[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636502":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":32,"collaborators":10,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":10,"eligibilityCriteria":41,"healthyVolunteers":38,"sex":42,"minAge":43,"maxAge":10,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Knee Osteoarthritis Patients",null,"Adults aged 40 years and older diagnosed with knee osteoarthritis based on the American College of Rheumatology (ACR) criteria attending the Assiut University Trauma Hospital.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Esraa M.H Ibrahim","CONTACT","+201112969235","esraa.m.hosny@aun.edu.eg",[19],{"facility":20,"status":10,"city":21,"state":10,"zip":10,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Assiut University Trauma Hospital","Asyut","Egypt","EG",{"type":25,"coordinates":26},"Point",[27,28],31.18368,27.18096,{"lat":28,"lon":27},[31],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Esraa Mostafa Hosny Ibrahim","Assistant Lecturer","100636502","prevalence-of-sarcopenia-and-its-associated-factors-in-patients-with-knee-osteoarthritis-in-a-tertiary-care-hospital-in-upper-egypt-100636502",false,"NCT07566520","Prevalence of Sarcopenia and Its Associated Factors in Patients With Knee Osteoarthritis in a Tertiary Care Hospital in Upper Egypt","Inclusion Criteria:\n\n* Adults aged 40 years and older diagnosed with knee OA based on the American College of Rheumatology (ACR) criteria.\n* Patients who are willing to participate and provide informed written consent.Exclusion Criteria:\n* Inflammatory arthritis: patients with rheumatoid arthritis, gouty arthritis, or systemic lupus erythematosus (SLE) to avoid confusion with inflammatory muscle wasting.\n* Physical Limitations: amputees or those with severe physical deformities preventing gait speed tests or handgrip measurement.\n* Patients with cardiac pacemakers or implanted electronic devices (as these interfere with Bioelectrical Impedance Analysis (BIA)).\n* Severe Comorbidities: end-stage renal or hepatic disease, advanced malignancy or cachexia.\n* Severe neurological disorders (e.g., Parkinson's disease, Stroke with paralysis) that directly affect muscle mass and mobility.\n* Prolonged use of systemic corticosteroids (which cause secondary sarcopenia)","ALL","40 Years",{"count":45,"type":46},224,"ESTIMATED","OBSERVATIONAL","Osteoarthritis (OA) and sarcopenia are two highly prevalent, interconnected geriatric syndromes that often coexist, leading to a condition termed \"osteosarcopenia\". Globally, the pooled prevalence of sarcopenia in patients with knee OA is estimated at approximately 25.07%, significantly higher than in the general population.",[50,51],"Osteoarthritis","Sarcopenia","NOT_YET_RECRUITING","2026-04-27",{"date":55,"type":56},"2026-05-05","ACTUAL",{"date":58,"type":46},"2026-05",{"date":60,"type":46},"2027-07",{"name":5,"class":6},1]