[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628418":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":33,"locations":44,"responsibleParty":54,"collaborators":38,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":38,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":38,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":38,"overallStatus":47,"whyStopped":38,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group Oral Clonidine (OC)","ACTIVE_COMPARATOR","This group of children will be premedicated with oral clonidine (4 mic\u002FKg) 60 minutes preoperatively in a sip of water.",[13],"Drug: Oral Clonidine (OC)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group Oral Ketamine (OK)","This group of children will be premedicated with oral Ketamine (10 mg\u002FKg) 60 minutes preoperatively in a sip of water.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Oral Clonidine (OC)","compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower abdominal day-case surgery.",[9,15],[25],"Oral Ketamine (OK)",[27,30],{"name":28,"affiliation":5,"role":29},"Nevine M Gouda, Professor","STUDY_CHAIR",{"name":31,"affiliation":5,"role":32},"Sherif M Soaida, Assistant Professor","STUDY_DIRECTOR",[34,40],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},"Omnia Y Kamel, Doctorate degree","CONTACT","01270130326",null,"omniayehiakamel90@gmail.com",{"name":41,"role":36,"phone":42,"phoneExt":38,"email":43},"Ahmed O Mohamed, Master","01014429299","ahmedomoh630@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":38,"country":50,"countryCode":51,"cosmosGeoPoint":38,"geoPoint":38,"contacts":52},"Faculty of Medicine, Cairo University","RECRUITING","Cairo","Giza Governorate","Egypt","EG",[53],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"PRINCIPAL_INVESTIGATOR","Omnia Yahia El Sayed Kamel","Lecturer of anesthesiology and surgical ICU and pain management","100628418","premedication-in-children-a-clinical-trial-comparing-oral-ketamine-and-oral-clonidine-with-respect-to-sedation-level-and-opioid-consumption-in-pediatrics-undergoing-elective-lower-abdominal-day-case-surgery-100628418",false,"NCT07461376","Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.","Inclusion Criteria:\n\n* Children aged between 3 to 12 years old of both sexes undergoing elective lower abdominal day-case surgery such as: oblique inguinal herniorrhaphy, hypospadias correction and circumcision.\n* ASA I and II\n\nExclusion Criteria:\n\n* Parents refusal.\n* ASA risk score \\>II\n* Heart, lung, neurological, or central nervous system disorders (hypotension, hypovolemia, severe bradyarrhythmia, atrioventricular block II or III, acute cerebrovascular events, impaired consciousness, respiratory disorders with hypoventilation, myasthenia gravis and central sleep apnea syndrome)\n* Allergy from the used drugs.",true,"ALL","3 Years","12 Years",{"count":69,"type":70},84,"ESTIMATED","INTERVENTIONAL",[73],"NA","Aim of the work Is to compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower abdominal day-case surgery.",[76,77,78],"Pediatric Sedation","Clonidine Sedation","Ketamine Sedation","2026-03-07",{"date":81,"type":82},"2026-03-10","ACTUAL",{"date":84,"type":82},"2025-04-15",{"date":86,"type":70},"2026-11-01",{"name":5,"class":6},1]