[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598916":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":45,"responsibleParty":59,"collaborators":62,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":25,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":25,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":94,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Women and Infants Hospital of Rhode Island","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"In-person genetic counseling","ACTIVE_COMPARATOR","Patients in this group will be scheduled for an in-person genetic counseling visit to discuss options for aneuploidy screening, carrier screening, and prenatal diagnosis. For Spanish-speaking patients the genetic counselors will use in-person interpreters.",[13],"Other: In-person genetic counseling",{"label":15,"type":16,"description":17,"interventionNames":18},"Prenatal Genetics Chatbot- Prenatal GENEie","EXPERIMENTAL","Patients in the intervention group will be assisted by research staff to download and interact with the chatbot Prenatal GENEie in their preferred language (English or Spanish) for a minimum of 30 minutes to learn about aneuploidy screening, carrier screening and prenatal diagnosis.",[19],"Other: Prenatal GENEie Chatbot",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Prenatal GENEie Chatbot","Patient Educational Phone Chatbot Application for Prenatal Genetics in English \\& Spanish",[15],null,{"type":6,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"Standard in-person genetic counseling for prenatal genetics education",[9],[30],{"name":31,"affiliation":32,"role":33},"Method Tuuli, MD","Women & Infants Hospital in Providence RI","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Melissa L Russo, MD","CONTACT","2022360080","mlrusso@wihri.org",{"name":41,"role":37,"phone":42,"phoneExt":43,"email":44},"Sayda D Moran Cordon, BA","(401) 274-1122","42848","smorancordon@wihri.org",[46],{"facility":47,"status":25,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":25},"Women & Infants Hospital of Rhode Island","Providence","Rhode Island","02905","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-71.41283,41.82399,{"lat":57,"lon":56},{"type":33,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Melissa Russo","Assistant Professor, Maternal Fetal-Medicine & Genetics",[63],{"name":64,"class":65},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100598916","prenatal-genetics-chatbot-trial-prenatal-geneie-100598916",false,"NCT07077707","Prenatal Genetics Chatbot Trial: Prenatal GENEie","A Randomized Trial of Chatbot for Prenatal Genetic Counseling","Inclusion Criteria:\n\n* English or Spanish speaking with ability to read and write\n* Gestational age \\\u003C20 weeks\n* Access to smartphone or tablet (through personal use or study)\n\nExclusion Criteria:\n\n* Patients who have already had genetic counseling related to current pregnancy\n* h\u002Fo trisomy, major fetal anomaly. or aneuploidy in previous pregnancy\n* Parent with Robertsonian translocation\n* Twins, vanishing twin, multi-gestation pregnancy\n* Fetal anomaly noted in early pregnancy\n* In- vitro fertilization with pre-implantation genetic testing (PGT-A or PGT-M)","FEMALE","18 Years","55 Years",{"count":77,"type":78},1470,"ESTIMATED","INTERVENTIONAL",[81],"NA","During pregnancy, all pregnant people are offered tests to look for genetic conditions in the baby. However, there isn't a standard way of giving this information to patients. Doctors have a lot of things to discuss during the first prenatal visit and don't always have time to explain genetics in detail. Also, not everyone has access to genetic counselors. Prenatal genetics can be confusing, especially for people who haven't had a lot of formal education or who speak languages other than English. There might be misunderstandings about what these tests can find and what their benefits or risks are for these tests.\n\nMobile apps, like chatbots, could be a helpful way to give information about prenatal genetics. Almost everyone has a cell phone, and a chatbot can let people learn at their own speed and whenever they want.\n\nThe goal of this study is to see if a chatbot app Prenatal GENEie can teach pregnant women about prenatal genetics, and compare the chatbot to talking with a genetic counselor in person. The study wants to answer these main questions:\n\n* Does the Prenatal GENEie help pregnant patients learn about prenatal genetics the same way as a meeting with a genetic counselor?\n* Can the Prenatal GENEie and in-person counseling both help people make decisions about whether they want prenatal genetic testing?\n\nThe researchers will compare the chatbot Prenatal GENEie with in-person counseling to see if the chatbot teaches people about prenatal genetics in a similar way.\n\nParticipants will:\n\n* Take a test to check what they already know about prenatal genetics prior to the intervention\n* Use the chatbot or have an in-person meeting with a genetic counselor\n* Take a test after using the chatbot or meeting with a counselor to see how much their knowledge has improved\n* Fill out a survey about how comfortable they feel with their decision to do or not do prenatal genetic testing",[84],"Genetic Counseling",[86,87,88,89,90,91,92,93],"prenatal genetics","prenatal testing","mobile application","chatbot","patient education","aneuploidy","decisional conflict","genetics health literacy","NOT_YET_RECRUITING","2025-07-22",{"date":97,"type":98},"2025-07-28","ACTUAL",{"date":100,"type":78},"2026-01-01",{"date":102,"type":78},"2029-03-31",{"name":5,"class":6},1]