[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607471":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":38,"locations":44,"responsibleParty":60,"collaborators":30,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":30,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":30,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":47,"whyStopped":30,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Kasr El Aini Hospital","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group Lidocaine (L)","ACTIVE_COMPARATOR","Group L will receive 2ml of 2% lidocaine and 0.5ml of diluted adrenaline.",[13],"Procedure: Sphenopalatine Ganglion Block using 2% lidocaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Group Prilocaine (P)","EXPERIMENTAL","Group P will receive 2ml of 4% prilocaine and 0.5ml saline",[19],"Procedure: Sphenopalatine Ganglion Block",{"label":21,"type":16,"description":22,"interventionNames":23},"Group Prilocaine adrenaline (PA)","Group PA will receive 2ml of 4% prilocaine and 0.5ml of diluted adrenaline.",[19],[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Sphenopalatine Ganglion Block using 2% lidocaine","Sphenopalatine ganlion block with 2ml of 2% lidocaine and 0.5ml of diluted adrenaline after general anesthesia in patients undergoing enoscopic hypophysectomy.",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Sphenopalatine Ganglion Block","Sphenopalatine ganlion block with will receive 2ml of 4% prilocaine and 0.5ml saline after general anesthesia in patients undergoing enoscopic hypophysectomy.",[15],{"type":26,"name":32,"description":36,"armGroupLabels":37,"otherNames":30},"Sphenopalatine ganlion block with will receive 2ml of 4% prilocaine in addition to 0.5ml of diluted adrenaline. after general anesthesia in patients undergoing enoscopic hypophysectomy.",[21],[39],{"name":40,"role":41,"phone":42,"phoneExt":30,"email":43},"Rania Fahmy, Associate Professor","CONTACT","+201270820372","ransam98@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":30,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Kasr El Ainy","RECRUITING","Cairo","11956","Egypt","EG",{"type":53,"coordinates":54},"Point",[55,56],31.24967,30.06263,{"lat":56,"lon":55},[59],{"name":40,"role":41,"phone":42,"phoneExt":30,"email":43},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Rania Samir Fahmy","Associate professor","100607471","prilocaine-for-sphenopalatine-ganglion-block-in-endoscopic-hypophysectomy-100607471",false,"NCT07188987","Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy","Bilateral Sphenopalatine Ganglion Block Using Prilocaine Versus Lidocaine as Adjuvants to General Anesthesia During Endoscopic Hypophysectomy, Randomized Trial.","Inclusion Criteria:\n\n* Patients with pituitary adenoma undergoing endoscopic hypophysectomy.\n* ASA physical status I and II.\n* Age above 21, below 45 years.\n* Male or female\n\nExclusion Criteria:\n\n* Any patient below 21 years or above 45 years.\n* Patients suffering from any of the following conditions:\n\n  * Disturbed conscious level.\n  * Coagulation abnormalities.\n  * Poorly controlled blood pressure and\u002For heart rate.\n  * Increased intracranial tension.\n  * Liver and kidney disorders.\n* Patients on anticoagulants and\u002For NSAIDS (non-steroidal anti- inflammatory drugs\n* Patients addicted to drugs and\u002For alcohol.\n* Patients with disturbed conscious level at the end of the surgery, GCS \\>14","ALL","21 Years","45 Years",{"count":75,"type":76},54,"ESTIMATED","INTERVENTIONAL",[79],"NA","Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field.\n\nLocal anethetic infiltration and regional nerve blocks have been used to provide better analgesia, control blood pressure and improve surgical field.\n\nLimited studies evaluated shenopalatine ganglion block in pituitary adenoma excision with promising outcomes. The proposed study will compare the efficacy of two local anesthetics, prilocaine and lidocaine, for spenopalatine ganglion block in patients undergoing endoscopic pituitary adenoma excision. Evaluating the control of the intraoperative blood pressure and analgesic sparing are the main objectives of the proposed study.",[82],"Blood Pressure Control",[84,85,86,87],"Sphenopalatine ganglion block","Prilocaine","lidocaine","endoscopic hypophysectomy","2025-11-30",{"date":90,"type":91},"2025-12-05","ACTUAL",{"date":93,"type":76},"2025-12-01",{"date":95,"type":76},"2026-02",{"name":5,"class":6},1]