[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634275":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":69,"collaborators":18,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":18,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":18,"enrollmentInfo":80,"targetDuration":18,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":18,"overallStatus":91,"whyStopped":18,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Comprehensive Geriatric Assessment (CGA) Group","EXPERIMENTAL","Subjects undergo Comprehensive Geriatric Assessment (CGA) assessing frailty, functional status, cognition, comorbidities, nutritional and mental health status using validated tools (Fried Criteria, Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Charlson Comorbidity Index, Mini Nutritional Assessment, Geriatric Depression Scale).\n\nSubjects receive targeted preoperative interventions (nutritional support, prehabilitation, medical optimization, psychosocial support).",[13],"Other: Comprehensive Geriatric Assessment (CGA)",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care Group","NO_INTERVENTION","Subjects receive standard preoperative care including anesthesia, surgical procedures, and postoperative management according to institutional protocols",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Comprehensive Geriatric Assessment (CGA)","The Comprehensive Geriatric Assessment (CGA) is conducted using a structured approach integrating validated tools into routine preoperative evaluation: frailty assessed by Fried Frailty Criteria; functional status by Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL); cognitive function by Mini-Mental State Examination (MMSE) or Montreal Cognitive Assessment (MoCA); comorbidity burden by Charlson Comorbidity Index; nutritional status by Mini Nutritional Assessment (MNA); psychological status by Geriatric Depression Scale (GDS). Based on CGA findings, participants may receive individualized preoperative interventions including nutritional optimization, physical prehabilitation, medical optimization, and psychosocial or educational support.",[9],[25],{"name":26,"affiliation":5,"role":27},"Felice Giuliante, MD","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Chiara Schipa, MD","CONTACT","+39 0630154386","chiara.schipa@policlinicogemelli.it",{"name":35,"role":31,"phone":18,"phoneExt":18,"email":36},"Simone Vani, Bsc","simone.vani@policlinicogemelli.it",[38],{"facility":5,"status":18,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Roma","RM","00168","Italy","IT",{"type":45,"coordinates":46},"Point",[47,48],11.10642,44.99364,{"lat":48,"lon":47},[51,52,53,55,57,59,61,63,65,67],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},{"name":26,"role":27,"phone":18,"phoneExt":18,"email":18},{"name":30,"role":54,"phone":18,"phoneExt":18,"email":18},"SUB_INVESTIGATOR",{"name":56,"role":54,"phone":18,"phoneExt":18,"email":18},"Francesco Ardito, MD, PhD",{"name":58,"role":54,"phone":18,"phoneExt":18,"email":18},"Tiziana Bove, MD",{"name":60,"role":54,"phone":18,"phoneExt":18,"email":18},"Paola Aceto, MD, PhD",{"name":62,"role":54,"phone":18,"phoneExt":18,"email":18},"Maria Vellone, MD, PhD",{"name":64,"role":54,"phone":18,"phoneExt":18,"email":18},"Laura Levantesi, MD",{"name":66,"role":54,"phone":18,"phoneExt":18,"email":18},"Flaminio Sessa, MD",{"name":68,"role":54,"phone":18,"phoneExt":18,"email":18},"Francesco Razionale, MD, PhD",{"type":70,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100634275","preoperative-oncogeriatric-assessment-in-patients-undergoing-hepatectomy-100634275",false,"NCT07537569","Preoperative Oncogeriatric Assessment in Patients Undergoing Hepatectomy","Impact of Preoperative Oncogeriatric Assessment in Elderly Patients Undergoing Surgery for Hepatectomy","Inclusion Criteria:\n\n* Patients aged ≥ 70 years\n* Diagnosed hepatic malignancies requiring hepatectomy\n* Eligible for curative surgery as determined by multidisciplinary team\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Ineligibility for surgery due to advanced disease or severe comorbidities\n* Severe cognitive impairment (MMSE score \\\u003C 18)\n* Refusal to participate","ALL","70 Years",{"count":81,"type":82},242,"ESTIMATED","INTERVENTIONAL",[85],"NA","This study aims to bridge the gap between geriatric medicine and surgical oncology. The findings will provide valuable insights into optimizing perioperative care for older adults, enhancing surgical safety, and improving long-term recovery trajectories, thereby supporting a more patient-centered, multidisciplinary approach in the management of elderly patients undergoing hepatectomy",[88,89,90],"Hepatic Malignancies","Comprehensive Geriatric Assessment","Hepatectomy","NOT_YET_RECRUITING","2026-04-16",{"date":94,"type":95},"2026-04-17","ACTUAL",{"date":97,"type":82},"2026-04",{"date":99,"type":82},"2029-09",{"name":5,"class":6},1]