[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524078":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":38,"responsibleParty":52,"collaborators":55,"id":121,"slug":122,"hasResults":123,"nctId":124,"briefTitle":125,"officialTitle":125,"acronym":126,"eligibilityCriteria":127,"healthyVolunteers":123,"sex":128,"minAge":129,"maxAge":130,"enrollmentInfo":131,"targetDuration":134,"studyType":135,"phases":10,"briefSummary":136,"conditions":137,"keywords":140,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":155},{"fullName":5,"class":6},"Seoul National University Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Hybrid strategy",null,"The patient undergoes percutaneous coronary intervention with drug-coated balloons and drug-eluting stents or drug-coated balloons only in the coronary artery lesion.",[13,14],"Device: drug-coated balloon","Device: drug-eluting stent",{"label":16,"type":10,"description":17,"interventionNames":18},"DES only","The patient undergoes percutaneous coronary intervention with drug-eluting stents only in the coronary artery lesion.",[14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"DEVICE","drug-coated balloon","For the procedure, the drug-coated balloon (Agent®, Boston Scientific, USA) that can be used for both de-novo coronary lesions and in-stent restenosis lesions is used.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"drug-eluting stent","When using drug-eluting stents, the latest 2nd generation drug-eluting stent (Synergy®, Boston Scientific, USA) should be used in accordance with the latest guidelines.",[16,9],[30],{"name":31,"affiliation":32,"role":33},"Bon-Kwon Koo, MD, PhD","+82-2-2072-2062","STUDY_CHAIR",[35],{"name":31,"role":36,"phone":32,"phoneExt":10,"email":37},"CONTACT","bkkoo@snu.ac.kr",[39],{"facility":40,"status":41,"city":42,"state":10,"zip":10,"country":43,"countryCode":10,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Bon-Kwon Koo","RECRUITING","Seoul","South Korea",{"type":45,"coordinates":46},"Point",[47,48],126.9784,37.566,{"lat":48,"lon":47},[51],{"name":31,"role":36,"phone":32,"phoneExt":10,"email":37},{"type":53,"investigatorFullName":40,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Professor",[56,57,59,61,63,65,67,69,71,73,75,77,79,81,83,85,87,89,91,93,95,97,99,101,103,105,107,109,111,113,115,117,119],{"name":5,"class":6},{"name":58,"class":6},"St Vincent's Hospital",{"name":60,"class":6},"Uijeongbu St. Mary Hospital",{"name":62,"class":6},"Gachon University Gil Medical Center",{"name":64,"class":6},"Gangnam Severance Hospital",{"name":66,"class":6},"Kyunghee University Medical Center",{"name":68,"class":6},"Keimyung University Dongsan Medical Center",{"name":70,"class":6},"Inje University Ilsan Paik Hospital",{"name":72,"class":6},"Daegu Catholic University Medical Center",{"name":74,"class":6},"Sejong General Hospital",{"name":76,"class":6},"Seoul National University Bundang Hospital",{"name":78,"class":6},"Soonchunhyang University Hospital",{"name":80,"class":6},"Yeungnam University Hospital",{"name":82,"class":6},"Wonju Severance Christian Hospital",{"name":84,"class":6},"Ulsan University Hospital",{"name":86,"class":6},"Ewha Womans University Mokdong Hospital",{"name":88,"class":6},"Inje University",{"name":90,"class":6},"Chonnam National University Hospital",{"name":92,"class":6},"Chung-Ang University Gwangmyeong Hospital",{"name":94,"class":6},"Chung-Ang University Hosptial, Chung-Ang University College of Medicine",{"name":96,"class":6},"Ulsan Medical Center",{"name":98,"class":6},"Hanyang University Seoul Hospital",{"name":100,"class":6},"Jeju National University Hospital",{"name":102,"class":6},"KangWon National University Hospital",{"name":104,"class":6},"Uijeongbu Eulji University Hospital",{"name":106,"class":6},"Seoul St. Mary's Hospital",{"name":108,"class":6},"Gyeongsang National University Hospital",{"name":110,"class":6},"Severance Hospital",{"name":112,"class":6},"Chosun University Hospital",{"name":114,"class":6},"Kyungpook National University Hospital",{"name":116,"class":6},"Korea University Anam Hospital",{"name":118,"class":6},"Kyung Hee University Hospital at Gangdong",{"name":120,"class":6},"Ajou University School of Medicine","100524078","practice-change-with-drug-coated-balloon-in-patients-with-multivessel-coronary-artery-disease-100524078",false,"NCT06104033","Practice Change With Drug-coated Balloon in Patients With multiVessel Coronary Artery Disease","DCB-MVD","Inclusion Criteria:\n\n1. Age 19 or older\n2. Multivessel coronary artery disease patients requiring coronary intervention\n\n   * Stenosis of 2 or more major coronary arteries or major coronary artery branches (Vessel size ≥2.5mm) with diameter stenosis ≥50% or fractional flow reserve ≤0.80 requiring repeat revascularization\n   * Having stenotic lesions requiring revascularization with a vessel size of 2.5mm to 3.0mm\n3. Capable of understanding the risks and benefits of participating in the study and providing informed consent\n\nExclusion Criteria:\n\n1. Incapable of voluntarily providing informed consent\n2. Allergy or contraindication to aspirin, P2Y12 inhibitors, or components of drug-eluting stents\n3. Cardiogenic shock or cardiac arrest patients\n4. Patients with severe left ventricular systolic dysfunction (ejection fraction \\\u003C30%)\n5. Patients for whom coronary artery bypass surgery is prioritized over coronary artery intervention\n6. Patients with severe valvular heart disease requiring open heart surgery\n7. Pregnant or lactating women","ALL","19 Years","100 Years",{"count":132,"type":133},500,"ESTIMATED","1 Year","OBSERVATIONAL","This study is a prospective, multicenter, open-label, observational study to investigate the impact of using drug-coated balloons (DCBs) in the treatment of coronary artery lesions in patients with multivessel coronary artery disease (MVD), as opposed to the default strategy of using only drug-eluting stents (DES). The investigators aim to assess changes in clinical practice towards a hybrid treatment strategy (DES and DCB) and its effects on clinical outcomes.",[138,139],"Coronary Artery Disease","Multi Vessel Coronary Artery Disease",[141,142,143,144,145],"Coronary artery disease","Multivessel coronary artery disease","Percutaneous coronary intervention","Drug-coated balloon","Drug-eluting stent","2023-10-23",{"date":148,"type":149},"2023-10-27","ACTUAL",{"date":151,"type":149},"2023-09-18",{"date":153,"type":133},"2026-10-31",{"name":40,"class":6},1]