[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614781":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":30,"locations":37,"responsibleParty":54,"collaborators":11,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":11,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":11,"overallStatus":74,"whyStopped":11,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Group","SHAM_COMPARATOR",null,[13],"Behavioral: Standard of care",{"label":15,"type":16,"description":11,"interventionNames":17},"MetaNeb Group","EXPERIMENTAL",[18],"Device: MetaNeb Therapy",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","MetaNeb Therapy","Patients in the MetaNeb group receive at least 4 sessions of MetaNeb therapy on postoperative day 1 (each session includes cycles of CPEP and CHFO modes totaling 10 minutes).",[15],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"BEHAVIORAL","Standard of care","Standard postoperative care, including guidance on coughing and expectoration, turning and back percussion, and early mobilization (getting out of bed for physical activity).",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Minhui Dong","CONTACT","+86 02164041990","692959","dong.minhui@zs-hospital.sh.cn",[38],{"facility":39,"status":11,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Zhongshan Hospital Fudan University","Shanghai","Shanghai Municipality","200030","China","CN",{"type":46,"coordinates":47},"Point",[48,49],121.45806,31.22222,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":53,"phoneExt":35,"email":36},"+86 021 64041990",{"type":55,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100614781","prevention-and-treatment-of-early-postoperative-atelectasis-using-the-metaneb-system-in-patients-underwent-esophagectomy-100614781",false,"NCT07284056","Prevention and Treatment of Early Postoperative Atelectasis Using The MetaNeb System in Patients Underwent Esophagectomy","Inclusion Criteria:\n\n1. Age between 18 and 85 years.\n2. Patients who are scheduled for ICU admission after esophagectomy for esophageal cancer.\n\nExclusion Criteria:\n\n1. Presence of an artificial airway at the time of ICU admission.\n2. Planned ICU stay less than 24 hours.\n3. Patients with contraindications to the use of the MetaNeb® System, or those unable to cooperate due to organic or psychiatric conditions.","ALL","18 Years","85 Years",{"count":66,"type":67},178,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of this clinical trial is to evaluate whether the MetaNeb® System can effectively prevent and treat early postoperative atelectasis in adult patients admitted to ICU after esophagectomy for esophageal cancer.\n\nThe main question it aims to answer is: can the MetaNeb® system significantly reduce the lung ultrasound score (LUSS) indicating atelectasis on postoperative days 1 and 2? Participants will be randomly assigned to either the standard treatment or MetaNeb group, undergo lung ultrasound and electrical impedance tomography (EIT) assessments on postoperative days 1 and 2, receive at least 4 sessions of MetaNeb therapy on postoperative day 1 if in the intervention group, be monitored for oxygenation indices, ICU stay duration, incidence of mechanical ventilation, need for bronchoscopic intervention, and adverse events like pneumothorax.",[73],"Atelectases, Postoperative Pulmonary","NOT_YET_RECRUITING","2025-12-15",{"date":77,"type":78},"2025-12-16","ACTUAL",{"date":80,"type":67},"2026-01-01",{"date":82,"type":67},"2026-12-31",{"name":5,"class":6},1]