[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594349":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":49,"centralContacts":57,"locations":63,"responsibleParty":81,"collaborators":84,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":36,"eligibilityCriteria":93,"healthyVolunteers":89,"sex":94,"minAge":95,"maxAge":36,"enrollmentInfo":96,"targetDuration":36,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":107,"overallStatus":65,"whyStopped":36,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"University of Siena","OTHER",[8,15,21,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Comparator: AH Plus + Continuous Wave Condensation","ACTIVE_COMPARATOR","Root canal obturation using AH Plus (Dentsply Sirona, Charlotte, NC, USA) and the continuous wave technique with thermoplasticized gutta-percha",[13,14],"Procedure: AH Plus (Dentsply Sirona, Charlotte, NC, USA)","Procedure: Continuous Wave Condensation",{"label":16,"type":17,"description":18,"interventionNames":19},"Active Comparator: AH Plus + Single Cone","EXPERIMENTAL","Root canal obturation using AH Plus and the single cone technique with cold gutta-percha.",[13,20],"Procedure: Single Cone Technique",{"label":22,"type":17,"description":23,"interventionNames":24},"NeoSealer Flo + Continuous Wave","Root canal obturation using NeoSealer Flo (Avalon Biomed, Houston, TX, USA) and the continuous wave technique.",[25,14],"Procedure: NeoSealer Flo",{"label":27,"type":17,"description":28,"interventionNames":29},"NeoSealer Flo + Single Cone","Root canal obturation using NeoSealer Flo and the single cone technique.",[25,20],[31,37,41,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"PROCEDURE","AH Plus (Dentsply Sirona, Charlotte, NC, USA)","Root canal obturation using AH Plus (Dentsply Sirona, Charlotte, NC, USA), a resin-based sealer with low solubility and shrinkage. Used in combination with gutta-percha for root canal filling",[9,16],null,{"type":32,"name":38,"description":39,"armGroupLabels":40,"otherNames":36},"NeoSealer Flo","Root canal obturation using NeoSealer Flo (Avalon Biomed, Houston, TX, USA), a premixed bioceramic sealer based on calcium silicate. Used in combination with gutta-percha to enhance apical healing and biocompatibility.",[22,27],{"type":32,"name":42,"description":43,"armGroupLabels":44,"otherNames":36},"Continuous Wave Condensation","A warm vertical compaction technique using heat-softened gutta-percha to obturate the canal in three dimensions. Considered the gold standard for achieving dense and homogenous root canal fillings.",[9,22],{"type":32,"name":46,"description":47,"armGroupLabels":48,"otherNames":36},"Single Cone Technique","A cold hydraulic condensation technique using a single gutta-percha cone matched to the last rotary file, combined with a high-flow sealer. Designed for simplified obturation with minimal operator variability",[16,27],[50,54],{"name":51,"affiliation":52,"role":53},"José Aranguren, MsC","Universidad Rey Juan Carlos , Madrid, Spain 28922","STUDY_DIRECTOR",{"name":55,"affiliation":5,"role":56},"Simone Grandini, PhD","PRINCIPAL_INVESTIGATOR",[58],{"name":59,"role":60,"phone":61,"phoneExt":36,"email":62},"Giulia Malvicini, DDS","CONTACT","Italia: +39 3487200168","giulia.malvicini@student.unisi.it",[64],{"facility":52,"status":65,"city":66,"state":36,"zip":67,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"RECRUITING","Madrid","28922","Spain","ES",{"type":71,"coordinates":72},"Point",[73,74],-3.70256,40.4165,{"lat":74,"lon":73},[77],{"name":78,"role":60,"phone":79,"phoneExt":36,"email":80},"Jose Aranguren, MsC","Spain: +34 617352993","josearanguren@hotmail.com",{"type":56,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Simone Grandini","Prof",[85],{"name":86,"class":6},"Universidad Rey Juan Carlos","100594349","postoperative-pain-evaluation-after-obturation-with-different-sealers-100594349",false,"NCT07018284","Postoperative Pain Evaluation After Obturation With Different Sealers","Assessment of Postoperative Pain Incidence in Teeth Affected by Pulpitis, Necrosis, or Previously Treated, Following Obturation With Bioceramic or Resin-based Sealers","Inclusion Criteria:\n\nPatients aged 18 years and older. Teeth with a diagnosis of pulpal necrosis or irreversible pulpitis. Informed consent provided for data usage.\n\nExclusion Criteria:\n\n* Patients with systemic conditions that may impair healing (e.g., uncontrolled diabetes, immunosuppression).\n* Asymptomatic presentation\n* Teeth with root fractures, resorption, or open apices.\n* Incomplete clinical or radiographic records.\n* Cases with poor-quality radiographs or lack of standardization for evaluation","ALL","18 Years",{"count":97,"type":98},270,"ESTIMATED","INTERVENTIONAL",[101],"NA","This study aims to evaluate the incidence and intensity of postoperative pain in patients undergoing root canal treatment on teeth diagnosed with pulpitis, pulp necrosis, or with previous endodontic treatment. Teeth will be obturated using either bioceramic or resin-based sealers. The primary objective is to determine whether the type of sealer significantly influences the level of postoperative pain as reported by patients. Pain intensity will be assessed using the Visual Analogue Scale (VAS) at three time points: immediately after treatment, 24 hours, and 72 hours postoperatively. The findings are expected to provide clinical insight into which obturation material may be more effective in minimizing postoperative discomfort.",[104,105,106],"Periapical Periodontitis","Pulpitis","Necorsis",[108,109,110],"Bioceramic sealers","Resin-based sealers","Endodontics","2025-06-04",{"date":113,"type":114},"2025-06-12","ACTUAL",{"date":116,"type":114},"2025-06-01",{"date":118,"type":98},"2026-01-30",{"name":5,"class":6},1]