[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616775":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":112,"collaborators":115,"id":125,"slug":126,"hasResults":127,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":10,"eligibilityCriteria":130,"healthyVolunteers":127,"sex":131,"minAge":132,"maxAge":133,"enrollmentInfo":134,"targetDuration":10,"studyType":137,"phases":10,"briefSummary":138,"conditions":139,"keywords":145,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":156},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Low Pa02 Group",null,"Patients were defined as belonging to the Low PaO₂ group if they exhibited at least one recorded instance of PaO₂ \\\u003C80 mmHg within the first postoperative week.",{"label":13,"type":10,"description":14,"interventionNames":10},"Normal PaO2 Group","Patients maintained a PaO₂ ≥80 mmHg throughout the first postoperative week.",[16],{"name":17,"affiliation":18,"role":19},"Hong Yang, M.D.","Department of Thoracic Surgery, Sun Yat-sen University Cancer Center","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","8613560405144","yanghong@sysucc.org.cn",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Yizhang Chen, M.D. candidate","8613533718832","chenyizhang@sysucc.org.cn",[30,45,58,72,86,100],{"facility":18,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Guangzhou","Guangdong","510060","China","CN",{"type":38,"coordinates":39},"Point",[40,41],113.25,23.11667,{"lat":41,"lon":40},[44],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},{"facility":46,"status":31,"city":47,"state":33,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":48,"geoPoint":52,"contacts":53},"Cancer Hospital of Shantou University Medical College","Shantou",{"type":38,"coordinates":49},[50,51],116.67876,23.35489,{"lat":51,"lon":50},[54],{"name":55,"role":22,"phone":56,"phoneExt":10,"email":57},"Shaobin Li, MD","0754 8855 5844","chensb535176@hotmail.com",{"facility":59,"status":31,"city":60,"state":61,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital","Shijiazhuang","Hebei",{"type":38,"coordinates":63},[64,65],114.47861,38.04139,{"lat":65,"lon":64},[68],{"name":69,"role":22,"phone":70,"phoneExt":10,"email":71},"Xinjian Xu, MD","0311-86095588","syxuxinjian0799@hebmu.edu.cn",{"facility":73,"status":31,"city":74,"state":75,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Shanghai Chest Hospital","Shanghai","Shanghai Municipality",{"type":38,"coordinates":77},[78,79],121.45806,31.22222,{"lat":79,"lon":78},[82],{"name":83,"role":22,"phone":84,"phoneExt":10,"email":85},"Zhigang Li, MD","021-22200000","zhigang.li@shsmu.edu.cn",{"facility":87,"status":31,"city":88,"state":89,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Sichuan Cancer Hospital","Chengdu","Sichuan",{"type":38,"coordinates":91},[92,93],104.06667,30.66667,{"lat":93,"lon":92},[96],{"name":97,"role":22,"phone":98,"phoneExt":10,"email":99},"Xuefeng Leng, MD","028 8542 0305","leng724@163.com",{"facility":101,"status":31,"city":102,"state":89,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"0817-2598459","Nanchong",{"type":38,"coordinates":104},[105,106],106.08473,30.79508,{"lat":106,"lon":105},[109],{"name":110,"role":22,"phone":10,"phoneExt":10,"email":111},"Hao Yang, MD","501912904@qq.com",{"type":19,"investigatorFullName":113,"investigatorTitle":114,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Yang Hong","Professor",[116,118,120,122,124],{"name":117,"class":6},"Sichuan Cancer Hospital and Research Institute",{"name":119,"class":6},"Affiliated Hospital of North Sichuan Medical College",{"name":121,"class":6},"Hebei Medical University Fourth Hospital",{"name":123,"class":6},"Affiliated Cancer Hospital of Shantou University Medical College",{"name":73,"class":6},"100616775","postoperative-hypoxemia-increases-the-risk-of-anastomotic-leak-after-radical-esophagectomy-100616775",false,"NCT07309991","Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy","Inclusion Criteria:\n\n* Patients diagnosed with esophageal carcinoma or benign esophageal tumors\n* Patients requiring surgical resection of the lesion with subsequent esophageal reconstruction\n* Patients must have had at least one postoperative arterial blood gas analysis\n* Patients must have routinely undergone at least one of the following for postoperative evaluation of the anastomosis: endoscopy, CT scan, or esophagram\n\nExclusion Criteria:\n\n* Patients who did not require esophageal reconstruction\n* Patients undergoing esophageal replacement with colon\n* Patients with incomplete data","ALL","18 Years","80 Years",{"count":135,"type":136},2500,"ESTIMATED","OBSERVATIONAL","This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\\\u003C80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. The investigators conducted a retrospective analysis of cases from their center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.",[140,141,142,143,144],"Esophageal Carcinoma","Esophageal Adenocarcinoma","Esophagectomy","PaO2","Esophageal Anastomotic Leakeage",[146],"Effect of Postoperative PaO₂ on Anastomotic Leakage Following Esophagectomy","2026-06-13",{"date":149,"type":150},"2026-06-16","ACTUAL",{"date":152,"type":150},"2021-01-01",{"date":154,"type":136},"2026-12-01",{"name":5,"class":6},6]