[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615807":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":18,"locations":18,"responsibleParty":19,"collaborators":23,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":18,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":18,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":57,"whyStopped":18,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":18},{"fullName":5,"class":6},"University Hospital Schleswig-Holstein","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Multidomain lifestyle intervention","EXPERIMENTAL","Multidomain lifestyle intervention including physical and cognitive training, sleep and nutrition counceling",[13],"Other: Multidomain lifestyle intervention",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":18},"Lifestyle intervention including physical and cognitive training, nutritional and sleep counseling",[9],null,{"type":20,"investigatorFullName":21,"investigatorTitle":22,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Eva Schaeffer","PD Dr. Eva Schäffer",[24,26,28,30],{"name":25,"class":6},"University Hospital, Bonn",{"name":27,"class":6},"University of Cologne",{"name":29,"class":6},"Philipps University Marburg",{"name":31,"class":6},"University of Kiel","100615807","prevention-in-pd-study-100615807",false,"NCT07297407","Prevention-in-PD-Study","PREVENTION-IN-PD - Development of a Multidomain Lifestyle Intervention Study for Prodromal and Clinical Parkinson's Disease","Inclusion Criteria:\n\n* All participants: ability to perform informed consent; age 30-85\n* RBD group: polysomnographic proven diagnosis of isolated REM sleep behavior disorder (iRBD)\n* PD group: early to moderate disease (Hoehn \\& Yahr stage 1-2.5), diagnosis according to the Movement Disorder Society diagnostic criteria for clinical Parkinson's Disease\n* Agreement to participate in group sessions and online meetings\n\nExclusion Criteria:\n\n* dementia (Mini Mental Score, MMSE \\\u003C 19 points) (MMSE is specifically chosen here to avoid too frequent repetitions of the MoCA, which is used as an outcome parameter for the interventional trial)\n* physical inability to perform exercise training or other trainings as judged by a physician\n* manifest (severe) depression (Beck Depression Inventory, BDI-II \\> 29 points)\n* participation in other interventional trials\n* other significant diseases of the central nervous system\n* Planned change in medication within the following 6 months","ALL","30 Years","85 Years",{"count":43,"type":44},99,"ESTIMATED","INTERVENTIONAL",[47],"NA","The goal of this clinical trial (feasibility study) is to learn if a multimodal lifestyle program can improve adherence to recommended lifestyle changes in people with REM Sleep Behavior Disroder (RBD) or Parkinson's disease (PD).\n\nThe main question it aims to answer is if individuals with RBD oder PD can follow a combined lifestyle program over six months Participants will take part in a six-month intervention program that includes: Physical training, Mediterranean diet counseling, Sleep counseling and cognitive training.\n\nThe program will be supported by psychoeducation, skills training, and personalization to make it practical and motivating.",[50],"Parkinson's Disease (PD)",[52,53,54,55,56],"lifestyle","exercise","nutrition","cognitive training","sleep","NOT_YET_RECRUITING","2025-12-16",{"date":60,"type":61},"2025-12-22","ACTUAL",{"date":63,"type":44},"2026-04-01",{"date":65,"type":44},"2027-09",{"name":5,"class":6}]