[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566163":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":72,"collaborators":74,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":25,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":25,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":25,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Oakland University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Progressive Ratio Training","EXPERIMENTAL","Participants in the progressive ratio training Arm will experience the novel reinstatement-mitigation tactic: Progressive Ratio Training (PRT).\n\nProgressive ratio training (PRT) is used to prevent recurrence of the proxy response when extinction errors occur. PRT involves providing a reinforcer for the proxy response on a geometric progressive ratio (PR) scale. The schedule requirement will increase for the target response each time a reinforcer is delivered. For example, once a reinforcer is delivered on the PR-2 schedule, the requirement will increase to a PR-4, then to a PR-8, -16,\n\n-32, etc.",[13],"Behavioral: Progressive Ratio Training (PRT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Standard of Care","Participants in the standard of care Arm will receive an analogue to the standard of care approach for problem behavior: differential reinforcement of alternative behavior (DRA) with extinction.\n\nIn DRA with extinction, the proxy for problem behavior will cease to produce reinforcement while the proxy for communication behavior will produce reinforcement on a fixed-ratio 1 schedule of reinforcement.",[18],"Behavioral: Differential Reinforcement of Alternative (DRA) Behavior with Extinction",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Progressive Ratio Training (PRT)","Progressive ratio training (PRT) is used to prevent recurrence of the proxy response when extinction errors occur. PRT involves providing a reinforcer for the proxy response on a geometric progressive ratio (PR) scale. The schedule requirement will increase for the target response each time a reinforcer is delivered. For example, once a reinforcer is delivered on the PR-2 schedule, the requirement will increase to a PR-4, then to a PR-8, -16,\n\n-32, etc.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Differential Reinforcement of Alternative (DRA) Behavior with Extinction","In DRA with extinction, the proxy for problem behavior is placed on extinction and no longer produces reinforcement. The proxy for communication behavior produces reinforcement on a fixed-ratio 1 schedule of reinforcement.",[15],[31],{"name":32,"affiliation":5,"role":33},"Michael P Kranak, PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","248-370-4251","kranak@oakland.edu",[40,60],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Auburn University","RECRUITING","Auburn","Alabama","36849","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-85.48078,32.60986,{"lat":52,"lon":51},[55,59],{"name":56,"role":36,"phone":57,"phoneExt":25,"email":58},"John M Falligant, PhD","334-844-6483","jmf0031@auburn.edu",{"name":56,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":5,"status":42,"city":61,"state":62,"zip":63,"country":46,"countryCode":47,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Rochester","Michigan","48309",{"type":49,"coordinates":65},[66,67],-83.13382,42.68059,{"lat":67,"lon":66},[70,71],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":73,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[75],{"name":41,"class":6},"100566163","preventing-relapse-of-problem-behavior-through-behavioral-economics-a-translational-analysis-100566163",false,"NCT06651606","Preventing Relapse of Problem Behavior Through Behavioral Economics: A Translational Analysis","Using Behavioral Economics to Mitigate Relapse of Problem Behavior in an Intellectual and Developmental Disabilities Population","Inclusion Criteria:\n\n* Boys and girls from ages 6 to 21\n* Engage in problem behavior\n* Diagnosis of some type of intellectual and developmental disability\n\nExclusion Criteria:\n\n* Not meeting the inclusion criteria","ALL","6 Years","21 Years",{"count":87,"type":88},24,"ESTIMATED","INTERVENTIONAL",[91],"NA","The goal of this clinical trial is to compare a novel tactic for mitigating reinstatement compared to the current standard of care approach using a translational-treatment model. The main questions it aims to answer are:\n\n1. how well does progressive ratio training mitigate response-dependent reinstatement compared to the standard of care approach?\n2. how well does progressive ratio training mitigate response-independent reinstatement compared to the standard of care approach?",[94],"Problem Behavior","2025-08-15",{"date":97,"type":98},"2025-08-21","ACTUAL",{"date":100,"type":98},"2024-09-30",{"date":102,"type":88},"2026-09-10",{"name":5,"class":6},2]