[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623146":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":10,"responsibleParty":29,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":10,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":10,"enrollmentInfo":41,"targetDuration":10,"studyType":44,"phases":10,"briefSummary":45,"conditions":46,"keywords":10,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":10},{"fullName":5,"class":6},"Minia University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group A",null,"25 patients with preoperative sleep disorders",{"label":13,"type":10,"description":14,"interventionNames":10},"Group B","25 patients without preoperative sleep disorders",[16],{"name":17,"affiliation":18,"role":19},"Mohamed Mostafa Ali, MD","El-minya University Hospital","PRINCIPAL_INVESTIGATOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Mohamed Yasein Mohamed, Assistant lecturer","CONTACT","+20 01016383701","myasein76@yahoo.com",{"name":17,"role":23,"phone":27,"phoneExt":10,"email":28},"+201009650970","drzahrawy3@gmail.com",{"type":19,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mohamed Yasein Mohamed Moawad","Principal investigator, assistant lecturer anesthesiologist","100623146","postoperative-cognitive-dysfunction-in-elderly-and-its-relation-with-sleep-disorders-and-melanin-concentrating-hormone-100623146",false,"NCT07392840","Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentrating Hormone","Postoperative Delayed Neurocognitive Recovery in Elderly Patients Undergoing Spinal Anesthesia: Assessment of Its Prevalence and Correlation With Preoperative Sleep Disorders and Melanin Concentrating Hormone.","Inclusion Criteria:\n\n* Patients of both genders ageing 65 years or above.\n* ASA grade I to III.\n* Undergo elective lower limb surgery under spinal anesthesia\n* Agree to collect one's own CSF and blood samples\n\nExclusion Criteria:\n\n* Past history of depression,anxiety,delirium and schizophrenia .\n* Past history of drug dependence.\n* Past history of dementia,including Alzheimer disease(AD).\n* Preoperative Montreal Cognitive Assessment (MoCA) score \\\u003C26.\n* Inability to understand or cooperate with the evaluation scale or questionnaire.\n* Refuse collecting one's own CSF and blood samples.","ALL","65 Years",{"count":42,"type":43},50,"ESTIMATED","OBSERVATIONAL","The aim of this study is to explore the relationship between preoperative sleep disorders, melanin-concentrating hormone (MCH), and delayed neurocognitive recovery early after surgery in older adult patients undergoing spinal anesthesia.",[47],"Postoperative Cognitive Dysfunction","NOT_YET_RECRUITING","2026-02-06",{"date":51,"type":52},"2026-02-10","ACTUAL",{"date":54,"type":43},"2026-02-01",{"date":56,"type":43},"2027-04-01",{"name":5,"class":6}]