[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491656":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":41,"locations":46,"responsibleParty":62,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":10,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":10,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":85,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University Magna Graecia","OTHER",[8,14,18,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Oxygen Therapy (SOT)",null,"Patients receiving low oxygen flow administration through nasal prongs, oxygen mask with or without reservoir, and Venturi mask.",[13],"Diagnostic Test: Bronchoscopy",{"label":15,"type":10,"description":16,"interventionNames":17},"High Flow oxygen through Nasal Cannula (HFNC)","Administration of high flows (up to 60 L\u002Fmin) of air\u002Foxygen admixtures, heated (at temperatures ranging from 31 to 37°C) and fully humidified (up to 44 mg H2O\u002FL), providing an inspired oxygen fraction ranging from 21 to 100%",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Continuous Positive Airway Pressure (CPAP)","application of positive end-expiratory pressure (PEEP) throughout the whole respiratory cycle by means of interfaces such as mask or helmet",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Non-Invasive Ventilation (NIV)","application of a PEEP by means of a mask or helmet, with an inspiratory pressure support triggered by the patient and delivered by a ventilator and through interfaces such as mask or helmet",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Invasive Mechanical Ventilation (iMV)","application of a ventilatory assistance in controlled or partial assisted modalities through an endotracheal or tracheostomy tube",[13],[31],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"DIAGNOSTIC_TEST","Bronchoscopy","Patients will undergo to the bronchial endoscopy procedure required for their clinical condition: toilet bronchoscopy (for secretions, blood, mucus plugs removal), broncho-aspirate (BAS), bronchoalveolar lavage (BAL), brushing for cytology, biopsy, endobronchial ultrasound (EBUS).",[19,15,27,23,9],[37],{"name":38,"affiliation":39,"role":40},"Federico Longhini, MD","Magna Graecia University","PRINCIPAL_INVESTIGATOR",[42],{"name":38,"role":43,"phone":44,"phoneExt":10,"email":45},"CONTACT","+393475395967","longhini.federico@gmail.com",[47],{"facility":48,"status":49,"city":50,"state":10,"zip":10,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"AOU Mater Domini","RECRUITING","Catanzaro","Italy","IT",{"type":54,"coordinates":55},"Point",[56,57],16.60086,38.88247,{"lat":57,"lon":56},[60],{"name":38,"role":43,"phone":61,"phoneExt":10,"email":45},"+3934753959697",{"type":40,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Federico Longhini","Director of the Intensive Care and Anesthesia Department","100491656","practice-of-oxygenation-and-respiratory-support-during-fiberoptic-bronchoscopy-100491656",false,"NCT05681962","Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy","Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy: the Oxy-FOB STUDY","Inclusion Criteria:\n\n* Need for any procedure with flexible FOB\n* Either outpatients in dedicated ambulatories, and admitted to any hospital ward or Intensive Care Unit (ICU)\n\nExclusion Criteria:\n\n* None","ALL","18 Years",{"count":75,"type":76},10000,"ESTIMATED","OBSERVATIONAL","The current practice of oxygenation and\u002For ventilation supports in patients undergoing Fiberoptic Bronchoscopy is very heterogeneous among studies published in the literature; in addition, clear outcomes advantages of one strategy over another currently lack.\n\nThe goal of this observational study is to describe the current practice of oxygenation and\u002For ventilation supports in patients undergoing Fiberoptic Bronchoscopy (FOB), stratified by baseline respiratory condition, co-morbidities, type of procedure and hospital settings.\n\nInvestigators will enroll all adult patients undergoing any fiberoptic bronchoscopy in any clinical settings (from outpatients to critically ill patients). No specific exclusion criteria are indicated for enrollment in this study.\n\nInvestigators will record the following data:\n\n* Patient's baseline data.\n* Type of FOB procedure: toilet bronchoscopy (for secretions, blood, mucus plugs removal), broncho-aspirate (BAS), bronchoalveolar lavage (BAL), brushing for cytology, biopsy, endobronchial ultrasound (EBUS). The type and size of bronchoscope (with or without an internal\u002Fexternal camera) and the time of the procedure will be also recorded.\n* Type of supportive strategy: no support, Standard Oxygen Therapy, High Flow Nasal Cannula, Continuous Positive Airway Pressure and or non invasive ventilation trough mask or helmet, invasive mechanical ventilation.\n* Sedation\n* Intra-procedural vital parameters\n* Occurrence of adverse events: desaturation (i.e. SpO2\\\u003C 90% for at least 10 seconds), severe desaturation (i.e. SpO2\\\u003C 80%), need for procedure interruption, hypotensive (systolic blood pressure \\\u003C90 mmHg) or hypertensive (systolic blood pressure \\>140 mmHg) events, new onset of cardiac arrhythmias (specify the rhythm) or myocardial ischemia or electrocardiographic ST-alterations, neurological events (i.e. severe sensorium depression, psychomotor agitation).\n* Post-procedural vital parameters (15 minutes after the procedure).\n* Clinical outcomes: need for support escalation, need for admission to ward (for outpatient) or ICU (for outpatients and ward-admitted patient).",[80,81,82,83,84],"Acute Respiratory Failure","Pneumonia","Lung Cancer","Fibrosis Lung","Interstitial Lung Disease",[33],"2024-12-24",{"date":88,"type":89},"2024-12-30","ACTUAL",{"date":91,"type":89},"2023-02-15",{"date":93,"type":76},"2026-01-31",{"name":5,"class":6},1]