[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562317":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":36,"locations":10,"responsibleParty":46,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"(TNF) inhibitors",null,"1- Patients taking biologic (infliximab) treatment",[13],"Drug: TNF inhibitors",{"label":15,"type":10,"description":16,"interventionNames":17},"conventional IBD medical Treatment","patients taking conventional IBD medical Treatment",[18],"Drug: conventional ibd medical treatment",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"DRUG","TNF inhibitors","tumour necrosis factor inhibitors approved as treatments for ulcerative colitis and\u002For Crohns disease",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"conventional ibd medical treatment","Conventional therapies for ulcerative colitis and Crohns disease (CD) include aminosalicylates, corticosteroids, thiopurines, methotrexate other than anti-tumor necrosis factor agents.",[15],[30,33],{"name":31,"affiliation":5,"role":32},"Salwa salaheldin elgendi, professor doctor","STUDY_DIRECTOR",{"name":34,"affiliation":5,"role":35},"hossam Mahmoud AbdulWahab, assistant professor","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},"Mohamed Nasr Mohamed, resident doctor","CONTACT","+20 115 608 3878","mohammednasr886@gmail.com",{"name":43,"role":39,"phone":44,"phoneExt":44,"email":45},"Salwa salaheldin ELgendi, professor doctor","+201005766155","salwaelgendi@aun.edu.eg",{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Mohamed Nasr","Mohamednasr","100562317","prevelance-of-axial-spondylosis-arthritis-in-inflammatory-bowel-disease-and-its-response-to-tumour-necrosis-factor-tnf-inhibitors-treatment-in-assiut-university-hospital-100562317",false,"NCT06601595","Prevelance of Axial Spondylosis Arthritis in Inflammatory Bowel Disease and Its RESPONSE to Tumour Necrosis Factor (TNF) Inhibitors Treatment in Assiut University Hospital","Spondyloarthropathy in Inflammatory Bowel Disease Patients and Evaluation of Its Response to TNF Inhibitors in Assiut University Hospital","Inclusion Criteria:IBD patients (ulcerative colitis , Crohn\\'s disease )on TNF inhibitors Data collected included SPA and IBD variables, demographics, concurrent medications, co-morbidities and autoimmune serology.\n\nThey fulfil criteria of axial SPA Clinical Criteria 12 Low back pain ≥ 3 months, improved by exercise and not relieved by rest Limitation of lumbar spine in sagittal and frontal planes Limitation of chest expansion (relative to normal values corrected for age and sex) Radiological Criteria Bilateral grade 2-4 sacroiliitis, or; Unilateral 3-4 sacroiliitis Assessment of disease activity of SPA 13 Patient fulfill criteria of IBD 14 Assessment of IBD activity (Esr , CRP ,Faecal calprotectin , CBC , albumin ,endoscopy, histopathology) Mayo score for U.C Crohn\\'s disease Activity index\n\nExclusion Criteria: Other autoimmune disease , DM, LCF ,CRF ,Malignancy , Mechanical low back pain, Fracture , Spondylolisthesis , Spine tumores , Kidney stones .\n\n\\-","ALL","18 Years","60 Years",{"count":61,"type":62},100,"ESTIMATED","OBSERVATIONAL","Prevelance of axial spondylosis arthritis in inflammatory bowel disease and its RESPONSE to tumour necrosis factor (TNF) inhibitors TREATMENT",[66,67,68],"Inflammatory Bowel Disease (IBD)","Spondylarthropathies","TNF-alpha Inhibitors","NOT_YET_RECRUITING","2024-09-15",{"date":72,"type":73},"2024-09-19","ACTUAL",{"date":75,"type":62},"2024-10",{"date":77,"type":62},"2026-03",{"name":48,"class":6}]