[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616279":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":50,"centralContacts":60,"locations":66,"responsibleParty":81,"collaborators":36,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":36,"eligibilityCriteria":90,"healthyVolunteers":86,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":36,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":104,"overallStatus":69,"whyStopped":36,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Medipol University","OTHER",[8,15,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group (CG)","ACTIVE_COMPARATOR","Whey protein supplementation will be provided. Vitamin and mineral supplementation will be administered. No resistance exercise will be performed. Participants will follow bariatric surgery nutrition guidelines and maintain their regular physical activities.\n\nA comparison will be made with the other groups as the control group.",[13,14],"Dietary Supplement: Whey protein supplement","Dietary Supplement: Vitamin and Mineral Supplementation",{"label":16,"type":17,"description":18,"interventionNames":19},"Whey Protein + Collagen + Exercise Group (WPCEG)","EXPERIMENTAL","Collagen-containing whey protein supplementation will be provided. Vitamin and mineral supplementation will be given. Resistance exercises will be performed. Participants will follow bariatric surgery nutrition guidelines and maintain their physical activities.\n\nThey will begin the resistance exercise program in the 4th week after surgery.",[13,20,14,21],"Dietary Supplement: Hydrolyzed Collagen Supplement","Behavioral: Resistance Exercise Program",{"label":23,"type":17,"description":24,"interventionNames":25},"Whey Protein + Collagen + Non-Exercise Group (WPCG)","Collagen-containing whey protein supplementation will be provided. Vitamin and mineral supplementation will be administered. No resistance exercises will be performed. Participants will follow bariatric surgery nutrition guidelines and maintain their physical activities.",[13,14],{"label":27,"type":17,"description":28,"interventionNames":29},"Whey Protein + Exercise Group (WPEG)","Whey protein supplementation will be provided. Vitamin and mineral supplementation will be given. Resistance exercises will be performed. Participants will follow bariatric surgery nutrition guidelines and maintain their physical activities.\n\nThey will begin the resistance exercise program in the 4th week after surgery.",[13,14,21],[31,37,41,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DIETARY_SUPPLEMENT","Whey protein supplement","Oral whey protein supplement provided daily according to bariatric surgery nutrition protocol.",[9,16,23,27],null,{"type":32,"name":38,"description":39,"armGroupLabels":40,"otherNames":36},"Hydrolyzed Collagen Supplement","Oral hydrolyzed collagen supplement provided daily in combination with whey protein.",[16],{"type":32,"name":42,"description":43,"armGroupLabels":44,"otherNames":36},"Vitamin and Mineral Supplementation","Routine vitamin and mineral supplementation according to bariatric surgery follow-up protocol.",[9,16,23,27],{"type":46,"name":47,"description":48,"armGroupLabels":49,"otherNames":36},"BEHAVIORAL","Resistance Exercise Program","Structured resistance exercise program initiated at postoperative week 4, supervised, 3 times per week.",[16,27],[51,55,58],{"name":52,"affiliation":53,"role":54},"Halit E Taşkın, Dr.","Cerrahpaşa Faculty of Medicine, General Surgery","PRINCIPAL_INVESTIGATOR",{"name":56,"affiliation":57,"role":54},"Nihal Z Erdem, PhD","Istanbul Medipol University, Nutrition and Dietetics",{"name":59,"affiliation":36,"role":54},"Bürke Köksalan, PhD",[61],{"name":62,"role":63,"phone":64,"phoneExt":36,"email":65},"Rüken A Samancı, Msc","CONTACT","+90 543 939 15 94","rasamanci@medipol.edu.tr",[67],{"facility":68,"status":69,"city":70,"state":71,"zip":36,"country":72,"countryCode":36,"cosmosGeoPoint":73,"geoPoint":78,"contacts":79},"Istanbul Medipol University","RECRUITING","Istanbul","Fatih","Turkey (Türkiye)",{"type":74,"coordinates":75},"Point",[76,77],28.94966,41.01384,{"lat":77,"lon":76},[80],{"name":62,"role":63,"phone":64,"phoneExt":36,"email":65},{"type":54,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Rüken Aslınur Samanci","Lecturer","100616279","preventing-muscle-loss-after-bariatric-surgery-protein-collagen-supplementation-and-resistance-exercise-100616279",false,"NCT07303543","Preventing Muscle Loss After Bariatric Surgery: Protein-Collagen Supplementation and Resistance Exercise","Preventing Muscle Loss in the Early Postoperative Period of Bariatric Surgery With a Combination of Whey Protein, Hydrolyzed Collagen, and Resistance Exercise: A Prospective, Randomized, Controlled Clinical Study","Inclusion Criteria:\n\n* Being between 20-50 years old\n* Body mass index; 35 ≤ BMI\\\u003C 60 kg\u002Fm2\n* Not being pregnant\n* Not being addicted to alcohol and drugs\n* Not having entered menopause\n* No exercise restrictions\n\nExclusion Criteria:\n\n* Having at least one of the following inflammatory bowel diseases, upper gastrointestinal bleeding, advanced psychiatric diseases, cancer, and kidney failure.\n* using statins\n* be pregnant\n* Being addicted to alcohol and drugs\n* to have entered menopause\n* Having exercise restrictions\n* Becoming a professional athlete\n* Having done more than 60 minutes of regular and structured exercise per week in the last year","ALL","20 Years","50 Years",{"count":95,"type":96},35,"ESTIMATED","INTERVENTIONAL",[99],"NA","The aim of this clinical trial is to investigate the effectiveness of collagen, considered a new approach to prevent muscle mass loss after bariatric surgery, and to demonstrate the relationship between this effect and exercise. The key questions it aims to answer are:\n\nDoes whey protein supplementation with collagen combined with resistance exercise prevent muscle mass loss after bariatric surgery? Do whey protein supplementation with collagen combined with resistance exercise affect fat mass after bariatric surgery?\n\nResearchers will compare collagen with whey protein.\n\nThe study groups and interventions to be implemented are summarized below:\n\nGroup 1: Control Group (CG; n: 10) Whey protein supplementation will be administered Vitamin and mineral supplementation will be administered No resistance exercise will be performed The participants will eat according to bariatric surgery nutrition guidelines and perform physical activities.\n\nGroup 2: Whey Protein + Collagen + Exercise Group (WPCEG; n: 10) Whey protein supplements with collagen will be given. Vitamin and mineral supplements will be given. Resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities.\n\nThey will begin a resistance exercise program 4 weeks after surgery.\n\nGroup 3: Whey Protein + Collagen + No Exercise Group (WPCG; n: 10) Whey protein supplements with collagen will be given. Vitamin and mineral supplements will be given. No resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities.\n\nGroup 4: Whey Protein + Exercise Group (WPEG; n: 10) Whey protein supplements will be given. Vitamin and mineral supplements will be given. Resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities.\n\nA resistance exercise program will begin at 4 weeks post-operatively.",[102,103],"Bariatric Surgery","Muscle Loss",[102,105,106,107,108],"Collagen","Resistance exercise","Whey protein","Muscle loss","2025-12-10",{"date":111,"type":112},"2025-12-26","ACTUAL",{"date":114,"type":112},"2022-08-02",{"date":116,"type":96},"2026-01-30",{"name":5,"class":6},1]