[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640713":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":37,"centralContacts":43,"locations":30,"responsibleParty":53,"collaborators":30,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":30,"enrollmentInfo":67,"targetDuration":30,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":85,"whyStopped":30,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":30},{"fullName":5,"class":6},"University of Geneva, Switzerland","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"3D-printed denture base and teeth","EXPERIMENTAL","Participants receive complete removable dental prostheses fabricated using a fully digital workflow with both the denture base and denture teeth produced by 3D printing.",[13],"Device: 3D-printed denture base and teeth",{"label":15,"type":16,"description":17,"interventionNames":18},"CAD\u002FCAM-Milled Denture Base with Milled Denture Teeth","ACTIVE_COMPARATOR","Complete dentures fabricated with CAD\u002FCAM-milled denture bases and CAD\u002FCAM-milled denture teeth",[19],"Device: CAD\u002FCAM-Milled Denture Base with Milled Denture Teeth",{"label":21,"type":16,"description":22,"interventionNames":23},"CAD\u002FCAM-Milled Denture Base with Prefabricated Denture Teeth","Participants receive complete removable dental prostheses fabricated using a digital workflow with CAD\u002FCAM-milled denture bases and conventionally manufactured prefabricated denture teeth. Conventional clinical reference.",[24],"Device: CAD\u002FCAM-Milled Denture Base with Prefabricated Denture Teeth",[26,31,34],{"type":27,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","Complete removable dental prostheses fabricated using a digital workflow with CAD\u002FCAM milling. Both the denture base and denture teeth are produced by subtractive manufacturing from pre-polymerized resin materials, including double cross-linked denture teeth, and assembled.",[15],null,{"type":27,"name":21,"description":32,"armGroupLabels":33,"otherNames":30},"Complete removable dental prostheses fabricated using a digital workflow with CAD\u002FCAM-milled denture bases combined with conventionally manufactured prefabricated denture teeth. The prefabricated teeth are selected and positioned digitally or manually and then bonded to the milled denture base.",[21],{"type":27,"name":9,"description":35,"armGroupLabels":36,"otherNames":30},"Description Complete removable dental prostheses fabricated using a fully digital workflow in which both the denture base and denture teeth are produced by 3D printing using light-curing resin materials. The prostheses are designed digitally and manufactured additively.",[9],[38,41],{"name":39,"affiliation":5,"role":40},"Najla Chebib, Dr med dent","PRINCIPAL_INVESTIGATOR",{"name":42,"affiliation":5,"role":40},"Alessio Casucci",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":30,"email":48},"Najla Chebib, PD Dr med dent","CONTACT","+41223794098","najla.chebib@unige.ch",{"name":50,"role":46,"phone":51,"phoneExt":30,"email":52},"Alessio Casucci, Dr Phd","+41223794060","Alessio.Casucci@unige.ch",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"SPONSOR_INVESTIGATOR","Najla Chebib","PD Dr","100640713","printow-occlusal-wear-of-denture-teeth-in-digitally-fabricated-complete-dentures-100640713",false,"NCT07585162","PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures","A Randomized, Double-Blind, Three-Arm Superiority Trial Comparing Occlusal Wear of 3D-Printed, CAD\u002FCAM-Milled, and Prefabricated Denture Teeth in Digitally Fabricated Complete Dentures in Edentulous Patients","Printow","Inclusion Criteria:\n\n* Written informed consent provided by the participant\n* Age ≥ 18 years\n* Fully edentulous maxilla and mandible requiring rehabilitation with new complete removable dental prostheses\n* Patients with or without mandibular implants (implant overdenture or conventional denture)\n* Clinical indication for fabrication of new maxillary and mandibular complete removable dental prostheses\n* Currently wearing complete dentures, or a maxillary denture combined with a mandibular denture or overdenture\n* Ability and willingness to attend all scheduled follow-up visits for the duration of the study\n\nExclusion Criteria:\n\n* Contraindications to the medical devices used, e.g. known hypersensitivity or allergy;\n* Known or suspected non-compliance, drug or alcohol abuse; Inability to follow the procedures of the investigation;\n* Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons;\n* Reported severe bruxism or clenching habits, identified through patient interview and clinical examination, including self-reported grinding or clenching, partner reports, morning jaw discomfort, and other signs of parafunctional activity;\n* Width of the edentulous maxilla \\>80 mm;\n* Width of the edentulous mandible \\>80 mm; Vertical prosthetic space \\\u003C38 mm (maxilla or mandible);\n* Depression: Geriatric Depression Scale \\>9;\n* Xerostomia: UFR ≤ 0.2ml\u002F2min;\n* Dementia: Clock-Drawing Test ≤5;\n* Active peri-implant disease or instability of the two mandibular implants at baseline when implants are present;\n* Presence of an implant-retained prosthesis in the maxilla;\n* Planned implant-related surgical intervention during the study period.","ALL","18 Years",{"count":68,"type":69},45,"ESTIMATED","INTERVENTIONAL",[72],"NA","This randomized controlled trial evaluates the occlusal wear of denture teeth fabricated using three digital workflows: 3D-printed denture teeth, CAD\u002FCAM-milled double cross-linked denture teeth, and prefabricated denture teeth. Occlusal wear will be assessed over 24 months using digital superimposition techniques. The study aims to determine whether 3D-printed denture teeth demonstrate superior wear resistance compared to CAD\u002FCAM-milled denture teeth.",[75,76],"Edentulism Complete","Edentulism",[76,78,79,80,81,82,83,84],"Complete dentures","Digital dentistry","3D printing","CAD\u002FCAM","Occlusal wear","Denture teeth","Randomized controlled trial","NOT_YET_RECRUITING","2026-05-08",{"date":88,"type":89},"2026-05-13","ACTUAL",{"date":91,"type":69},"2026-09-01",{"date":93,"type":69},"2032-12-30",{"name":55,"class":6}]