[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588355":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":58,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,12,15,18,21],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy Controls",null,"Healthy adult women who are planning pregnancy, currently pregnant, or postpartum.",{"label":13,"type":10,"description":14,"interventionNames":10},"Multiple sclerosis (MS)","Adult women diagnosed with multiple sclerosis (MS) who are planning pregnancy, currently pregnant, or postpartum.",{"label":16,"type":10,"description":17,"interventionNames":10},"Clinically isolated syndrome (CIS)","Adult women diagnosed with clinically isolated syndrome (CIS) who are planning pregnancy, currently pregnant, or postpartum.",{"label":19,"type":10,"description":20,"interventionNames":10},"Neuromyelitis optica spectrum disorder (NMOSD)","Adult women diagnosed with neuromyelitis optica spectrum disorder (NMOSD) who are planning pregnancy, currently pregnant, or postpartum.",{"label":22,"type":10,"description":23,"interventionNames":10},"Myasthenia gravis","Adult women diagnosed with myasthenia gravis who are planning pregnancy, currently pregnant, or postpartum.",[25],{"name":26,"affiliation":5,"role":27},"Riley Bove, MD, MSc","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Min Ji Kim Kim, BA","CONTACT","415-502-7209","minji.kim3@ucsf.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"University of California-San Francisco","RECRUITING","San Francisco","California","94158","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-122.41942,37.77493,{"lat":47,"lon":46},[50,52,56],{"name":51,"role":31,"phone":32,"phoneExt":10,"email":33},"Min Ji Kim",{"name":53,"role":31,"phone":54,"phoneExt":10,"email":55},"Ayushi Balan","415-514-8330","ayushi.balan@ucsf.edu",{"name":57,"role":27,"phone":10,"phoneExt":10,"email":10},"Riley Bove",{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100588355","pregnancy-registry-infants-serummilk-analysis-prisma-100588355",false,"NCT06940323","Pregnancy Registry, Infants, Serum\u002FMilk Analysis (PRISMA)","Pregnancy Registry, Infants, Serum\u002FMilk Analysis (PRISMA): Pregnancy Registry for Women With Chronic Conditions","Inclusion Criteria:\n\n* Pregnant or contemplating pregnancy\n* Female, aged 18 to 64 years\n* Diagnosis of one of the following conditions:\n* Clinically Isolated Syndrome (CIS) or Multiple Sclerosis (MS), based on the 2010 McDonald Criteria\n* Neuromyelitis Optica Spectrum Disorder (NMOSD)\n* Inflammatory Bowel Disease (IBD)\n* Rheumatoid Arthritis (RA)\n* Myasthenia Gravis\n* Lupus\n* Other chronic neurological conditions\n* Willing to provide biosamples and\u002For complete surveys at specified timepoints\n* Women without a chronic condition who are pregnant or contemplating pregnancy (as part of the control group)\n\nExclusion Criteria:\n\n\\- Unwillingness to provide informed consent",true,"FEMALE","18 Years","64 Years",{"count":72,"type":73},250,"ESTIMATED","OBSERVATIONAL","PRISMA, is a pregnancy registry study, focused on comprehensively collecting information about pregnancy in women with chronic neurological conditions from across the United States and internationally.\n\nDepending on their specific condition (MS, CIS, NMOSD, or other) and their specific treatment, participants will be asked to contribute to different aspects of the study. (1) The biosamples will be blood, breast milk, infant stool, maternal stool and vaginal swab samples, collected at specific time points. (2) The online surveys will be collected at specific time points. All study activities will be discussed with participants upon enrollment.\n\nBy collecting this information, the investigators hope to gain deeper insights into the relationship between pregnancy, the neurological condition, and maternal and infant health. For example, one of the sub-studies focuses on breast milk collection for women planning postpartum treatment with Ocrevus, Rituxan, Briumvi or Kesimpta.\n\nThis study is fully remote and all sample collection is optional, so participants can choose which types of samples they wish to provide. For blood draws, participants can schedule a home visit through ExamOne, making participation even more convenient.\n\nThe investigators aim to enroll women with chronic neurological conditions who are planning pregnancy, currently pregnant, or within one year postpartum.",[77,78,79,80],"Multiple Sclerosis","Clinically Isolated Syndrome","NMOSD","Myasthenia Gravis","2025-04-30",{"date":83,"type":84},"2025-05-04","ACTUAL",{"date":86,"type":84},"2017-03-21",{"date":88,"type":73},"2035-06",{"name":5,"class":6},1]