[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591320":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":19,"responsibleParty":64,"collaborators":10,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":10,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":22,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Douglas Mental Health University Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Early Psychosis Patients",null,"This study will participants recruited from three Early Psychosis Intervention (EPI) programs across Ontario and Quebec.\n\nThis group will consist of approximately 250 patients experiencing or having experienced psychosis, enrolled in the EPI programs.",[13],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},"Lena Palaniyappan, MD, PHD","CONTACT","5147616131","6116","lena.palaniyappan@mcgill.ca",[20,39,50],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Robarts Research Institute","RECRUITING","London","Ontario","N6A 5B7","Canada","CA",{"type":29,"coordinates":30},"Point",[31,32],-81.23304,42.98339,{"lat":32,"lon":31},[35],{"name":36,"role":15,"phone":37,"phoneExt":10,"email":38},"Michael MacKinley, PHD","519.931.5777","michael.mackinley@lhsc.on.ca",{"facility":5,"status":22,"city":40,"state":41,"zip":42,"country":26,"countryCode":27,"cosmosGeoPoint":43,"geoPoint":47,"contacts":48},"Montreal","Quebec","H4H 1A8",{"type":29,"coordinates":44},[45,46],-73.58781,45.50884,{"lat":46,"lon":45},[49],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},{"facility":51,"status":22,"city":52,"state":41,"zip":53,"country":26,"countryCode":27,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Vitam","Québec","G1J 2G1",{"type":29,"coordinates":55},[56,57],-71.21454,46.81228,{"lat":57,"lon":56},[60],{"name":61,"role":15,"phone":62,"phoneExt":10,"email":63},"Amélie M Achim, Phd","418 663-5741","amelie.achim@fmed.ulaval.ca",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Lena Palaniyappan","Director, Centre of Excellence in Youth Mental Health","100591320","predicting-psychotic-relapse-using-speech-based-early-detection-100591320",false,"NCT06978894","Predicting Psychotic Relapse Using Speech-Based Early Detection","MOTS+","Inclusion Criteria:\n\n* Age must be 16 years and older\n* Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions\n* Fluency in English or French\n* Must be currently receiving treatment through an EPI program\n\nExclusion Criteria:\n\n* Severe comorbid speech or language disorders (e.g., aphasia)\n* Primary diagnosis of non-psychotic disorders\n* Inability to provide consent or complete assessments","ALL","16 Years",{"count":78,"type":79},250,"ESTIMATED","OBSERVATIONAL","Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse prediction",[83],"Psychosis",[85,86,87,88,89],"psychosis","natural language processing","relapse","speech","relapse prediction","2025-05-11",{"date":92,"type":93},"2025-05-18","ACTUAL",{"date":95,"type":93},"2024-05-27",{"date":97,"type":79},"2029-07-01",{"name":5,"class":6},3]