[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556704":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":48,"centralContacts":52,"locations":61,"responsibleParty":80,"collaborators":35,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":35,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":35,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":35,"overallStatus":63,"whyStopped":35,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Cleveland Dental Institute","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Conventional root canal treatment","ACTIVE_COMPARATOR","Irrigation will be performed with side vented needles only",[13],"Device: Conventional root canal treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Irrigant activation with Ultrasonic","EXPERIMENTAL","Final irrigant activation will be done by ultrasonic",[19],"Device: Ultrasonic",{"label":21,"type":16,"description":22,"interventionNames":23},"Irrigant activation with negative pressure","Final irrigant activation will be performed with apical negative pressure",[24],"Device: Apical negative pressure",{"label":26,"type":16,"description":27,"interventionNames":28},"Irrigant activation with both Ultrasonic and negative pressure","Final irrigation with a combination of ultrasonic and apical negative pressure using the IVAC device.",[29],"Device: Combined Ultrasonic and negative pressure",[31,36,40,44],{"type":32,"name":9,"description":33,"armGroupLabels":34,"otherNames":35},"DEVICE","Root canals will be irrigated by only side perforated needle",[9],null,{"type":32,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Ultrasonic","Root canals will finally receive activation of the irrigant by the ultrasonic part of the IVAC system",[15],{"type":32,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"Apical negative pressure","Root canals will finally receive activation of the irrigant by the negative pressure part of the IVAC system",[21],{"type":32,"name":45,"description":46,"armGroupLabels":47,"otherNames":35},"Combined Ultrasonic and negative pressure","Root canals will finally receive activation of the irrigant by the IVAC system which is a combination of ultrasonic and apical negative pressure procedures.",[26],[49],{"name":50,"affiliation":5,"role":51},"Ahmed A Hashem, PhD","STUDY_CHAIR",[53,57],{"name":50,"role":54,"phone":55,"phoneExt":35,"email":56},"CONTACT","4405021591","a.hashem@cdiohio.org",{"name":58,"role":54,"phone":59,"phoneExt":35,"email":60},"Waleed Elmallah, PhD","2163336695","w.elmallah@cdiohio.org",[62],{"facility":5,"status":63,"city":64,"state":65,"zip":66,"country":67,"countryCode":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"RECRUITING","Cleveland","Ohio","44128","United States","US",{"type":70,"coordinates":71},"Point",[72,73],-81.69541,41.4995,{"lat":73,"lon":72},[76,78],{"name":50,"role":54,"phone":77,"phoneExt":35,"email":56},"440-502-1591",{"name":79,"role":54,"phone":59,"phoneExt":35,"email":60},"Waleed Elmallah",{"type":81,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100556704","postoperative-pain-after-activation-of-irrigant-100556704",false,"NCT06528574","Postoperative Pain After Activation of Irrigant","Incidence of Postoperative Pain After Activation of Irrigant With Apical Negative Pressure and Ultrasonics in Mandibular Molar Teeth With Irreversible Pulpitis: A Randomized Controlled Trial","Inclusion Criteria:\n\nMales and females Age :20-50 Mandibular mature first molars with symptomatic acute pulpitis Medically free patients\n\nExclusion Criteria:\n\nPulp necrosis or apical periodontitis Periodontal disease Vertical root fracture Radiographic apical radiolucency\n\n\\-",true,"ALL","18 Years","50 Years",{"count":94,"type":95},84,"ESTIMATED","INTERVENTIONAL",[98],"NA","The purpose of this research is to analyze the levels of pain after cleaning and shaping in individuals who are receiving root canal therapy using the IVAC irrigation approach, and those who are treated with ultrasonic irrigation techniques, negative pressure irrigation technique and traditional irrigation techniques.\n\nPICOTS Question:\n\nDoes the new Dent's iVac irrigation protocol has an effect on reduction of postoperative pain\n\nBy enlisting at least 84 suitable individuals who are undergoing the identical endodontic procedure.\n\npain will be measures by assessing pain levels through a standardized numerical rate scale (NRS) at certain time intervals after root canal treatment, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours.",[101],"Pain","2024-07-26",{"date":104,"type":105},"2024-07-30","ACTUAL",{"date":107,"type":105},"2023-08-01",{"date":109,"type":95},"2025-04-30",{"name":5,"class":6},1]