[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100517993":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":38,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":10,"enrollmentInfo":49,"targetDuration":52,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Retrospective Cohort",null,"Individuals in this group were previously seen by physicians at the Inherited Arrhythmia Clinic at University Hospital, London Health Sciences Centre, yet are no longer being actively followed here anymore. These patients will have their data retrospectively obtained annually, ten years into the past, to collect data on key variables providing insight on LVNC progression over time.",{"label":13,"type":10,"description":14,"interventionNames":10},"Prospective Cohort","Patients being actively followed up by physicians at the Inherited Arrhythmia Clinic will be approached either in person or via e-mail for consent and enrollment into this study. These patients will have their medical charts accessed annually to collect data on key variables providing insight on LVNC progression over time.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Dr. Habib Khan","CONTACT","519-663-3746","habib.khan@lhsc.on.ca",[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"London Health Sciences Centre - University Hospital","RECRUITING","London","Ontario","N6A5A5","Canada","CA",{"type":31,"coordinates":32},"Point",[33,34],-81.23304,42.98339,{"lat":34,"lon":33},[37],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},{"type":39,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100517993","predictors-of-risk-in-left-ventricular-non-compaction-100517993",false,"NCT06024759","Predictors of Risk in Left Ventricular Non-Compaction","Long Term Registry of Patients With Left Ventricular Non-Compaction and Predictors of Adverse Outcomes","Inclusion Criteria\n\nPatients must meet the following criteria in order to be included in the study.\n\n* Have a confirmed diagnosis of LVNC (between 2010-2020 for patients in the retrospective cohort only)\n* Be over 18 years of age\n\nExclusion Criteria\n\nPatients are ineligible to participate in this study if they do not meet one or more of the inclusion criterion or if they have any other cardiomyopathy aside from LVNC that is linked to a genetic mutation they carry.","ALL","18 Years",{"count":50,"type":51},500,"ESTIMATED","10 Years","OBSERVATIONAL","The goal of this study is to learn more about the risk factors associated with left ventricular non-compaction (LVNC) and the predictors of adverse outcomes associated with LVNC. The main questions this study aims to answer are as follows.\n\n* Are there any genetic mutations that impact the risk of LVNC patients developing ventricular arrhythmias?\n* Does LV myocardial strain increase risk stratification in the LVNC population with or without genetic mutations?\n* What are some of the determinants that cause LV dysfunction in LVNC?\n* What are other risk stratifiers (ex. premature ventricular contraction (PVC) burden on Holter, non-sustained ventricular tachycardia (NSVT) on stress test) that lead to an outcome of ICD implantation?\n\nParticipants will have their medical records accessed annually for a span of ten years, either prospectively or retrospectively depending on whether they are being actively followed by physicians at the Inherited Arrhythmia Clinic or not, to evaluate LVNC progression over time. This data will be stored in a large clinical registry with the London Heart Rhythm Program at the London Health Sciences Centre, University Hospital Campus.",[56],"Left Ventricular Noncompaction",[58,59],"LVNC","Left Ventricular Non-Compaction","2023-10-30",{"date":62,"type":63},"2023-11-01","ACTUAL",{"date":65,"type":63},"2023-09-01",{"date":67,"type":51},"2033-08-01",{"name":5,"class":6},1]