[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594852":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":45,"collaborators":47,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University College, London","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Patient participants for qualitative stage (stage 1)",null,"Semi-structured interviews will first be conducted among 20-30 people undergoing testing for latent tuberculosis infection, as part of routine clinical screening programmes (Stage 1).",{"label":13,"type":10,"description":14,"interventionNames":10},"Patient participants for discrete choice experiment (stage 2)","200 patients will then undertake a quantitative discrete choice experiment to evaluate preferences and trade-offs that influence acceptance of preventive TB treatment.",{"label":16,"type":10,"description":17,"interventionNames":10},"Healthcare worker participants for discrete choice experiment (stage 2)","200 healthcare workers will also undertake a quantitative discrete choice experiment to evaluate preferences and trade-offs that influence recommendation of preventive TB treatment.",[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Rishi K Gupta, PhD","CONTACT","020 3549 5979","r.gupta@ucl.ac.uk",[25],{"facility":26,"status":27,"city":28,"state":10,"zip":10,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Whittington Hospital","RECRUITING","London","United Kingdom","UK",{"type":32,"coordinates":33},"Point",[34,35],-0.12574,51.50853,{"lat":35,"lon":34},[38,42],{"name":39,"role":21,"phone":40,"phoneExt":10,"email":41},"Rubin Rose-Key","07771472837","r.rose-key@ucl.ac.uk",{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},"Mahdad Noursadeghi","PRINCIPAL_INVESTIGATOR",{"type":46,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[48],{"name":49,"class":6},"University of Aberdeen","100594852","precision-biomarker-guided-management-of-tuberculosis-contacts-a-discrete-choice-experiment-100594852",false,"NCT07024836","PRecision biomArker-Guided MAnagement of TuberculosIs Contacts: a Discrete Choice Experiment","PRAGMATIC-DCE","Inclusion Criteria:\n\n* Adults (aged ≥18 years) who have been tested for latent TB infection in routine clinical services, or are eligible for testing. Eligible people for testing include migrants from countries with high TB incidence (entered UK within 5 years), people with recent contact with a person with TB disease, and people eligible for LTBI screening prior to starting immunosuppression or through occupational health testing.\n\nExclusion Criteria:\n\n* Unable to provide informed consent.","ALL","18 Years",{"count":60,"type":61},430,"ESTIMATED","OBSERVATIONAL","This study is part of a broader programme of work to develop and pilot a randomised-controlled trial of new tests to identify people who will benefit most from preventive treatment for tuberculosis (TB). The aim of the current study is to explore factors affecting patient decisions to start preventive treatment. The specific objectives are to understand how patients make decisions about preventive treatment initiation for TB (stage 1); and to design and conduct a \"discrete choice experiment\" survey to further evaluate preferences (stage 2).",[65],"Tuberculosis (TB)",[67,68,69,70],"preference","discrete choice experiment","qualitative","latent tuberculosis infection","2025-06-09",{"date":73,"type":74},"2025-06-17","ACTUAL",{"date":76,"type":74},"2025-05-22",{"date":78,"type":61},"2026-12",{"name":5,"class":6},1]