[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624526":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":25,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":25,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"HITEC-Institute of Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bioceramic Sealer Group","EXPERIMENTAL","Participants in this group will receive root canal obturation using bioceramic (calcium silicate-based) sealer (CeraSeal) following standard endodontic procedures. After proper anesthesia and rubber dam isolation, the canals will be prepared, irrigated, and dried. A single-cone obturation technique will be used to place the sealer and gutta-percha. The cavities will be sealed with glass ionomer cement, and patients will record postoperative pain using the Visual Analog Scale (VAS) at 12, 24, 48, and 72 hours.",[13],"Procedure: CeraSeal Bioceramic Sealer",{"label":15,"type":10,"description":16,"interventionNames":17},"Calcium Hydroxide Sealer","Participants in this group will receive root canal obturation using calcium hydroxide-based sealer (Sealapex) following the same standard endodontic procedures as Arm 1. Postoperative pain will be measured using the VAS at 12, 24, 48, and 72 hours.",[18],"Procedure: Sealapex Calcium Hydroxide Sealer",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","CeraSeal Bioceramic Sealer","Participants will receive root canal obturation using CeraSeal Bioceramic Sealer. The sealer will be applied with a matching-taper gutta-percha cone using the single-cone technique after standard canal preparation and irrigation. The cavity will be sealed with glass ionomer cement. Postoperative pain will be recorded by participants using a Visual Analog Scale (VAS) at 12, 24, 48, and 72 hours.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sealapex Calcium Hydroxide Sealer","Participants will receive root canal obturation using Sealapex Calcium Hydroxide Sealer applied with a matching-taper gutta-percha cone using the single-cone technique after standard canal preparation and irrigation. Cavities will be sealed with glass ionomer cement. Postoperative pain will be recorded by participants using the VAS at 12, 24, 48, and 72 hours.",[15],[31],{"name":32,"affiliation":33,"role":34},"Monal Fatima","HITEC-IMS, Department of Operative Dentistry, Taxila, Pakistan","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Monal Fatima, BDS","CONTACT","03004410676","manalfatima1100@gmail.com",{"name":42,"role":38,"phone":43,"phoneExt":25,"email":25},"Beenish Qureshi, BDS, FCPS","+92 333 4368332",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Department of Operative Dentistry, HITEC-IMS Dental College","RECRUITING","Rawalpindi","Punjab Province","Pakistan","PK",{"type":53,"coordinates":54},"Point",[55,56],73.0479,33.59733,{"lat":56,"lon":55},[59,60],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},{"name":42,"role":38,"phone":43,"phoneExt":25,"email":25},{"type":34,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"monal fatima","FCPS Part II Trainee, Operative Dentistry and Endodontics","100624526","postoperative-pain-after-root-canal-obturation-using-bioceramic-and-calcium-hydroxide-sealers-100624526",false,"NCT07410780","Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers","Assessment of Postoperative Pain in Patients Obturated With Bioceramic and Calcium Hydroxide Sealers: A Randomized Clinical Trial","BCvsCaOH","Inclusion Criteria:\n\n* Patients aged 18-40 years\n* Single-rooted permanent teeth\n* Teeth diagnosed with symptomatic irreversible pulpitis\n* Normal periapical condition on radiographic examination or periodontal ligament (PDL) space widening\n* Restorable teeth\n\nExclusion Criteria:\n\n* Patients with systemic conditions that could alter the course of treatment\n* Teeth with immature root development\n* Teeth with necrotic pulp\n* Teeth exhibiting root resorption\n* Teeth with calcified root canals","ALL","18 Years","40 Years",{"count":76,"type":77},50,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study is designed to find out how different root canal sealers affect pain after root canal treatment. We are comparing two types of dental sealers: bioceramic sealer and calcium hydroxide sealer.\n\nParticipants who need root canal treatment will receive one of these sealers as part of their standard dental care. After the procedure, they will be asked to report any pain they experience for a few days.\n\nThe information from this study will help dentists choose sealers that may reduce post-treatment pain and improve patient comfort after root canal therapy.",[83],"Symptomatic Irreversible Pulpitis","2026-02-13",{"date":86,"type":87},"2026-02-17","ACTUAL",{"date":89,"type":87},"2026-01-01",{"date":91,"type":77},"2026-12-01",{"name":5,"class":6},1]