[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626749":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":26,"responsibleParty":39,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Istanbul Medipol University Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Low Anxiety Group",null,"Participants with STAI-I score ≤36 undergoing bimaxillary orthognathic surgery.",{"label":13,"type":10,"description":14,"interventionNames":10},"High Anxiety Group","Participants with STAI-I score ≥46 undergoing bimaxillary orthognathic surgery.",[16],{"name":17,"affiliation":18,"role":19},"Tuba Develi, Dr","Medipol University","STUDY_CHAIR",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Merve Gaye Akgök, DDS","CONTACT","+905064571329","merve.akgok@std.medipol.edu.tr",[27],{"facility":5,"status":28,"city":29,"state":10,"zip":10,"country":30,"countryCode":10,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"RECRUITING","Istanbul","Turkey (Türkiye)",{"type":32,"coordinates":33},"Point",[34,35],28.94966,41.01384,{"lat":35,"lon":34},[38],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Merve Gaye Akgök","PhD student, DDS","100626749","preoperative-anxiety-and-its-impact-on-intraoperative-hemodynamics-and-postoperative-pain-edema-and-trismus-in-orthognathic-surgery-100626749",false,"NCT07439679","Preoperative Anxiety and Its Impact on Intraoperative Hemodynamics and Postoperative Pain, Edema, and Trismus in Orthognathic Surgery","The Effect of Preoperative Anxiety Levels on Intraoperative Hemodynamic Parameters and Postoperative Edema, Pain, and Trismus in Patients Undergoing Bimaxillary Orthognathic Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* ASA physical status I or II\n* Patients scheduled for bimaxillary orthognathic surgery (Le Fort I osteotomy and bilateral sagittal split ramus osteotomy)\n* Ability to understand and complete the STAI questionnaire\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Previous orthognathic surgery\n* History of maxillofacial trauma\n* History of radiotherapy or chemotherapy in the head and neck region\n* Presence of psychiatric disorders or current use of psychiatric medications\n* Chronic systemic disease affecting bone metabolism or wound healing\n* Active smoking or substance abuse\n* Pregnancy or lactation\n* Incomplete questionnaire responses\n* Inability to attend follow-up visits","ALL","18 Years",{"count":53,"type":54},45,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the relationship between preoperative anxiety and intraoperative hemodynamic changes, as well as postoperative pain and facial edema, in patients undergoing orthognathic surgery.\n\nOrthognathic surgery is a corrective jaw surgery performed to treat dentofacial deformities. Although the procedure improves functional and aesthetic outcomes, patients may experience significant anxiety before surgery. Elevated anxiety levels may influence physiological responses during the operation and may affect postoperative recovery.\n\nIn this study, preoperative anxiety levels will be evaluated using validated assessment scales prior to surgery. During the intraoperative period, hemodynamic parameters such as heart rate and blood pressure will be recorded. After surgery, postoperative pain and facial edema will be assessed using standardized clinical evaluation methods.\n\nThe objective of this research is to determine whether higher levels of preoperative anxiety are associated with changes in intraoperative hemodynamic stability and increased postoperative discomfort. The findings may contribute to improved perioperative management strategies and enhanced patient care in orthognathic surgery.",[58],"Dentofacial Deformities",[60,61,62],"orthognathic surgery","preoperative anxiety","facial edema","2026-02-26",{"date":65,"type":66},"2026-02-27","ACTUAL",{"date":68,"type":66},"2025-02-01",{"date":70,"type":54},"2026-04",{"name":5,"class":6},1]