[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552611":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":48,"centralContacts":53,"locations":58,"responsibleParty":78,"collaborators":81,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":89,"acronym":35,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":35,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":35,"overallStatus":61,"whyStopped":35,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"State University of New York at Buffalo","OTHER",[8,17,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"30\u002F30 work\u002Frest cycle first","ACTIVE_COMPARATOR","Participants will first complete the 30\u002F30 work\u002Frest cycle, and then complete the other three conditions in a randomized fashion",[13,14,15,16],"Other: 30\u002F30 work\u002Frest cycle","Other: 30\u002F20 work\u002Frest cycle","Other: 40\u002F30 work\u002Frest cycle","Other: 20\u002F12 work\u002Frest cycle",{"label":18,"type":19,"description":20,"interventionNames":21},"30\u002F20 work\u002Frest cycle first","EXPERIMENTAL","Participants will first complete the 30\u002F20 work\u002Frest cycle, and then complete the other three conditions in a randomized fashion",[13,14,15,16],{"label":23,"type":19,"description":24,"interventionNames":25},"40\u002F30 work\u002Frest cycle first","Participants will first complete the 40\u002F30 work\u002Frest cycle, and then complete the other three conditions in a randomized fashion",[13,14,15,16],{"label":27,"type":19,"description":28,"interventionNames":29},"20\u002F12 work\u002Frest cycle first","Participants will first complete the 20\u002F12 work\u002Frest cycle, and then complete the other three conditions in a randomized fashion",[13,14,15,16],[31,36,40,44],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"30\u002F30 work\u002Frest cycle","Participants will walk on a treadmill while wearing a weighted backpack to a work\u002Frest cycle of 30 minutes of work followed by 30 minutes of rest.",[27,18,9,23],null,{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"30\u002F20 work\u002Frest cycle","Participants will walk on a treadmill while wearing a weighted backpack to a work\u002Frest cycle of 30 minutes of work followed by 20 minutes of rest.",[27,18,9,23],{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"40\u002F30 work\u002Frest cycle","Participants will walk on a treadmill while wearing a weighted backpack to a work\u002Frest cycle of 40 minutes of work followed by 30 minutes of rest.",[27,18,9,23],{"type":6,"name":45,"description":46,"armGroupLabels":47,"otherNames":35},"20\u002F12 work\u002Frest cycle","Participants will walk on a treadmill while wearing a weighted backpack to a work\u002Frest cycle of 20 minutes of work followed by 12 minutes of rest.",[27,18,9,23],[49],{"name":50,"affiliation":51,"role":52},"Riana R Pryor, PhD","University at Buffalo","PRINCIPAL_INVESTIGATOR",[54],{"name":50,"role":55,"phone":56,"phoneExt":35,"email":57},"CONTACT","7168295456","rpryor@buffalo.edu",[59],{"facility":60,"status":61,"city":62,"state":63,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"Center for Research and Education in Special Environments","RECRUITING","Buffalo","New York","14214","United States","US",{"type":68,"coordinates":69},"Point",[70,71],-78.87837,42.88645,{"lat":71,"lon":70},[74],{"name":75,"role":55,"phone":76,"phoneExt":35,"email":77},"Riana R Pryor, PhD, ATC","716-829-5456","RPryor@buffalo.edu",{"type":52,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"Riana Pryor","Assistant Professor",[82],{"name":83,"class":84},"United States Department of Defense","FED","100552611","predicting-responses-to-exhausting-prolonged-and-repeated-exercise-demands-prepared-for-heat-100552611",false,"NCT06475339","Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat","Inclusion Criteria:\n\n* Healthy individuals\n* Physically active\n\nExclusion Criteria:\n\n* History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease\n* Hypertensive (systolic blood pressure \\> 139 mmHg, diastolic blood pressure \\> 89 mmHg) or tachycardic (heart rate \\> 100 bpm) during the screening visit\n* Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)\n* Tobacco or nicotine use currently or in the past six months\n* Musculoskeletal injury expected to impact exercise in the protocol\n* A positive pregnancy test at any point in the study\n* Study physician discretion based on any other medical condition or medication\n* Inability to understand or follow instructions or the protocol\n* Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.",true,"ALL","18 Years","39 Years",{"count":96,"type":97},24,"ESTIMATED","INTERVENTIONAL",[100],"NA","The overall goal of this project is to identify a work\u002Frest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.",[103,104],"Hyperthermia","Fatigue; Heat","2026-01-22",{"date":107,"type":108},"2026-01-26","ACTUAL",{"date":110,"type":108},"2024-11-01",{"date":112,"type":97},"2027-03",{"name":5,"class":6},1]