[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632351":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":31,"locations":39,"responsibleParty":57,"collaborators":23,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":23,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":41,"whyStopped":23,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Carleton University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic product (high dose)","EXPERIMENTAL","Probiotic product in capsule form to be consumed once per day over the course of the study.",[13],"Dietary Supplement: Probiotic Capsule",{"label":15,"type":10,"description":11,"interventionNames":16},"Probiotic product (low dose)",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"DIETARY_SUPPLEMENT","Probiotic Capsule","Jamieson 10 Billion Daily Maintenance Probiotic. The probiotic formulation contains Bifidobacterium animalis subsp. lactis (UABla-12), Lactobacillus paracasei (UALpc-04), Bifidobacterium breve (UABbr-11), Lactobacillus gasseri (UALg-05), Lactobacillus rhamnosus (UALr-06), Lactobacillus rhamnosus (UALr-18), Lactobacillus acidophilus (DDS-1), Lactobacillus plantarum (UALp-05), Bifidobacterium longum subsp. longum (UABl-14), Bifidobacterium bifidum (UABb-10), Lactobacillus casei (UALc-03), Lactobacillus reuteri (UALre-16), Lactococcus lactis (UALl-08), and Bifidobacterium longum subsp. infantis (UABi-13).",[9,15],null,[25,28],{"name":26,"affiliation":5,"role":27},"Kristin Connor, PhD","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":27},"Tim Van Mieghem, MD, PhD","MOUNT SINAI HOSPITAL",[32,36],{"name":26,"role":33,"phone":34,"phoneExt":23,"email":35},"CONTACT","613-520-2600","kristin.connor@carleton.ca",{"name":29,"role":33,"phone":37,"phoneExt":23,"email":38},"416-586-4800","tim.vanmieghem@sinaihealth.ca",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Ottawa","Ontario","K1S 5B6","Canada","CA",{"type":48,"coordinates":49},"Point",[50,51],-75.69812,45.41117,{"lat":51,"lon":50},[54,55,56],{"name":26,"role":33,"phone":34,"phoneExt":23,"email":35},{"name":29,"role":33,"phone":37,"phoneExt":23,"email":38},{"name":26,"role":27,"phone":23,"phoneExt":23,"email":23},{"type":58,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100632351","probiotic-research-on-safety-palatability-efficacy-and-receptivity-100632351",false,"NCT07512557","Probiotic Research On Safety, Palatability, Efficacy and Receptivity","Evaluating the Effectiveness and Feasibility of a Probiotic Intervention to Improve Nutrient Levels in Reproductive-Aged Women: A Pilot Study","PROSPER","Inclusion Criteria:\n\n* Non-pregnant and non-lactating\n* English speaking with the ability to give informed consent\n* 18-40 years of age (inclusive)\n* Women who are biologically female\n* Willing and able to agree to the requirements and lifestyle restrictions of this study\n* Able to understand and read the questionnaires in English and carry out all study-related procedures\n* Located in the greater Ottawa area and a resident of Ontario\n\nExclusion Criteria:\n\n* Individuals who are lactating, pregnant, or planning to become pregnant during the study\n* Individuals who are not maintaining adequate birth control measures\n* Adequate birth control measures include any option that will adequately prevent pregnancy including: contraceptives, lifestyle choices, complete abstinence, or as a result of other medical methods, procedures, or conditions\n* Have a known sensitivity, intolerability, or allergy to any of the study products or their excipients\n* Are using vitamin and mineral supplements containing B vitamins\n* Intake of a B-vitamin-containing micronutrient supplement or probiotic product in the previous 4 weeks\n* Expecting to change diet and exercise regimen in the next 4 weeks\n* Have planned surgery during the course of the study\n* Use of investigational product(s) in another research study within 30 days prior to the baseline visit or during the study duration\n* Taking probiotics during the study period\n* More than 2 alcoholic beverages per day throughout the duration of the study\n* Known medical history of specific conditions including: Gastrointestinal disorders: celiac disease, ulcerative colitis, and Crohn's disease; Gastric cancer and gastric polyps; Inflammatory bowel diseases; Helicobacter pylori infection; Gastrectomy, duodenal bypass, bariatric surgery",true,"FEMALE","18 Years","40 Years",{"count":72,"type":73},82,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this pilot study is to determine if taking a commercially available probiotic product can influence levels of vitamins B12, B6 and folate after a 4-week supplementation period in reproductive-aged women without any micronutrient deficiencies. The main question it aims to answer is:\n\n• Does a probiotic product influence blood folate, vitamin B12 and B6 levels in reproductive-aged women when it is taken regularly for 4 weeks?\n\nParticipants in this clinical trial will consume the probiotic product containing multiple probiotic strains regularly for 4 weeks. One group will consume one capsule per day at a particular dose, and the second group will consume two capsules per day at another dose. Participants will also have to:\n\n* Attend two in-person visits with a researcher: at enrolment (baseline), and endline (day 28\u002F4 weeks)\n* Provide a blood sample at baseline (day 0) and endline (day 28\u002F4 weeks)\n* Provide two stool samples (following each in-person visit)\n* Complete an online \"study diary\" every two weeks for 4 weeks (2 study diaries)\n* Complete two sets of online questionnaires (following each in-person visit)\n* Complete two sets of dietary assessments (following each in-person visit)",[79],"Probiotic Intervention",[81,82,83],"B vitamins","Reproductive-aged women","Probiotics","2026-04-01",{"date":86,"type":87},"2026-04-06","ACTUAL",{"date":89,"type":87},"2025-11-28",{"date":91,"type":73},"2026-07-30",{"name":5,"class":6},1]