[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626642":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":66,"collaborators":10,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":10,"enrollmentInfo":78,"targetDuration":81,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Singapore General Hospital","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients with liver cirrhosis",null,[12],"Other: Observation",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Observation","Patients with liver cirrhosis will be observed to monitor for death",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Jason Pik Eu Chang, MBBS, MRCP","CONTACT","+65 6321 4684","jason.chang@singhealth.com.sg",[25,44,56],{"facility":26,"status":27,"city":28,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Changi General Hospital","RECRUITING","Singapore","SG",{"type":31,"coordinates":32},"Point",[33,34],103.85007,1.28967,{"lat":34,"lon":33},[37,41],{"name":38,"role":21,"phone":39,"phoneExt":10,"email":40},"Rahul Kumar, MBBS, MRCP","+65 6788883","rahul.kumar@singhealth.com.sg",{"name":42,"role":43,"phone":10,"phoneExt":10,"email":10},"Rahul Kumar","PRINCIPAL_INVESTIGATOR",{"facility":45,"status":27,"city":28,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":46,"geoPoint":48,"contacts":49},"Sengkang General Hospital",{"type":31,"coordinates":47},[33,34],{"lat":34,"lon":33},[50,54],{"name":51,"role":21,"phone":52,"phoneExt":10,"email":53},"Marianne Anastasia De Roza, MBBS, MRCP","+65 6930500","marianne.anastasia.d.r@singhealth.com.sg",{"name":55,"role":43,"phone":10,"phoneExt":10,"email":10},"Marianne Anastasia De Roza",{"facility":5,"status":27,"city":28,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":57,"geoPoint":59,"contacts":60},{"type":31,"coordinates":58},[33,34],{"lat":34,"lon":33},[61,64],{"name":62,"role":21,"phone":63,"phoneExt":10,"email":23},"Jason Chang, MBBS, MRCP","+6321 4684",{"name":65,"role":43,"phone":10,"phoneExt":10,"email":10},"Chang Jason",{"type":67,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100626642","predictors-of-decompensation-acute-on-chronic-liver-failure-and-mortality-in-liver-cirrhosis-100626642",false,"NCT07438288","Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis","Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis - a Multicentre, Prospective, Observational Study From the SingHealth Chronic Liver Disease Registry (SoLiDaRity-DAM)","SoLiDaRity","Inclusion Criteria:\n\n1. Patients with clinical diagnosis of liver cirrhosis\n2. Age 18 years and above (parental consent required if below 21 years)\n3. Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* No clinical evidence of liver cirrhosis\n* Not willing to provide informed consent","ALL","18 Years",{"count":79,"type":80},2200,"ESTIMATED","10 Years","OBSERVATIONAL","The purpose of this study is to identify factors that predict the development of decompensation, acute-on-chronic liver failure (ACLF) and death in patients with liver cirrhosis. Clinical data will be retrieved from existing hospital records. This information may help doctors to identify patients with cirrhosis who are at risk of deterioration earlier (before they develop complications) and to develop effective treatment strategies to prevent or delay these complications.\n\nThis study is designed as a prospective, non-interventional, observational study. This means that if you agree to participate in the study, you will not be required to undergo any additional hospital visits, tests, procedures or interventions other than the usual standard-of-care management that your doctor will provide. If you consent to participate in this study, you will be providing the study investigators permission to review and analyse your clinical data from the hospital clinical records. Your data will be collected throughout the course of your disease until liver transplantation or death.",[85],"Cirrhosis and Chronic Liver Disease",[87,88,89,90],"Cirrhosis","Decompensation","Acute-on-chronic liver failure","Death","2026-02-22",{"date":93,"type":94},"2026-02-27","ACTUAL",{"date":96,"type":94},"2022-08-12",{"date":98,"type":80},"2032-08-12",{"name":5,"class":6},3]