[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628503":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":38,"locations":44,"responsibleParty":62,"collaborators":31,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":31,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":31,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":31,"overallStatus":47,"whyStopped":31,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Wecare Probiotics Co., Ltd.","INDUSTRY",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic Group","EXPERIMENTAL","Taking 60 billion CFU of Lactobacillus plantarum Lp18 daily; Storage: Store in a cool, dry palce without sun expouse.",[13],"Dietary Supplement: Probiotic",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","Take 3g of maltodextrin daily; the product packaging is the same as that of probiotic products.",[19],"Dietary Supplement: Placebo",{"label":21,"type":10,"description":22,"interventionNames":23},"High-activity probiotic group","Taking 300 billion CFU of Lactobacillus plantarum Lp18 daily; Storage: Store in a cool, dry palce without sun expouse.",[24],"Dietary Supplement: High-activity probiotic probiotic",[26,32,35],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIETARY_SUPPLEMENT","Probiotic","The intervention period of this study will last for 8 weeks (56 days), during which each participant will attend three study visits scheduled at baseline (Week 0), Week 4, and Week 8.",[9],null,{"type":27,"name":33,"description":29,"armGroupLabels":34,"otherNames":31},"Placebo",[15],{"type":27,"name":36,"description":29,"armGroupLabels":37,"otherNames":31},"High-activity probiotic probiotic",[21],[39],{"name":40,"role":41,"phone":42,"phoneExt":31,"email":43},"Ying Jin","CONTACT","18336086291","1959643812@qq.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Suzhou Ninth People's Hospital","RECRUITING","Suzhou","Jiangsu","215000","China","CN",{"type":54,"coordinates":55},"Point",[56,57],120.59538,31.30408,{"lat":57,"lon":56},[60],{"name":61,"role":41,"phone":42,"phoneExt":31,"email":43},"Ying Jin, Doctor",{"type":63,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100628503","probiotic-improve-constipation-100628503",false,"NCT07462481","Probiotic Improve Constipation","A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Probiotics in Relieving Constipation in Adults","Inclusion Criteria:\n\n(1) Age 18-65 years; (2) Constipated patients (less than 3 bowel movements per week and\u002For Bristol Scale type 1 and 2); (3) Able to complete the study according to the trial protocol; (4) Patients who have signed the informed consent form; (5) Study participants (including male study participants) have no plans to have children within 14 days prior to screening and within 6 months after the end of the trial and voluntarily use effective contraception.\n\n\\-\n\nExclusion Criteria:\n\n1. Those who have taken a substance with a similar function to the test subject in a short period of time, affecting their judgment of the results;\n2. Patients who changed their diet during the study;\n3. Patients with severe allergies and immunodeficiency;\n4. Pregnant, breastfeeding, or women planning to become pregnant;\n5. Those with severe diseases of vital organs such as the cardiovascular system, lungs, liver, and kidneys, diabetes, thyroid disease, severe metabolic diseases, malignant tumors, or severe immune system diseases;\n6. Those who have used antibiotics in the past two weeks;\n7. Those with severe psychological or mental illnesses;\n8. Those who did not consume the test sample as required or did not follow up on time, resulting in the inability to determine the efficacy;\n9. Other study participants deemed unsuitable by the researchers. -",true,"ALL","18 Years","65 Years",{"count":76,"type":77},105,"ESTIMATED","INTERVENTIONAL",[80],"NA","To evaluate the efficacy and safety of probiotic as a food supplement in regulating bowel habits in patients with chronic constipation, and to compare it with placebo.",[83],"Constipation","2026-06-05",{"date":86,"type":87},"2026-06-09","ACTUAL",{"date":89,"type":77},"2026-06-10",{"date":91,"type":77},"2027-08-01",{"name":5,"class":6},1]