[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565160":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":37,"responsibleParty":54,"collaborators":58,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":18,"enrollmentInfo":71,"targetDuration":18,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":40,"whyStopped":18,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Basal Bolus","EXPERIMENTAL","Patients daily dose of insulin is calculated by their treatment team: In insulin naive patients 0.4-0.5IU\u002Fkg and 0,3IU\u002Fkg for patients aged\\>70 or patients with impaired kidney function with an estimated glucose filtration rate \\\u003C60ml\u002Fmin and 80-100% of own insulin for insulin-users. They receive half of this daily dose in long-acting insulin once a day. The other half of their total daily dose of insulin is provided as short-acting mealtime insulin. This short-acting insulin is administered before each meal. When needed, extra insulin can be given when needed.\n\nThe measurements of blood glucose values are before each meal and at bedtime (4x\u002Fday).",[13],"Other: Basal bolus insulin regimen",{"label":15,"type":16,"description":17,"interventionNames":18},"Sliding Scale","NO_INTERVENTION","Short-acting insulin is administered when blood glucose value is above 10,0 mmol\u002FL according to a standardized dosage schedule. The measurements of blood glucose values are before each meal and at bedtime (4x\u002Fday).",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Basal bolus insulin regimen","Combination of long-acting and short-acting insulin in a proactive schedule for achieving better blood glucose values postoperatively",[9],[25],{"name":26,"affiliation":27,"role":28},"Sarah E. Siegelaar, MD, PhD","Amsterdam UMC, location AMC","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Ayla Y. Stobbe, MD","CONTACT","0031205669111","a.y.stobbe@amsterdamumc.nl",{"name":26,"role":32,"phone":33,"phoneExt":18,"email":36},"s.e.siegelaar@amsterdamumc.nl",[38],{"facility":39,"status":40,"city":41,"state":18,"zip":18,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Amsterdam UMC","RECRUITING","Amsterdam","Netherlands","NL",{"type":45,"coordinates":46},"Point",[47,48],4.88969,52.37403,{"lat":48,"lon":47},[51],{"name":31,"role":32,"phone":52,"phoneExt":18,"email":53},"020-5669111","guide_research@amsterdamumc.nl",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Abraham Hulst, MD, PhD","Clinical investigator, anesthesiologist",[59],{"name":60,"class":6},"ZonMw: The Netherlands Organisation for Health Research and Development","100565160","postoperative-basal-bolus-or-sliding-scale-insulin-regimen-in-dm2-and-its-effect-on-surgical-site-infections-100565160",false,"NCT06638567","Postoperative Basal Bolus or Sliding Scale Insulin Regimen in DM2 and Its Effect on Surgical Site Infections.","Postoperative Glucose Control with a Basal Bolus Versus Sliding Scale Insulin Regimen and Its Effect on the Incidence of Surgical Site Infections in People with Type 2 Diabetes Mellitus.","GUIDE","Inclusion Criteria:\n\n* Patients aged 18 or older\n* Diagnosed with type 2 diabetes mellitus\n* Undergoing gastointestinal or vascular surgery\n* Admitted to one of the participating surgical wards\n* Expected duration of stay at least one overnight stay\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Diagnosed with type 1 diabetes mellitus\n* Female of child-bearing potential who is pregnant or breastfeeding.\n* Undergoing complete pancreatectomy\n* Undergoing bariatric surgery\n* Patients using a continuous insulin pump at home\n* Patients undergoing a necrotectomy\u002Fwound debridement from a pre-existent wound.","ALL","18 Years",{"count":72,"type":73},1008,"ESTIMATED","INTERVENTIONAL",[76],"NA","A multicentre, matched-pair, cluster randomised controlled superiority trial to investigate the effect of a proactive basal bolus insulin regimen compared to the reactive sliding scale insulin regimen, targeting a glucose level of 3.9-10.0 mmol\u002FL, to reduce the number of surgical site infections within the first 30 days postoperatively in adult patients with diabetes mellitus type 2.",[79,80],"Diabetes Mellitus, Type 2","Surgical Site Infection",[82,83,84,85,86],"Diabetes Mellitus","Basal bolus regimen","Surgical site infections","Sliding scale","Insulin regimen","2025-01-28",{"date":89,"type":90},"2025-01-30","ACTUAL",{"date":92,"type":90},"2025-01-03",{"date":94,"type":73},"2027-09",{"name":56,"class":6},1]