[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590796":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":12,"centralContacts":23,"locations":33,"responsibleParty":50,"collaborators":12,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":12,"enrollmentInfo":62,"targetDuration":12,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":12,"overallStatus":36,"whyStopped":12,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Onassis Cardiac Surgery Centre","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","Standard of care",null,{"label":14,"type":6,"description":15,"interventionNames":16},"VEXUS","Goal-directed fluid therapy according to VEXUS measurements to minimize AKI",[17],"Device: VEXUS",[19],{"type":20,"name":14,"description":21,"armGroupLabels":22,"otherNames":12},"DEVICE","Goal-directed fluid and drug therapy according to VEXUS measurements to minimize AKI",[14],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":12,"email":28},"Stavros Dimopoulos, PhD, EDIC","CONTACT","00306973956974","stdimop@gmail.com",{"name":30,"role":26,"phone":31,"phoneExt":12,"email":32},"Konstantina Kolonia, MD, MSc","00306958261393","kon.kolonia@gmail.com",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Onassis Cardiac Surgery Center","RECRUITING","Athens","Kallithea","17674","Greece","GR",{"type":43,"coordinates":44},"Point",[45,46],23.72784,37.98376,{"lat":46,"lon":45},[49],{"name":25,"role":26,"phone":27,"phoneExt":12,"email":28},{"type":51,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100590796","prevention-and-treatment-of-aki-vexus-guided-post-cardiac-surgery-100590796",false,"NCT06972082","Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery","Prevention and Treatment of Acute Kidney Injury After Cardiac Surgery Guided by Combined Cardiac and Splanchnic Sonographic Assessment","VEXAKI","Inclusion Criteria:\n\n* Patients in the Cardiac Surgery ICU who develop acute kidney injury according to KDIGO criteria, within 48 hours of ICU admission after cardiac surgery\n* Elective and non-elective cardiac surgery.\n\nExclusion Criteria:\n\n* Patient refusal\n* Severe chronic renal failure (GFR\\\u003C15 mL\u002Fmin\u002Fm2 or on hemodialysis).\n* Critical preoperative condition (severe cardiogenic shock, resuscitated cardiac arrest, support with mechanical circulatory assist devices).\n* Liver cirrhosis or inferior vena cava obstruction.\n* Pregnancy.\n* Morbid obesity (BMI\\>40 kg\u002Fm2).\n* Delirium or other condition that prevents the performance of an ultrasound study.","ALL","18 Years",{"count":63,"type":64},304,"ESTIMATED","INTERVENTIONAL",[67],"NA","The main goal of this clinical trial is to learn if evaluation by ultrasound of venous congestion of liver and kidneys can guide treatment and prevent and treat acute kidney injury post cardiac surgery (CSA-AKI).\n\nParticipants will:\n\nBe evaluated by liver and kidney veins ultrasound (treatment group) or a placebo post CSA-AKI.\n\nFluid management for the treatment group will be based on a score that emerges from this evaluation (Venous Excess Ultrasound Score, VEXUS).\n\nKidney function will be daily monitored and followed-up for 7 days and until discharge.\n\nDaily fluid balance and laboratory examination will be performed. Data will be recorded and collected and a statistical analysis will provide the results that will show or not a probable superiority of this evaluation comparing to the usual care.",[70,71],"Acute Kidney Injury","Cardiac Surgery Associated - Acute Kidney Injury","2025-05-06",{"date":74,"type":75},"2025-05-14","ACTUAL",{"date":77,"type":75},"2023-06-29",{"date":79,"type":64},"2025-10",{"name":5,"class":6},1]