[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100398534":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":59,"collaborators":26,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":26,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NS Group","ACTIVE_COMPARATOR","NS Group includes patients who simply receive responsible segments fused (L4-S1).",[13],"Procedure: Responsible segments fused",{"label":15,"type":16,"description":17,"interventionNames":18},"LD Group","EXPERIMENTAL","LD Group includes patients who receive responsible segments fused (L4-S1) plus limited decompression at adjacent segment (L3\u002F4).",[19,13],"Procedure: Limited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Limited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis","In terms of limited decompression at the adjacent segment, partial laminotomy, flavectomy, and bilateral medial facetectomies up to the pedicle will be performed. Complete laminectomy and destroy of posterior ligament complex will be avoided.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Responsible segments fused","In terms of responsible segments fused, L4-5 and L5-S1 were fused using posterior lumbar interbody fusion (PLIF).",[15,9],[32],{"name":33,"affiliation":5,"role":34},"Wei Shi Li, Dr.","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Zhuo Ran Sun, Dr.","CONTACT","+8618610292513","puh3_szr@outlook.com",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Beijing","Beijing Municipality","100191","China","CN",{"type":50,"coordinates":51},"Point",[52,53],116.39723,39.9075,{"lat":53,"lon":52},[56],{"name":57,"role":38,"phone":26,"phoneExt":26,"email":58},"Da Zou, M.D.","zd_puth@163.com",{"type":60,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100398534","preventive-effect-of-limited-decompression-on-adjacent-segment-following-posterior-lumbar-interbody-fusion-100398534",false,"NCT04469387","Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion","Preventive Effect of Limited Decompression on Adjacent Segment With Pre-existing Spinal Canal Stenosis Following Posterior Lumbar Interbody Fusion: a Prospective Interventional Study","Inclusion Criteria:\n\n* A clear diagnosis of lumbar spinal stenosis, and surgical level of L4-S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression);\n* Patients have asymptomatic pre-existing spinal canal stenosis (cerebrospinal fluid occlusion grade=1) at adjacent segment.\n* Failed at least eight weeks conservative treatment;\n\nExclusion Criteria:\n\n* Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3\u002F4;\n* Preoperative sagittal and coronal imbalance of the spine;\n* Lumbar infection and\u002For tumor diseases;\n* A previous history of lumbar fusion surgery.","ALL","18 Years","80 Years",{"count":72,"type":73},200,"ESTIMATED","INTERVENTIONAL",[76],"NA","This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for degenerative disease are prospectively enrolled and followed. Patients enrolled in this study have asymptomatic pre-existing spinal canal stenosis at adjacent segment. This study will focus on the effects of preventative limited decompression at adjacent segment.",[79,80,81],"Degenerative Lumbar Spinal Stenosis","Degenerative Disc Disease","Degeneration Spine",[83,84,85,86],"Adjacent segment degeneration","Adjacent segment disease","Pre-existing degeneration","Limited decompression","2020-09-16",{"date":89,"type":90},"2020-09-18","ACTUAL",{"date":92,"type":90},"2020-09-01",{"date":94,"type":73},"2032-08-01",{"name":5,"class":6},1]