[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565339":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":189,"collaborators":193,"id":213,"slug":214,"hasResults":215,"nctId":216,"briefTitle":217,"officialTitle":218,"acronym":219,"eligibilityCriteria":220,"healthyVolunteers":215,"sex":221,"minAge":222,"maxAge":223,"enrollmentInfo":224,"targetDuration":25,"studyType":227,"phases":228,"briefSummary":230,"conditions":231,"keywords":233,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":235,"lastUpdatePostDateStruct":236,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":243,"locationsCount":244},{"fullName":5,"class":6},"Amsterdam UMC, location VUmc","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention (MegaPower training)","EXPERIMENTAL","MegaPower training is a twelve-week long functional power training program in which children will perform functional power training three times a week together with a personal trainer. During the intervention, training volume will be influenced by training weight, velocity of movement, and amount of repetitions. The training program has the following characteristics:\n\n1. (Weighted) functional exercises like walking, running, and walking stairs.\n2. High velocity movements.\n3. Progressive overload.\n\nPrior to and during the training, a physiotherapist makes a personalized participation plan for the child. This plan is used to tackle participation barriers related to their goal (not directly related to mobility; e.g. beliefs or behaviours) encountered by the child (e.g. involving parents, a sports consultant, a psychologist).\n\nBoth at twelve and twenty-four weeks during the follow-up, parent and child will visit again to measure whether the effects on participation are long-lasting.",[13],"Other: MegaPower training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control (Usual Care)","ACTIVE_COMPARATOR","The control group will receive their usual care for twelve weeks (non-intervention group). This usual care consists of physiotherapy appointments, for example.",[19],"Other: Usual Care",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"MegaPower training","See arm\u002Fgroup descriptions",[9],null,{"type":6,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"Usual Care",[15],[30],{"name":31,"affiliation":32,"role":33},"Annemieke I. Buizer, prof. dr.","Amsterdam UMC","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Rijk Dersjant, drs.","CONTACT","+31 20 4440761","r.dersjant@amsterdamumc.nl",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Marjolein M. Van der Krogt, dr.","+31 20 4440789","m.vanderkrogt@amsterdamumc.nl",[45,63,77,91,107,121,134,145,161,178],{"facility":46,"status":47,"city":48,"state":49,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Treant Zorggroep","RECRUITING","Emmen","Drenthe","Netherlands","NL",{"type":53,"coordinates":54},"Point",[55,56],6.90694,52.77917,{"lat":56,"lon":55},[59],{"name":60,"role":37,"phone":61,"phoneExt":25,"email":62},"Marije Koning","+31 88 129 29 29","m.a.koning@treant.nl",{"facility":64,"status":47,"city":65,"state":66,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Merem","Almere Stad","Flevoland",{"type":53,"coordinates":68},[69,70],5.21413,52.37025,{"lat":70,"lon":69},[73,76],{"name":74,"role":37,"phone":25,"phoneExt":25,"email":75},"Elise Hooft, drs.","ehooft@merem.nl",{"name":74,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":78,"status":47,"city":79,"state":80,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Adelante zorggroep","Valkenburg","Limburg",{"type":53,"coordinates":82},[83,84],5.83205,50.86523,{"lat":84,"lon":83},[87,90],{"name":88,"role":37,"phone":25,"phoneExt":25,"email":89},"Eugene A. Rameckers, dr.","eaa.rameckers@hetnet.nl",{"name":88,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":92,"status":93,"city":94,"state":95,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Revant","NOT_YET_RECRUITING","Breda","North Brabant",{"type":53,"coordinates":97},[98,99],4.77596,51.58656,{"lat":99,"lon":98},[102,106],{"name":103,"role":37,"phone":104,"phoneExt":25,"email":105},"Jens van Helleman","+31 88 735 8000","j.vanhelleman@revant.nl",{"name":103,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":108,"status":47,"city":109,"state":110,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"Reade","Amsterdam","North Holland",{"type":53,"coordinates":112},[113,114],4.88969,52.37403,{"lat":114,"lon":113},[117,120],{"name":118,"role":37,"phone":25,"phoneExt":25,"email":119},"Liesbeth F. Van Vulpen, dr.","l.v.vulpen@reade.nl",{"name":118,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":122,"status":47,"city":123,"state":110,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":124,"geoPoint":128,"contacts":129},"Heliomare","Heemskerk",{"type":53,"coordinates":125},[126,127],4.67165,52.51108,{"lat":127,"lon":126},[130,133],{"name":131,"role":37,"phone":25,"phoneExt":25,"email":132},"Jette E. Van Egmond, drs.","je.van.egmond@heliomare.nl",{"name":131,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":64,"status":47,"city":135,"state":110,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Hilversum",{"type":53,"coordinates":137},[138,139],5.17639,52.22333,{"lat":139,"lon":138},[142,143],{"name":74,"role":37,"phone":25,"phoneExt":25,"email":75},{"name":144,"role":33,"phone":25,"phoneExt":25,"email":25},"Jeffrey van Limpt",{"facility":146,"status":47,"city":147,"state":148,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":149,"geoPoint":153,"contacts":154},"Roessingh","Enschede","Overijssel",{"type":53,"coordinates":150},[151,152],6.89583,52.21833,{"lat":152,"lon":151},[155,159],{"name":156,"role":37,"phone":157,"phoneExt":25,"email":158},"Marc Nederhand, dr.","+31 53 487 5875","m.nederhand@rrd.nl",{"name":160,"role":33,"phone":25,"phoneExt":25,"email":25},"Jolienke Colenbrander",{"facility":162,"status":47,"city":163,"state":164,"zip":165,"country":50,"countryCode":51,"cosmosGeoPoint":166,"geoPoint":170,"contacts":171},"Revalidatie Friesland","Beetsterzwaag","Provincie Friesland","9244CL",{"type":53,"coordinates":167},[168,169],6.07711,53.05914,{"lat":169,"lon":168},[172,176],{"name":173,"role":37,"phone":174,"phoneExt":25,"email":175},"Heleen Reinders-Messelink, dr.","+31 88 5801580","h.reinders-messelink@revalidatie-friesland.nl",{"name":177,"role":33,"phone":25,"phoneExt":25,"email":25},"Fokke Fennema",{"facility":92,"status":93,"city":179,"state":180,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":181,"geoPoint":185,"contacts":186},"Goes","Zeeland",{"type":53,"coordinates":182},[183,184],3.88889,51.50417,{"lat":184,"lon":183},[187,188],{"name":103,"role":37,"phone":104,"phoneExt":25,"email":105},{"name":103,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":33,"investigatorFullName":190,"investigatorTitle":191,"investigatorAffiliation":192,"oldNameTitle":25,"oldOrganization":25},"Rijk Dersjant","Coordinating investigator","VU University of Amsterdam",[194,196,199,201,203,205,206,207,208,209,210,211],{"name":195,"class":6},"Netherlands Brain Foundation",{"name":197,"class":198},"Koninklijk Nederlands Genootschap voor Fysiotherapie","UNKNOWN",{"name":200,"class":198},"De Phelps Stichting voor Spastici",{"name":202,"class":6},"Reade Rheumatology Research Institute",{"name":204,"class":6},"Adelante, Centre of Expertise in Rehabilitation and Audiology",{"name":122,"class":198},{"name":64,"class":198},{"name":92,"class":198},{"name":162,"class":198},{"name":146,"class":198},{"name":46,"class":198},{"name":212,"class":198},"Johanna Kinderfonds","100565339","power2walk-the-impact-of-functional-power-training-on-participation-and-activity-in-children-with-cerebral-palsy-100565339",false,"NCT06640894","Power2Walk: The Impact of Functional Power Training on Participation and Activity in Children With Cerebral Palsy.","Power2Walk: The Impact of Functional Power Training on Participation and Activity in Children With Cerebral Palsy - A Randomized Controlled Trial","Power2Walk","Inclusion Criteria:\n\n* Children with cerebral palsy or a related non-progressive disorder between the ages of 4 to 12.\n* Gross Motor Function Classification System (GMFCS) level I - III.\n* Parents and\u002For children have a treatment question related to participation of the child.\n\nExclusion Criteria:\n\n* Participants that suffer from a progressive neurological disorder.\n* Treatment with botulinum toxin and\u002For serial casting in lower extremities planned during the study period.\n* Treatment with botulinum toxin in the twelve weeks prior to participation in the study.\n* Treatment with serial casting in the three weeks prior to participation in the study.\n* Children that underwent a selective dorsal rhizotomy twelve months prior to participation in the study.\n* Children that underwent orthopedic surgery on their lower extremities in the 12 months before participation in the study.\n* Children that have received MegaPower training in the last 4 months before participation in the study.\n* Children for whom walking is not their preferred method of locomotion (yet).","ALL","4 Years","12 Years",{"count":225,"type":226},66,"ESTIMATED","INTERVENTIONAL",[229],"NA","Rationale: Children with cerebral palsy (CP) experience limitations in walking ability due to functional motor impairments caused by neurodevelopmental damage during fetal or early child development. Due to these motor impairments, children with CP struggle to keep up with typically developing peers when participating in physical and\u002For social activities. Consequently, the development of these children may be hampered. Recently, functional power training (FPT) emerged as a potentially successful supplementary treatment method to improve participation in children with CP. It is understood that FPT is more effective than progressive resistance training in improving walking ability and endurance, and thereby better supports participation in ambulatory children with CP. Nevertheless, high-level scientific evidence underpinning the efficacy of FPT on these parameters in ambulant children with CP is still lacking. The investigators hypothesize that FPT effectively helps accomplish patient-tailored participation and activity goals in ambulant children with CP.\n\nObjective: This study aims to investigate whether twelve weeks of FPT (MegaPower training) effectively accomplish patient-tailored participation and activity goals in ambulant children with CP, when compared to their usual care. Additionally, the goal is to investigate i) whether MegaPower training improves walking ability, aerobic endurance, and anaerobic capacity; ii) what factors best identify which ambulant children with CP benefit most from twelve weeks of MegaPower training; iii) to what extend the MegaPower training was implemented as intended in the participating study centers?, and iv) whether the effects of the MegaPower training are maintained after 12 and 24 weeks of follow-up.\n\nStudy design: A single-blind randomized controlled parallel trial with a 24 week follow-up. During the follow-up, the control group will also receive MegaPower training.\n\nStudy population: Ambulant children with cerebral palsy or a related non-progressive disorder between the ages of 4 - 12.\n\nIntervention: One group will receive twelve weeks of FPT (MegaPower training), whilst the other group will receive twelve weeks of usual care (control group).\n\nMain study parameters\u002Fendpoints: Accomplishment of patient-tailored participation and activity goals, measured through Goal Attainment Scaling.",[232],"Cerebral Palsy, Spastic",[234],"Cerebral palsy","2025-12-19",{"date":237,"type":238},"2025-12-29","ACTUAL",{"date":240,"type":238},"2024-07-19",{"date":242,"type":226},"2027-08-31",{"name":5,"class":6},10]