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tumor DNA",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","circulating tumor DNA","blood sample and tissue specimen for circulating tumor DNA will be done to patient with hepatocellular carcinoma",[9],[21],{"name":22,"affiliation":23,"role":24},"Mingxin Pan","Southern Medical University","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Mingxin Pan, Prof.","CONTACT","+8618928918216","pmxwxy@sohu.com",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},"Cheng Zhang","13242781120","754167410@qq.com",[36,55,70,80,90,100,110],{"facility":37,"status":38,"city":39,"state":40,"zip":10,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"The Sixth Affiliated Hospital of South China University of 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Prof.","13702835586",{"name":97,"role":24,"phone":10,"phoneExt":10,"email":10},{"facility":101,"status":38,"city":57,"state":40,"zip":10,"country":41,"countryCode":42,"cosmosGeoPoint":102,"geoPoint":104,"contacts":105},"Sun Yat-sen University Cancer Center",{"type":44,"coordinates":103},[61,62],{"lat":62,"lon":61},[106,109],{"name":107,"role":28,"phone":108,"phoneExt":10,"email":10},"Rongping Guo, Prof.","18819809988",{"name":107,"role":24,"phone":10,"phoneExt":10,"email":10},{"facility":111,"status":38,"city":112,"state":40,"zip":10,"country":41,"countryCode":42,"cosmosGeoPoint":113,"geoPoint":117,"contacts":118},"Yuebei People's Hospital","Shaoguan",{"type":44,"coordinates":114},[115,116],113.58333,24.8,{"lat":116,"lon":115},[119],{"name":120,"role":28,"phone":121,"phoneExt":10,"email":10},"Qingsong Wu, Prof.","13826368658",{"type":123,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100528153","prediction-of-hepatocellular-carcinoma-recurrence-after-curative-treatment-by-longitudinal-monitoring-mrd-based-on-ctdna-100528153",false,"NCT06157060","Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Longitudinal Monitoring MRD Based on ctDNA","Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Longitudinal Monitoring Minimal Residual Disease Based on Circulating Tumor DNA","Inclusion Criteria:\n\n1. Male or female patients aged 18-75 years;\n2. Preoperative imaging examination diagnosed hepatocellular carcinoma (BCLC) stage 0 \u002F stage A\u002Fstage B, eligible for radical surgery;\n3. ECOG physical status score is 0-1;\n4. Child-Pugh score is 5-6 points (Level A);\n5. Not received any anti-tumor therapy;\n6. Laboratory tests were at normal levels within 7 days before enrollment.\n\nExclusion Criteria:\n\n1. Patient can't provide blood samples for ctDNA testing;\n2. Patient with two or more types of tumors at the same time;\n3. Non-primary liver lesions;\n4. Pregnant or lactating women;\n5. Patient with a history of other malignant tumors within the past 5 years or at the same time, except cured skin basal cell carcinoma, cervical carcinoma in situ and thyroid papillary carcinoma;\n6. Patient with serious heart disease;\n7. Other conditions deemed unsuitable for inclusion by the researcher.","ALL","18 Years","75 Years",{"count":135,"type":136},255,"ESTIMATED","OBSERVATIONAL","This study will conduct a prospective cohort study to verify the predictive value of ctDNA-MRD longitudinal monitoring model in predicting postoperative recurrence, verify whether ctDNA-MRD longitudinal monitoring model can indicate recurrence earlier than imaging examination, and explore the feasibility of guiding adjuvant therapy after curative treatment based on this model.",[140],"Hepatocellular Carcinoma Resectable","2026-03-18",{"date":143,"type":144},"2026-03-20","ACTUAL",{"date":146,"type":144},"2023-11-20",{"date":148,"type":136},"2028-11-30",{"name":5,"class":6},7]