[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552325":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":22,"responsibleParty":39,"collaborators":41,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":7,"enrollmentInfo":55,"targetDuration":7,"studyType":58,"phases":7,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":24,"whyStopped":7,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Insel Gruppe AG, University Hospital Bern","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Uyen Huynh-Do, Prof. MD","University Hospital Bern (Inselspital)","PRINCIPAL_INVESTIGATOR",[14,18],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},"CONTACT","+41316323144","uyen.huynh-do@insel.ch",{"name":19,"role":15,"phone":20,"phoneExt":7,"email":21},"Stefan Rudloff, PhD","+41316329817","stefan.rudloff@unibe.ch",[23],{"facility":11,"status":24,"city":25,"state":7,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Bern","3010","Switzerland","CH",{"type":30,"coordinates":31},"Point",[32,33],7.44744,46.94809,{"lat":33,"lon":32},[36,38],{"name":10,"role":15,"phone":37,"phoneExt":7,"email":17},"+41316323141",{"name":19,"role":15,"phone":20,"phoneExt":7,"email":21},{"type":40,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[42],{"name":43,"class":44},"CSL Behring","INDUSTRY","100552325","precision-medicine-in-cardiovascular-surgery-associated-acute-kidney-injury-100552325",false,"NCT06471621","Precision Medicine in Cardiovascular Surgery Associated Acute Kidney Injury","PrEcision Medicine in the Management of Cardiovascular Surgery Associated AKI - PEAK: a Prospective Observational Cohort Study","PEAK","Inclusion Criteria:\n\n* Patients undergoing elective cardiovascular surgery, such as valvular replacement surgery, with or without combined coronary artery bypass graft (CABG), or thoracic or abdominal aortic surgery.\n* Written informed consent obtained prior to surgery.\n\nExclusion Criteria:\n\n* Patients with a kidney transplant or on renal replacement therapy\n* Severe liver failure, defined by the presence of encephalopathy, Factor V \\\u003C 50% and INR \\>1.5 on preoperative blood sample (within 4 weeks).","ALL","18 Years",{"count":56,"type":57},100,"ESTIMATED","OBSERVATIONAL","The goal of this prospective observational study is to define a risk profile for cardiovascular surgery associated acute kidney injury (AKI), using clinical patient characteristics, operation parameters as well as blood and urine laboratory values.\n\nThe main question it aims to answer is:\n\n• Does a combination of the factors mentioned above better predict patient outcome than classical factors used to date in clinical practice?\n\nParticipants of this study are adults aged 18 and above who are scheduled for elective heart or main artery surgery, and who have given written informed consent.",[61,62,63],"Acute Kidney Injury","Surgery-Complications","Frailty",[65,66,67,68,69,70,71,72,73,74],"Kidney","Renal","Cardiac","Thoracic","Abdominal","Valvular replacement","CABG","Aneurysm","cardiopulmonary bypass","Ischemia","2024-07-17",{"date":77,"type":78},"2024-07-19","ACTUAL",{"date":80,"type":78},"2024-06-16",{"date":82,"type":57},"2026-10-31",{"name":5,"class":6},1]