[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609100":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":40,"locations":50,"responsibleParty":72,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":19,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":109,"overallStatus":53,"whyStopped":19,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Aristotle University Of Thessaloniki","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Prehabilitation group","EXPERIMENTAL","This group undergo a structured preoperative self-guided exercise protocol (consisting of mild physical activity with a defined exercise program, respiratory exercise, muscle strengthening), immunonutrition (Ocoxin©) and usual clinical practice (stopping alcohol, regulating anemia and glucose levels). During the period of hospitalatization adhere to the 21-point ERAS protocol .",[13,14],"Dietary Supplement: Ocoxin","Procedure: Structured self-guided exercise",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group","NO_INTERVENTION","This group follow the usual clinical practice (stopping alcohol, regulating anemia and glucose levels). During the period of hospitalatization adhere to the 21-point ERAS protocol .",null,[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":19},"DIETARY_SUPPLEMENT","Ocoxin","Food Supplement based on Amino Acids, Plants, Vitamins and Minerals. Composition: Maltodextrin, L-Arginine, L-Cysteine, Microcrystalline cellulose, Talcum, Vitamin C (L-ascorbic acid), Zinc sulfate, Green Tea Extract (Camellia sinensis (L.) Kuntze), Manganese sulphate, Extracto de Canela (Cinnamomum verum J. Presl.), Vitamin B6 (pyridoxine hydrochloride).\n\nOcoxin utilizes Catalysis' Molecular Activation Technology (MAT) to enhance the biological activity of its natural antioxidant ingredients, such as green tea polyphenols (EGCG), to increase their antitumoral and immunomodulatory effects. This patented technology is applied to boost the efficacy of compounds within Ocoxin, such as EGCG, enabling them to exert more potent effects on cancer cells by inducing apoptosis, inhibiting tumor growth and metastasis, and supporting the body's immune response.",[9],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":19},"PROCEDURE","Structured self-guided exercise","The patient exercises in a structured manner with the help of a relevant interactive form\u002Fguide and simple aids (e.g. chair, step, water bottle, broomstick) by performing six categories of exercises: 1. Breathing exercises, 2. Pelvic floor exercises-pelvic mobility, 3. Upper trunk exercises, 4. Lower trunk exercises, 5. Aerobic exercises, 6. Stretching exercises, at a predetermined pace (number of repetitions) of each exercise and a limit of not exceeding the value 5-6 on the ten-point modified Borg fatigue scale. The intern records her activity on a form-\"exercise log\". The recommendation is the maximum implementation of the exercise program but in any case not less than 3 times a week.",[9],[32,36],{"name":33,"affiliation":34,"role":35},"Dimitrios C. Tsolakidis, MD, PhD","Professor of Obstetrics - Gynaecology, Aristotel University of Thessaloniki","STUDY_CHAIR",{"name":37,"affiliation":38,"role":39},"Panagiotis M. Tzitzis, MD, MSc","PhD (c) 1st Department of Obstetrics - Gynaecology Aristotel University of Thessaloniki","PRINCIPAL_INVESTIGATOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":19,"email":45},"Dimitrios Tsolakidis C. MD, PhD, Professor OB&GYN","CONTACT","+30 2313 32 3380","dtgyn@auth.gr",{"name":47,"role":43,"phone":48,"phoneExt":19,"email":49},"Panagiotis Tzitzis M. MD, MSc","+30 6946621179","ptzitzis@gmail.com",[51],{"facility":52,"status":53,"city":54,"state":19,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"General Hospital of Papageorgiou","RECRUITING","Thessaloniki","56429","Greece","GR",{"type":59,"coordinates":60},"Point",[61,62],22.93493,40.64072,{"lat":62,"lon":61},[65,67,68,71],{"name":37,"role":43,"phone":66,"phoneExt":19,"email":49},"+0306946621179",{"name":33,"role":39,"phone":19,"phoneExt":19,"email":19},{"name":69,"role":70,"phone":19,"phoneExt":19,"email":19},"Eleni Timotheadou, MD, PhD","SUB_INVESTIGATOR",{"name":37,"role":70,"phone":19,"phoneExt":19,"email":19},{"type":39,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Panagiotis Tzitzis","MD,MSc",[76],{"name":77,"class":78},"Catalysis SL","INDUSTRY","100609100","pre-habilitation-within-eras-protocol-for-gynecologic-oncology-surgery-the-preeras-study-100609100",false,"NCT07210164","Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study","Prehabilitation With Exercise and Immunonutrition (Ocoxin®) in the Perioperative Management of Gynecologic Malignancies Under ERAS Protocol.","Pre_ERAS","Inclusion Criteria:\n\n* Type of gynecological malignancy: endometrial cancer, ovarian cancer, cervical cancer, treated with laparotomy after the decision of the gynecological-oncology unit (positive opinion of the Multidisciplinary Tumor Board - MDT)\n* Patient age: 18 to 85 years\n* General condition of the patient: ASA score I-III\n* Consent to implement the accelerated recovery protocol - Enhanced recovery after surgery (ERAS)\n* Sufficient understanding of the Greek language\n* Provision of signed, after thorough information, consent to participate in the study\n\nExclusion Criteria:\n\n* Women with performance status: ECOG \\>2 and ASA score \\>III\n* Women who have not been informed and have given written consent","FEMALE","18 Years","85 Years",{"count":91,"type":92},100,"ESTIMATED","INTERVENTIONAL",[95],"NA","ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a quicker recovery. In gynecologic cancer surgeries, ERAS has been shown to help patients do better, have fewer problems, and leave the hospital sooner.\n\nA prehabilitation program, in combination with ERAS protocols, aims to optimize patients' physical and psychological condition prior to surgery for gynecological cancers. Interventions may include tailored exercise, nutritional support, respiratory training, and psychological preparation. By enhancing baseline fitness and resilience, prehabilitation improves the body's ability to tolerate surgical stress, reduces complications, and facilitates a faster, smoother recovery within the ERAS framework.",[98,99,100,101,102,103,104,105,106,107,108],"ERAS","Compliance","Quality of Life (QOL)","Excercise","Immunonutrition","Post Operative Pain","Laparotomy Patients","Surgical Complication","Gynaecological Malignancies","Gynaecologic Cancer","Gynaecological Oncology",[110,98,111,102],"Prehabilitation","Gynecologic Cancers","2025-09-29",{"date":114,"type":115},"2025-10-07","ACTUAL",{"date":117,"type":92},"2025-12-01",{"date":119,"type":92},"2029-12-30",{"name":5,"class":6},1]