[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620554":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":38,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":10,"overallStatus":59,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Group 1 - Platelet-Rich Plasma injection therapy group",null,"Patients who received Platelet-Rich Plasma injections during surgery.",{"label":13,"type":10,"description":14,"interventionNames":10},"Group 2 - Platelet-Rich Fibrin injection therapy group","Patients who are receiving Platelet-Rich Fibrin injections during surgery.",{"label":16,"type":10,"description":17,"interventionNames":10},"Group 3 - non injection therapy group","Patients who are not receiving Platelet-Rich Plasma nor Platelet-Rich Fibrin injections during surgery.",[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Jingping Wang, MD PhD","CONTACT","6179369136","jwang23@mgh.harvard.edu",[25],{"facility":26,"status":10,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"Meikun Wang","Boston","Massachusetts","02114","United States","US",{"type":33,"coordinates":34},"Point",[35,36],-71.05977,42.35843,{"lat":36,"lon":35},{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Jingping Wang, MD, Ph.D.","Associate Professor Staff Anesthesiologist & Pain Physician","100620554","postoperative-assessment-of-platelet-rich-plasma-and-platelet-rich-fibrin-in-temporomandibular-joint-surgery-100620554",false,"NCT07359131","Postoperative Assessment of Platelet-Rich Plasma and Platelet-Rich Fibrin in Temporomandibular Joint Surgery","Postoperative Assessment in TMJ Surgery: A Comparison of the Efficacy of Intraoperative Platelet-Rich Plasma and Platelet-Rich Fibrin Injections","Inclusion Criteria:\n\nPatients aged 18 to 75 years (inclusive)\n\nUnderwent unilateral or bilateral temporomandibular joint (TMJ) arthroscopy\n\nReceived intraoperative platelet-rich plasma (PRP) or platelet-rich fibrin (PRF) injection during TMJ arthroscopy\n\nExclusion Criteria:\n\nAge younger than 18 years or older than 75 years\n\nDid not undergo TMJ arthroscopy\n\nDid not receive intraoperative PRP or PRF injection\n\nIncomplete clinical or follow-up data","ALL","18 Years","75 Years",{"count":53,"type":54},700,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate postoperative outcomes following temporomandibular joint (TMJ) surgery and to compare the effectiveness of intraoperative platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) injections in patients with temporomandibular joint disorders.\n\nThe study includes adult patients who underwent TMJ surgery and received either PRP or PRF intraoperatively. The main questions this study aims to answer are:\n\nWhether intraoperative PRP or PRF injection is associated with differences in postoperative pain intensity and recovery.\n\nWhether PRP and PRF differ in their effects on postoperative jaw function, including maximum mouth opening and joint symptoms.\n\nIf there is a comparison group: Researchers will compare patients who received intraoperative PRP with those who received intraoperative PRF to assess differences in postoperative pain, functional outcomes, and joint-related symptoms.\n\nParticipants will:\n\nHave their existing medical records reviewed retrospectively.\n\nProvide postoperative outcome data derived from routine clinical follow-up, with no prospective recruitment or intervention.",[58],"Temporomandibular Joint Disorders","NOT_YET_RECRUITING","2026-06-06",{"date":62,"type":63},"2026-06-09","ACTUAL",{"date":65,"type":54},"2026-11-15",{"date":67,"type":54},"2027-12-05",{"name":40,"class":6},1]