[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614549":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":17,"locations":22,"responsibleParty":39,"collaborators":41,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":7,"enrollmentInfo":59,"targetDuration":7,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":7,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Hull University Teaching Hospitals NHS Trust","OTHER_GOV",null,[9],{"type":10,"name":11,"description":11,"armGroupLabels":7,"otherNames":7},"OTHER","Patient and carer panel using nominal group approach and thematic analysis",[13],{"name":14,"affiliation":15,"role":16},"Joe Cuthbert, MBBS MD","Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Cottingham Road, Kingston-Upon-Hull, HU6 7RX","PRINCIPAL_INVESTIGATOR",[18],{"name":14,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","+441482 875875","joe.cuthbert@hyms.ac.uk",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Cardiology","RECRUITING","Hull","Yorkshire","HU16 5JQ","United Kingdom","UK",{"type":32,"coordinates":33},"Point",[34,35],-0.33525,53.7446,{"lat":35,"lon":34},[38],{"name":14,"role":19,"phone":20,"phoneExt":7,"email":21},{"type":40,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[42,45,47],{"name":43,"class":44},"Hull York Medical School","UNKNOWN",{"name":46,"class":10},"University of Birmingham",{"name":48,"class":44},"Robertson Centre for Biostatistics University of Glasgow Glasgow G12 8QQ","100614549","preparatory-work-for-a-trial-of-adjuncts-to-diuretic-treatment-in-patients-hospitalised-with-heart-failure-addressing-uncertainties-and-building-consensus-100614549",false,"NCT07281040","Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus","Preparatory Work for a Multi-arm, Multi-stage Trial of Adjunctive Treatments in Patients Hospitalised With Heart Failure (Pre-MAMMOTH-HF)","Pre-MAMMOTH-HF","Inclusion Criteria:\n\n1. Recent hospitalisation with heart failure (\\\u003C6 months) or carer for a person with a recent hospitalisation with heart failure.\n2. Able to participate in online group discussions in English\n\nExclusion Criteria:\n\n1\\. Unable to participate in online group discussions in English","ALL","18 Years",{"count":60,"type":61},10,"ESTIMATED","OBSERVATIONAL","Aims and Objectives\n\n1. Choose which adjunctive therapies, at what dose, and for how long\n2. Choose the dose(s) of IV furosemide to be used as the comparator\n3. Choose primary and secondary outcomes\n4. Estimate recruitment and engage sites for a future trial\n\nWork package 2a methods overview\n\n1. An online survey of clinicians (doctors, nurses and pharmacists) assessing potential ability to recruit and the acceptability of each adjunct and willingness to support a trial.\n2. Evidence generated (survey and reviews) will be considered by an expert panel (N=20-25) including expert clinicians and allied health professionals who care for people with HF using a modified Delphi approach. The panel will make recommendations on all aspects of the trial design.\n3. A patient and carer panel of people with a recent hospitalisation (\\\u003C6 months) for HF will provide recommendations on trial endpoints. The patient-and-carer advisory group (PCAG) will also input into these discussions.",[65],"Heart Failure","2025-12-04",{"date":68,"type":69},"2025-12-15","ACTUAL",{"date":71,"type":69},"2025-07-02",{"date":73,"type":61},"2026-10-01",{"name":5,"class":6},1]