[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642685":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":40,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":55,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":67,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Antalya Health Sciences University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients Aged 65 Years and Older with Acute Pancreatitis",null,"This cohort will include patients aged 65 years and older diagnosed with acute pancreatitis in the emergency department. Data will be collected retrospectively from electronic medical records. No intervention will be administered. NEWS-2 and NEWS-Calcium scores will be calculated using admission data, and their predictive performance for in-hospital mortality will be compared.",[13],"Other: Retrospective Calculation of NEWS-2 Score",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Retrospective Calculation of NEWS-2 Score","he National Early Warning Score 2 (NEWS-2) will be calculated retrospectively using physiological parameters recorded at emergency department admission, including respiratory rate, oxygen saturation, systolic blood pressure, pulse rate, level of consciousness, body temperature, and supplemental oxygen use. No intervention will be administered to patients as part of this study.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"MURAT DUYAN, ASSOCIATE PROFESSOR","CONTACT","+905404120735","drmuratduyan@gmail.com",[26],{"facility":27,"status":10,"city":28,"state":29,"zip":30,"country":31,"countryCode":10,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"University of Health Sciences, Antalya Training and Research Hospital","Antalya","konyaaltı","07100","Turkey (Türkiye)",{"type":33,"coordinates":34},"Point",[35,36],30.69556,36.90812,{"lat":36,"lon":35},[39],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"type":41,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100642685","predictive-performance-of-news-2-and-news-calcium-scores-for-in-hospital-mortality-in-older-patients-with-acute-pancreatitis-100642685",false,"NCT07640971","Predictive Performance of NEWS-2 and NEWS-Calcium Scores for In-Hospital Mortality in Older Patients With Acute Pancreatitis","Comparison of the Predictive Performance of NEWS-2 and NEWS-Calcium Scores on In-Hospital Mortality in Patients Aged 65 Years and Older Diagnosed With Acute Pancreatitis in the Emergency Department.","NEWS","Inclusion Criteria:\n\n* Age 65 years or older.\n* Admission to the emergency department with a diagnosis of acute pancreatitis during the study period.\n* Diagnosis of acute pancreatitis established according to clinical presentation, serum pancreatic enzyme levels, and\u002For imaging findings.\n* Availability of admission vital parameters required to calculate the National Early Warning Score 2 (NEWS-2).\n* Availability of serum calcium measurement at emergency department admission.\n* Availability of in-hospital clinical outcome data.\n\nExclusion Criteria:\n\n* Age younger than 65 years.\n* Absence of a confirmed diagnosis of acute pancreatitis.\n* Missing data required to calculate NEWS-2 or NEWS-Calcium scores.\n* Missing serum calcium measurement at admission.\n* Incomplete medical records or unavailable in-hospital outcome data.\n* Transfer to another hospital before clinical outcome assessment.\n* Recurrent admissions during the study period; only the first eligible admission will be analyzed.","ALL","65 Years",{"count":53,"type":54},350,"ESTIMATED","1 Month","OBSERVATIONAL","Acute pancreatitis is an important gastrointestinal emergency that may lead to mortality, particularly in older patients. This retrospective, single-center observational prognostic validation study aims to compare the predictive performance of the National Early Warning Score 2 (NEWS-2) and NEWS-Calcium scores for in-hospital mortality in patients aged 65 years and older diagnosed with acute pancreatitis in the emergency department.\n\nElectronic medical records of eligible patients will be reviewed retrospectively. Demographic characteristics, vital signs, serum calcium levels, clinical outcomes, intensive care unit admission, organ failure, length of hospital stay, and in-hospital mortality will be recorded. NEWS-2 will be calculated using vital parameters at admission, while the NEWS-Calcium score will be obtained by adding a calcium-based score to NEWS-2.\n\nThe primary outcome will be in-hospital mortality. Secondary outcomes will include intensive care unit admission, severe acute pancreatitis, persistent organ failure, and length of hospital stay. The predictive performances of the scores will be compared using ROC curve analysis, AUC values, and the DeLong test. This study aims to identify the most appropriate early prognostic score for older patients with acute pancreatitis and to support clinical decision-making in emergency settings.",[59,60,61],"Acute Pancreatitis (AP)","News-2","Prediction of In-Hospital Mortality in Older Patients With Acute Pancreatitis",[63,64,65,66],"Acute Pancreatitis","In-Hospital Mortality","Older Adults","Emergency Department Risk Stratification","NOT_YET_RECRUITING","2026-06-06",{"date":70,"type":71},"2026-06-11","ACTUAL",{"date":73,"type":54},"2026-07-15",{"date":75,"type":54},"2026-10-15",{"name":5,"class":6},1]