[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617048":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":25,"responsibleParty":31,"collaborators":25,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":25,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":25,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":59,"whyStopped":25,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":25},{"fullName":5,"class":6},"University Tunis El Manar","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Axillary Plexus Block with dexametasone","ACTIVE_COMPARATOR","In the cohort of patients undergoing hand surgery, participants are recruited from those who are willing to consent and participate in the study, and will be randomly recruited into intervention group. Intervention group will receive 30 ml of a 50\u002F50 mixture of isobaric bupivacaine 0.5% and lidocaine 1%, containing 8 mg of dexamethasone.",[13],"Drug: Dexamathsone 4mg\u002Fml associated with experimental arm",{"label":15,"type":16,"description":17,"interventionNames":18},"Axillary Plexus Block control","PLACEBO_COMPARATOR","In the cohort of patients undergoing hand surgery, participants are recruited from those who are willing to consent and participate in the study, and will be randomly recruited into placebo group. Control group will receive a 30 ml of a 50\u002F50 mixture of isobaric bupivacaine 0.5% and lidocaine 1%, containing 2 mL of saline solution.",[19],"Other: Saline",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Saline","2 ml saline solution are added to 30 ml of a 50\u002F50 mixture of isobaric bupivacaine 0.5% and lidocaine 1%",[15],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"DRUG","Dexamathsone 4mg\u002Fml associated with experimental arm","Intervention group will receive 30 ml of a 50\u002F50 mixture of isobaric bupivacaine 0.5% and lidocaine 1%, containing 8 mg of dexamethasone.",[9],{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Olfa kaabachi, MD","PROFESSOR","100617048","prevention-of-rebound-pain-after-axillary-block-100617048",false,"NCT07313553","Prevention of Rebound Pain After Axillary Block","The Effect of Perineural Dexamethasone on Preventing Rebound Pain After Axillary Plexus Block in Hand Surgery","Inclusion Criteria:\n\n* • Age between 18 and 75 years old.\n\n  * Patients are current for hand surgery under axillary plexus block.\n  * Patients classified ASA physical status I, II and III\n\nExclusion Criteria:\n\n* \\- Contraindication to regional anesthesia.\n* Patient's disapproval.\n* Impaired cognition.\n* Patients whose surgery must be done under general anesthesia (complex hand surgery or association of other)\n* Allergy to paracetamol, dexamethasone or opioids","ALL","18 Years","75 Years",{"count":46,"type":47},60,"ESTIMATED","INTERVENTIONAL",[50],"NA","This will be a single-center randomized double blind placebo control clinical trial. In the cohort of patients undergoing hand surgery under axillary nerve block, participants are recruited from those who are willing to consent and participate in the study, and will be randomly 1:1 divided into intervention group and placebo group.",[53,54],"Pain","Postoperative Care",[56,57,58],"axillary nerve block","dexamethesone","rebound pain","NOT_YET_RECRUITING","2025-12-17",{"date":62,"type":63},"2026-01-02","ACTUAL",{"date":65,"type":47},"2026-01-12",{"date":67,"type":47},"2026-09-30",{"name":5,"class":6}]