracoscopic surgery","2026-03-18",{"date":77,"type":78},"2026-03-20","ACTUAL",{"date":80,"type":64},"2026-03-19",{"date":82,"type":64},"2027-08-30",{"name":5,"class":6},1]