[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542187":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":10,"responsibleParty":36,"collaborators":10,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":40,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":52,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":10,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":10},{"fullName":5,"class":6},"Sunnybrook Health Sciences Centre","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Abnormal Placentation",null,"Women with a singleton or multiple pregnancy that are known or suspected of having abnormal placentation",[13],"Other: Biospecimen collection",{"label":15,"type":10,"description":16,"interventionNames":17},"Control","Women with a singleton or multiple pregnancy with a low-risk pregnancy.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Biospecimen collection","Biospecimens, including maternal blood and cervical mucus will be collected serially during pregnancy. After delivery tissue samples from the placenta and umbilical cord blood will be collected.",[9,15],[24],"Registry\u002Fdata collection from subject's medical records",[26],{"name":27,"affiliation":28,"role":29},"Sascha Drewlo, PhD","Sunnybrook Research Institute","PRINCIPAL_INVESTIGATOR",[31],{"name":27,"role":32,"phone":33,"phoneExt":34,"email":35},"CONTACT","1-416-480-6100","683853","sascha.drewlo@sri.utoronto.ca",{"type":37,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100542187","pregnancy-repository-100542187",false,"NCT06339606","Pregnancy Repository","Repository for Biospecimens From Pregnant Patients","PR","Inclusion Criteria:\n\n* Consenting pregnant adults (age 18-45 years) with known or suspected risk for abnormal placentation (Abnormal Placentation Group)\n* Consenting pregnant adults (age 18-45 years) with low-risk pregnancies (Control Group)\n* Singleton or multiple pregnancy\n* Ongoing clinical care at the participating sites, with delivery at the same institution.\n\nExclusion Criteria:\n\n* None","FEMALE","18 Years","45 Years",{"count":50,"type":51},7000,"ESTIMATED","9 Months","OBSERVATIONAL","An essential part of clinical research is the availability and accessibility of human biospecimens for the identification of biomarkers, new treatments and measurement of response to therapy. Proteins, RNA and DNA can be extracted and studied as well. This is a critical first step in performing many fundamental molecular biology experiments. A variety of biospecimens are utilized for research including but not limited to normal and malignant tissues, blood, and other body fluids.\n\nIn order to obtain high-quality biospecimens, they must be acquired serially, stored according to current standards, and matched with clinical information for maximum value. As such, the investigators would like to create a repository of biospecimens collected from pregnant patients who are seen at Mount Sinai Hospital and other research hospitals in Toronto. Mount Sinai provides personnel and infrastructure to serve the largest (7500 births\u002Fyear) and highest complex Maternity program in Ontario. Of the 7500 patients a year, at least 2500 are considered high risk pregnancies, where there's a possibility of preeclampsia, placenta accreta and a host of other complications. For this study, biological specimens - blood, cervical and placental samples - will be collected from these high-risk groups in order to better understand the causes of the underlying conditions.",[56,57,58,59,60],"Pregnancy Related","Fetal Growth Retardation","Placental Insufficiency","Preeclampsia","Cervix; Pregnancy","NOT_YET_RECRUITING","2024-04-22",{"date":64,"type":65},"2024-04-24","ACTUAL",{"date":67,"type":51},"2024-05-01",{"date":69,"type":51},"2031-04-30",{"name":5,"class":6}]