[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620380":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":29,"centralContacts":37,"locations":43,"responsibleParty":66,"collaborators":29,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":29,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":29,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":29,"overallStatus":46,"whyStopped":29,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A","EXPERIMENTAL","Patients will be receive probiotic mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.",[13],"Other: Probiotic mouthwash",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B","Patients will be treated with ethyl lauroyl arginate-containing mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.",[18],"Other: Ethyl lauroyl arginate mouthwash",{"label":20,"type":21,"description":22,"interventionNames":23},"Group C","ACTIVE_COMPARATOR","Patients will receive professional prophylaxis (scaling + polishing) at baseline and will use only regular toothpaste twice daily, with no adjunctive mouthwashes over 28 days.",[24],"Other: Professional prophylaxis (scaling + polishing)",[26,30,34],{"type":6,"name":27,"description":11,"armGroupLabels":28,"otherNames":29},"Probiotic mouthwash",[9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Ethyl lauroyl arginate mouthwash","Patients will be treated with ethyl lauroyl arginate mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.",[15],{"type":6,"name":35,"description":22,"armGroupLabels":36,"otherNames":29},"Professional prophylaxis (scaling + polishing)",[20],[38],{"name":39,"role":40,"phone":41,"phoneExt":29,"email":42},"Mohamed O Abdelrazik, MBBCH","CONTACT","00201017005990","mohamedghitany96@gmail.com",[44],{"facility":45,"status":46,"city":47,"state":29,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Al-Azhar University (Faculty of Dentistry)","RECRUITING","Cairo","11651","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],31.24967,30.06263,{"lat":55,"lon":54},[58,59,62,64],{"name":39,"role":40,"phone":41,"phoneExt":29,"email":42},{"name":60,"role":61,"phone":29,"phoneExt":29,"email":29},"Adel F Hussein, MD","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":29,"phoneExt":29,"email":29},"Ramy S Khairallah, MD",{"name":65,"role":61,"phone":29,"phoneExt":29,"email":29},"Alsayed E Mekky, MD",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Mohamed Osama Mohamed Abdelrazik","B.D.S, Faculty of Dental Medicine (Cairo-Boys), Al-Azhar University","100620380","probiotic-based-versus-ethyl-lauroyl-arginate-containing-mouthwashes-on-streptococcus-mutans-counts-dental-plaque-accumulation-and-salivary-ph-in-a-group-of-egyptian-school-children-100620380",false,"NCT07356869","Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children","Comparative Evaluation of Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Healthy Egyptian schoolchildren aged 6-12 years.\n* Good general health.\n* Mild to moderate dental plaque accumulation.\n* Parental\u002Fcaregiver willingness to provide consent\n\nExclusion Criteria:\n\n* Antibiotic or antimicrobial use within the last month.\n* Allergies to the mouthwash components.\n* Systemic diseases affecting oral health.\n* Orthodontic appliances or extensive dental restorations.","ALL","6 Years","12 Years",{"count":81,"type":82},66,"ESTIMATED","INTERVENTIONAL",[85],"NA","This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of Egyptian schoolchildren.",[88,89,90,91,92,93,94],"Probiotic","Ethyl Lauroyl Arginate","Mouthwashes","Streptococcus Mutans","Dental Plaque","Salivary pH","Children","2026-01-13",{"date":97,"type":98},"2026-01-21","ACTUAL",{"date":100,"type":98},"2025-08-15",{"date":102,"type":82},"2026-09-01",{"name":5,"class":6},1]