[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636308":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":24,"centralContacts":28,"locations":10,"responsibleParty":37,"collaborators":10,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":41,"sex":47,"minAge":48,"maxAge":10,"enrollmentInfo":49,"targetDuration":10,"studyType":52,"phases":10,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":10},{"fullName":5,"class":6},"Central Denmark Region","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with suspected non-ST-segment elevation acute coronary syndrome (NSTE-ACS)",null,"Adult patients assessed by participating emergency medical services (EMS) units with symptoms suggestive of acute coronary syndrome (ACS), in whom ST-segment elevation myocardial infarction (STEMI) is not identified on the prehospital electrocardiogram, and who are managed with planned transport to hospital for further evaluation. Patients undergo prehospital blood sampling for high-sensitivity cardiac troponin I (hs-TnI) measurement using a point-of-care device. Clinical management, triage, and transport decisions are not influenced by study participation or biomarker results.",[13],"Diagnostic Test: Prehospital high-sensitivity cardiac troponin I measurement",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Prehospital high-sensitivity cardiac troponin I measurement","Prehospital measurement of high-sensitivity cardiac troponin I (hs-TnI) using a point-of-care device during routine emergency medical services (EMS) assessment. Blood samples are analyzed according to manufacturer instructions and local procedures. The test is performed for research purposes only, and results are not available for clinical decision-making and do not influence patient management.",[9],[21,22,23],"hs-TnI","Point-of-care troponin","i-STAT hs-TnI",[25],{"name":26,"affiliation":5,"role":27},"Martin F Gude, MD, PhD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","+45 25 34 36 21","martgude@rm.dk",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Arne SR Jensen, Paramedic","+45 22 39 69 68","arjens@rm.dk",{"type":38,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100636308","prehospital-point-of-care-hs-troponin-i-for-rule-out-of-acute-myocardial-infarction-in-patients-without-st-segment-elevation-100636308",false,"NCT07563998","Prehospital Point-of-Care Hs-Troponin I for Rule-Out of Acute Myocardial Infarction in Patients Without ST-Segment Elevation","Prehospital Point-of-Care High-Sensitivity Troponin I for Rule-Out of Acute Myocardial Infarction in Suspected Non-ST-Segment Elevation Acute Coronary Syndrome: A Pilot Study","Pre-POCT TnI","Inclusion Criteria:\n\n* Age 18 years or older\n* Assessed by one of the participating EMS units equipped for POCT sampling\n* Presentation with symptoms suggestive of acute coronary syndrome\n* Planned transport to hospital for further evaluation\n\nExclusion Criteria:\n\n* ST-segment elevation on prehospital electrocardiogram\n* Clinical condition requiring immediate life-saving intervention precluding study procedures\n* Interhospital transport\n* Prior inclusion in the study within 30 days","ALL","18 Years",{"count":50,"type":51},500,"ESTIMATED","OBSERVATIONAL","People who call emergency medical services (EMS) with chest pain or other possible heart-related symptoms are often taken to hospital for further testing. However, only a small proportion of these patients are ultimately diagnosed with a serious heart condition such as a heart attack. This means that many patients undergo hospital transport and evaluation even though their risk is low.\n\nIn hospitals, a blood test called high-sensitivity cardiac troponin is commonly used to help diagnose or rule out heart attacks. It is not yet well established whether this type of test can be used safely and effectively earlier, in the prehospital setting.\n\nThis study will investigate whether it is feasible to measure high-sensitivity troponin in the ambulance and how well the test can identify patients at low risk of serious heart conditions. A small blood sample will be taken as part of routine care and analyzed using a portable device. The test result will not be used to guide treatment or decisions during the study.\n\nThe study will assess how well the test predicts heart-related events within 30 days and how practical it is to perform the test in real-life emergency settings. The results may help guide future research on how to improve early assessment and decision-making for patients with suspected heart disease.",[55,56],"Myocardial Infarction (MI)","Acute Coronary Syndromes (ACS)",[58,59,60,61,62,63,64,65,66,67,68],"Prehospital","Emergency Medical Services","Point-of-Care Testing","POCT","High-Sensitivity Troponin I","Chest Pain","Non-ST Elevation","Diagnostic Accuracy","Risk Stratification","Major Adverse Cardiac Events","MACE","NOT_YET_RECRUITING","2026-04-26",{"date":72,"type":73},"2026-05-04","ACTUAL",{"date":75,"type":51},"2026-05-15",{"date":77,"type":51},"2027-06-30",{"name":5,"class":6}]