[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528921":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":159,"collaborators":26,"id":162,"slug":163,"hasResults":164,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":26,"eligibilityCriteria":168,"healthyVolunteers":164,"sex":169,"minAge":170,"maxAge":26,"enrollmentInfo":171,"targetDuration":26,"studyType":174,"phases":175,"briefSummary":177,"conditions":178,"keywords":180,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":193},{"fullName":5,"class":6},"Carmel Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"A","EXPERIMENTAL","Single post-operative MMC 40mg or gemcitabine 2gr in Saline 0.9% 50cc bladder instillation",[13],"Drug: Mitomycin\u002FGemcitabine",{"label":15,"type":16,"description":17,"interventionNames":18},"B","PLACEBO_COMPARATOR","Single post-operative 50cc Saline 0.9% bladder instillation",[19],"Drug: Saline",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Mitomycin\u002FGemcitabine","UTUC treatment",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Saline",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Yuval Freifeld, Dr","CONTACT","+972-4-8250843","yuvalfr@clalit.org.il",[37,53,65,77,90,101,110,123,135,147],{"facility":38,"status":39,"city":40,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Assuta Ashdod Hospital","RECRUITING","Ashdod","Israel","IL",{"type":44,"coordinates":45},"Point",[46,47],34.64966,31.79213,{"lat":47,"lon":46},[50],{"name":51,"role":33,"phone":26,"phoneExt":26,"email":52},"Dor Golomb, Dr","golombdor@gmail.com",{"facility":54,"status":39,"city":55,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Soroka University Medical Center","Beersheba",{"type":44,"coordinates":57},[58,59],34.7913,31.25181,{"lat":59,"lon":58},[62],{"name":63,"role":33,"phone":26,"phoneExt":26,"email":64},"Jonathan Wagmaister, Dr","jonathanwa@clalit.org.il",{"facility":66,"status":39,"city":67,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Shamir Medical Center","Be’er Ya‘aqov",{"type":44,"coordinates":69},[70,71],34.83749,31.93864,{"lat":71,"lon":70},[74],{"name":75,"role":33,"phone":26,"phoneExt":26,"email":76},"Amnon Zisman, Prof","AmnonZ@shamir.gov.il",{"facility":78,"status":39,"city":79,"state":26,"zip":80,"country":41,"countryCode":42,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Bnai Zion Medical Center","Haifa","31048",{"type":44,"coordinates":82},[83,84],34.99928,32.81303,{"lat":84,"lon":83},[87],{"name":88,"role":33,"phone":26,"phoneExt":26,"email":89},"Zaher Bahouth, Dr","zaher.bahouth@gmail.com",{"facility":5,"status":39,"city":79,"state":26,"zip":91,"country":41,"countryCode":42,"cosmosGeoPoint":92,"geoPoint":94,"contacts":95},"34362",{"type":44,"coordinates":93},[83,84],{"lat":84,"lon":83},[96,99],{"name":97,"role":33,"phone":26,"phoneExt":26,"email":98},"Yuval Freifeld, Dr.","Yuvalfr@clalit.org.il",{"name":97,"role":100,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"facility":102,"status":39,"city":79,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":103,"geoPoint":105,"contacts":106},"Rambam Health Care Campus",{"type":44,"coordinates":104},[83,84],{"lat":84,"lon":83},[107],{"name":108,"role":33,"phone":26,"phoneExt":26,"email":109},"Michael Mullerad, Dr","M_MULLERAD@rambam.health.gov.il",{"facility":111,"status":39,"city":112,"state":26,"zip":113,"country":41,"countryCode":42,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Rabin Medical Center - Beilinson and Hasharon","Petah Tikva","4937211",{"type":44,"coordinates":115},[116,117],34.88747,32.08707,{"lat":117,"lon":116},[120],{"name":121,"role":33,"phone":26,"phoneExt":26,"email":122},"David Lifshitz, Prof","davidlif@clalit.org.il",{"facility":124,"status":39,"city":125,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"Kaplan Medical Center","Rehovot",{"type":44,"coordinates":127},[128,129],34.81199,31.89421,{"lat":129,"lon":128},[132],{"name":133,"role":33,"phone":26,"phoneExt":26,"email":134},"Yaniv Shilo, Dr","MRYANIVSH@clalit.org.il",{"facility":136,"status":39,"city":137,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":138,"geoPoint":142,"contacts":143},"Ziv Medical Center","Safed",{"type":44,"coordinates":139},[140,141],35.496,32.96465,{"lat":141,"lon":140},[144],{"name":145,"role":33,"phone":26,"phoneExt":26,"email":146},"Ran Katz, Dr","rank@ziv.gov.il",{"facility":148,"status":39,"city":149,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":150,"geoPoint":154,"contacts":155},"Tel Aviv Sourasky Medical Center - Ichilov","Tel Aviv",{"type":44,"coordinates":151},[152,153],34.78057,32.08088,{"lat":153,"lon":152},[156],{"name":157,"role":33,"phone":26,"phoneExt":26,"email":158},"Ziv Savin, Dr","zivsavin23@gmail.com",{"type":100,"investigatorFullName":160,"investigatorTitle":161,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Yuval Freifeld","Head of Urologic-Oncology unit, Carmel Medical Center","100528921","post-urs-chemotherapy-instillation-100528921",false,"NCT06167057","POST URS Chemotherapy Instillation","Single Bladder Instillation With Chemotherapy Following Endoscopic Treatment for Upper Tract Urothelial Carcinoma to Reduce Bladder Recurrence","Inclusion Criteria:\n\n* Radiographic and\u002For cytological suspicion for UTUC\n* Planned endoscopic procedure for treatment \u002F diagnosis of UTUC\n* Patients with bladder cancer history are eligible if meeting both following criteria:\n\nNo recurrence within the last two years Are not on active bladder irrigation protocol\n\n* Patients with history of UTUC are eligible if last endoscopic treatment or RNU was \\>1 year prior to enrollment\n* Age ≥ 18 years\n* Performance status ECOG 0-2\n\nExclusion Criteria:\n\n* Subjects who have had bladder \u002F prostate radiotherapy\n* Subjects with bladder cancer history on active bladder irrigation protocols or with active disease within two years prior to enrollment\n* Subjects with previously treated UTUC within one year prior to enrollment\n* Subjects with metastatic disease","ALL","18 Years",{"count":172,"type":173},264,"ESTIMATED","INTERVENTIONAL",[176],"NA","The goal of this study is to evaluate the safety and oncological outcomes of single chemotherapy bladder instillation following endoscopic treatment for UTUC in UTUC suspected patients .The main aim is to determine the efficacy of a single, post URS, chemotherapy bladder instillation to reduce IVR.\n\nParticipants will be given single chemotherapy bladder instillation within 24h following ureteroscopy and will follow routine follow-up for IVR which will include white light cystoscopy ;patients with suspected IVR (based on either imaging or cystoscopy) will undergo TURBT.",[179],"UTUC",[181,182,183],"diagnostic URS","single-dose chemotherapy bladder instillation","IVR","2023-12-14",{"date":186,"type":187},"2023-12-20","ACTUAL",{"date":189,"type":187},"2023-04-17",{"date":191,"type":173},"2028-01-30",{"name":5,"class":6},10]