[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538400":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":63,"collaborators":66,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":25,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Linkoeping University","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","Pre-operative exercise therapy and education before knee replacement surgery",[13,14],"Other: Pre-operative exercise therapy and education","Other: Standardized pre-operative information session",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group","OTHER","Standard care",[14],[21,26],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Pre-operative exercise therapy and education","Pre-operative supervised exercise therapy consisting of individualized strength, mobility and balance exercises and continuous education through individual discussions of expectations of post-operative recovery, pain and swelling, course of rehabilitation, long term function and activity level etc. Twice a week, approximately one hour\u002Fsession.",[9],null,{"type":17,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standardized pre-operative information session","As part of the standard care procedure, patients in the intervention and control group will participate in a standardized pre-operative information session approximately 2 weeks before surgery. General information regarding preparations before surgery (e.g. preparing the home environment), events during the hospital stay and the rehabilitation process after discharge will be provided.",[16,9],[31],{"name":32,"affiliation":5,"role":33},"Marcus Ljung, PhD-student","STUDY_DIRECTOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+4610-1043861","marcus.ljung@regionostergotland.se",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":42},"Joanna Kvist, Professor","+46732713077","joanna.kvist@liu.se",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Linkoping University","RECRUITING","Linköping","Östergötland County","58183","Sweden","SE",{"type":53,"coordinates":54},"Point",[55,56],15.62157,58.41086,{"lat":56,"lon":55},[59,61],{"name":40,"role":36,"phone":60,"phoneExt":25,"email":42},"+46 (0) 13 284664",{"name":40,"role":62,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":62,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Joanna Kvist","Professor",[67,69],{"name":68,"class":17},"Region Östergötland",{"name":70,"class":6},"Region Jönköping County","100538400","pre-operative-exercise-therapy-and-patient-education-before-total-knee-replacement-100538400",false,"NCT06290336","Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement","Effect of Prehabilitation Before Total Knee Replacement on Post-operative Patient-reported Joint Awareness, Enablement and Knee Function","PROTEKT","Inclusion Criteria:\n\n* Waiting list for primary unilateral knee replacement surgery\n* Osteoarthritis of the knee being the primary reason for surgery\n* Reside within 60 minutes of travel to the site of the intervention\n\nExclusion Criteria:\n\n* Previous knee replacement surgery in the other knee\n* Other reason than osteoarthritis of the knee as the primary reason for surgery\n* Impaired cognitive function\n* Not being independent speaking and reading in swedish language\n* Chronic illness or disability etc hindering full participation in the intervention","ALL","40 Years","85 Years",{"count":83,"type":84},110,"ESTIMATED","INTERVENTIONAL",[87],"NA","The goal of this multi-center randomized controlled trial is to investigate the effect of pre-operative exercise therapy and education for patients awaiting knee replacement surgery on subjective knee function, patient satisfaction and enablement compared to standard care.\n\nThe main questions it aims to answer are:\n\n* Does pre-operative exercise therapy and education lead to better subjective knee function compared to standard care one year after surgery?\n* Does pre-operative exercise therapy and education lead to a higher level of patient satisfaction compared to standard care one year after surgery?\n* Does pre-operative exercise therapy and education lead to better patient enablement compared to standard care six weeks after surgery?\n* Does pre-operative exercise therapy and education lead to better objective knee function compared to standard care six weeks after surgery?\n\nParticipants will be randomized stratified by age (≤ 67 years, \\> 67 years) to either pre-operative supervised individualized exercise therapy combined with education two sessions\u002Fweek (intervention group) or to standard care (control group). The intervention will be continuously ongoing for at least eight weeks from the point of decision for surgery until as close to the surgery as possible.",[90],"Knee Osteoarthritis",[92,93,94,95,96],"Knee replacement","Exercise therapy","Education","Knee function","Satisfaction","2026-01-30",{"date":99,"type":100},"2026-02-03","ACTUAL",{"date":102,"type":100},"2024-02-26",{"date":104,"type":84},"2027-12-30",{"name":5,"class":6},1]