[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589907":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":22,"locations":11,"responsibleParty":28,"collaborators":11,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":11,"eligibilityCriteria":36,"healthyVolunteers":32,"sex":37,"minAge":38,"maxAge":39,"enrollmentInfo":40,"targetDuration":11,"studyType":43,"phases":44,"briefSummary":46,"conditions":47,"keywords":49,"overallStatus":55,"whyStopped":11,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":11},{"fullName":5,"class":6},"He Eye Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Precision Lifestyle Intervention (PLI) group","EXPERIMENTAL",null,[13],"Behavioral: Precision Lifestyle Intervention (PLI) group",{"label":15,"type":16,"description":11,"interventionNames":11},"Health Education (HE) group","NO_INTERVENTION",[18],{"type":19,"name":9,"description":20,"armGroupLabels":21,"otherNames":11},"BEHAVIORAL","1. Device Application: Participants in the intervention group will wear the GX-01S continuous glucose monitoring system, with data transmitted in real-time to a secure cloud platform.\n2. Multidisciplinary Management: A specialized team (health managers, nutritionists, endocrinologists, and Counselor) will analyze glucose fluctuations, dietary patterns, sleep health, physical activity and to formulate personalized adjustment plans. Modifications may include meal timing optimization, sleep duration regulation, and exercise frequency adaptations.\n3. Telehealth Follow-up: Participants will receive structured guidance via telephone\u002Ftelemedicine consultations throughout the 28-day intervention period. Type 2 Diabetes Mellitus (T2DM) patient compliance will be systematically monitored and documented.\n4. Tailored Recommendations: Evidence-based lifestyle recommendations will be provided post-intervention, informed by quantitative biomarker data and adherence metrics collected.",[9],[23],{"name":24,"role":25,"phone":26,"phoneExt":11,"email":27},"tongtong zhang Principal Investigator","CONTACT","086-13840113609","hzhangtongtong@163.com",{"type":29,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100589907","precision-lifestyle-interventions-guided-by-continuous-glucose-monitoring-impact-on-glycemic-outcomes-in-type-2-diabetes-mellitus-100589907",false,"NCT06960512","Precision Lifestyle Interventions Guided by Continuous Glucose Monitoring: Impact on Glycemic Outcomes in Type 2 Diabetes Mellitus","The Impact of Precision Lifestyle Intervention on Blood Glucose Control in Type 2 Diabetes Mellitus","Inclusion Criteria:\n\n* Comply with the diagnostic criteria for T2DM in the 'Clinical guidelines for prevention and treatment of type 2 diabetes mellitus in the elderly in China (2020 edition)', and be diagnosed with type 2 diabetes mellitus, i.e., mainly due to insulin resistance and insufficient relative insulin secretion, and have the typical symptoms of diabetes mellitus (irritable thirst and excessive drinking, excessive urination, excessive food intake, and unexplained weight loss) plus a random glucose level ≥11.1 mmol\u002FL (200 mg\u002Fdl), or plus a fasting Blood glucose level ≥ 7.0 mmol\u002FL (126 mg\u002Fdl), or plus random blood glucose or OGTT (Oral Glucose Tolerance Test) 2-hour blood glucose level ≥ 11.1 mmol\u002FL (200 mg\u002Fdl), or plus glycated hemoglobin (HbA1c) level ≥ 6.5%;\n* Age 18～65 years old (including the threshold), gender is not limited;\n* Can skillfully operate a smartphone by themselves, or their family members can help to use the phone to give feedback on their daily life situation;\n* Willing to participate in this study with good compliance;\n* Agree to authorize He Eye Specialist Hospital to make cases of health management content.\n\nExclusion Criteria:\n\n* Pregnant women, lactating women, and women of childbearing age who do not wish to use contraception during the research period;\n* Severe skin disease, adhesive tape or adhesive allergy at the sensor placement site;\n* People with a history of specific allergies, or allergies (e.g., allergic to two or more drugs, food, or pollen);\n* Patients who meet the criteria for Grade 3 hypertension according to the ratings in the' Chinese Guidelines for the Prevention and Treatment of Hypertension (2024 Revision)', i.e., blood pressure over 180\u002F110 mmHg, or low blood pressure of 110 mmHg or more;\n* Suffering from severe cardiovascular and cerebrovascular diseases (including ST-segment elevation myocardial infarction, unstable angina up to Braunwald classification III (one or more episodes of resting angina within 48 hours), transient ischemic attack, stroke treatment accompanied by various degrees of sequelae (e.g.,hemiplegia,aphasia,impaired consciousness, epilepsy, and even dementia), coronary artery stenosis of moderate stenosis (50%) and above, hemodialysis reconstruction surgery less than 6 months, cerebral embolism and cerebral hemorrhage less than 6 months or with varying degrees of movement disorders after the treatment, cognitive disorders, speech and swallowing disorders, and other sequelae, etc.), or daily accompanied by frequent episodes of angina pectoris, chest tightness, chest pain and other symptoms;\n* Renal insufficiency up to stage III and above (blood creatinine level more than 450μmol\u002FL);\n* History of psychoSsis or psychotropic substance abuse;\n* Any condition judged by the investigator to be unsuitable for participation.","ALL","18 Years","65 Years",{"count":41,"type":42},200,"ESTIMATED","INTERVENTIONAL",[45],"NA","This study is an interventional research. Through scientific evaluation, it explores the effect of precise lifestyle intervention based on CGM data on the control of chronic type 2 diabetes mellitus. By formulating a safe and effective precise lifestyle intervention plan, lifestyle medicine is integrated into the management of chronic diseases. Through multidimensional evaluations, it is expected to improve patients' self-management ability and provide a reference for the development of chronic diabetes management.",[48],"Type 2 Diabetes Mellitus (T2DM)",[50,51,52,53,54],"lifestyle medicine","Type 2 Diabetes Mellitus","continuous glucose monitoring","HBA1c","Glycosylated hemoglobin","NOT_YET_RECRUITING","2025-05-05",{"date":58,"type":59},"2025-05-07","ACTUAL",{"date":61,"type":42},"2025-05",{"date":63,"type":42},"2026-12",{"name":5,"class":6}]