[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598452":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":25,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":25,"maxAge":25,"enrollmentInfo":48,"targetDuration":25,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":67,"whyStopped":25,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":25},{"fullName":5,"class":6},"Minia University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Calcium Hydroxide Group (GROUP I)","EXPERIMENTAL","Treated using calcium hydroxide as an intracanal medicament (n=28)",[13],"Drug: Calcium Hydroxide Intracanal medication",{"label":15,"type":10,"description":16,"interventionNames":17},"Bioceramic Group (GROUP II)","treated using bio-ceramic based material as an intracanal medicament (n=28)",[18],"Drug: bioceramic based intracanal medication",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Calcium Hydroxide Intracanal medication","Treated using calcium hydroxide based material as an intracanal medicament",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"bioceramic based intracanal medication","treated using bio-ceramic based material as an intracanal medicament",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Abdulrahman Issam Marie","CONTACT","+201069060274","mr.marie98@gmail.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Abdulrahman Issam Abdulkareem Marie","Postgraduate Student, Department of Endodontics","100598452","postoperative-pain-and-flare-up-rates-in-diabetic-type-ii-patients-following-the-use-of-bioceramic-intracanal-medication-100598452",false,"NCT07071675","Postoperative Pain and Flare-Up Rates in Diabetic Type II Patients Following The Use of Bioceramic Intracanal Medication","Postoperative Pain and Flare-Up Incidence Following the Use of Bio Ceramic Based Intra-Canal Medication in Diabetic Type II Patients (A Randomized Clinical Trial)","Inclusion Criteria:\n\n* Patients with controlled diabetes mellitus type II.\n* Necrotic single rooted teeth:\n\n  * with periapical lesion ranging (1-2mm) in diameter.\n  * with complete root formation.\n  * Without calcified root canals.\n  * Without root caries.\n  * Without external or internal root resorption.\n  * Without anatomical abnormalities such as fusion.\n\nExclusion Criteria:\n\n* Pregnant females.\n* Patients with other systemic diseases in combination with diabetes mellitus.\n* Patients under antibiotic or analgesic administration.\n* Patients with facial swelling.\n* Teeth that are not indicated for endodontic treatment: bad oral hygiene, mobile teeth, or recessed teeth.\n* Previously endodontically treated teeth.\n* Teeth with sinus tract.","ALL",{"count":49,"type":50},56,"ESTIMATED","INTERVENTIONAL",[53],"NA","The goal of this randomized clinical trial is to evaluate the Postoperative Pain and Flare-Up incidence following the use of Bio-Ceramic Based Intra-Canal Medication in Diabetic type II Patients compared to the Calcium Hydroxide based Intra-canal medicament.\n\nThe main questions it aims to answer are:\n\n1. Is there any difference between using the two intracanal medicaments in the aspects of postoperative pain and flare-up incidence in diabetic type II patients?\n2. Do intracanal medications reduce postoperative pain and flare-up incidence in diabetic type II patients?\n\nParticipants will be divided into two groups:\n\n( both groups will receive root canal treatment in single rooted teeth) then: First group: will receive \"Calcium Hydroxide based\" intracanal medicament Second group: will receive \"Bio-Ceramic Based\" intracanal medicament\n\nPostoperative pain will be assessed using:\n\n* visual analog scale (VAS), A scale from (0 to 10) where \"0\" means no pain and \"10\" means a severe pain that has never faced before.\n* Patients will be contacted by phone at 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.\n\nFlare-up is assessed:\n\n\\- by asking the patient to notify the investigator if any sudden severe pain or swelling takes place.",[56,57,58,59],"Postoperative Pain","Flare Up, Symptom","Flare up","Diabete Type 2",[61,62,63,64,65,66],"postoperative pain","flare up","diabetes type II","Intra-Canal medication","bioceramic","calcium hydroxide","NOT_YET_RECRUITING","2025-07-16",{"date":70,"type":71},"2025-07-20","ACTUAL",{"date":73,"type":50},"2025-09-01",{"date":75,"type":50},"2026-09",{"name":5,"class":6}]