[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593974":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":37,"responsibleParty":55,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Wecare Probiotics Co., Ltd.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic Group","EXPERIMENTAL","Take 30 billion CFU of complex probiotics every day (Lacticaseibacillus rhamnosus LRa05: Limosilactobacillus reuteri LR08= 1:1).",[13],"Dietary Supplement: Probiotic",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","Taking maltodextrin 3 g\u002Fday.",[19],"Dietary Supplement: Maltodextrin",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Probiotic","The trial period of this study is 3 months, and each patient will undergo 4 visits (in month 0, month 1, month 2, and month 3).",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Maltodextrin",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Fei Xu, Doctor","CONTACT","18623716648","＋86","xu.fei@haut.edu.cn",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"The First Affiliated Hospital of Zhengzhou University","RECRUITING","Zhengzhou","Henan","462000","China","CN",{"type":47,"coordinates":48},"Point",[49,50],113.64861,34.75778,{"lat":50,"lon":49},[53],{"name":32,"role":33,"phone":34,"phoneExt":54,"email":36},"+86",{"type":56,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100593974","probiotics-effects-on-hormones-body-and-mood-in-obese-women-100593974",false,"NCT07013409","Probiotics' Effects on Hormones, Body and Mood in Obese Women","Modulatory Effects of L. Rhamnosus LRa05 and L. Reuteri LR08 Probiotics on Hormone Metabolism, Body Composition, and Mood in Obese Women","Inclusion Criteria:\n\n* Age: 18 to 40 years old, female, BMI ≥ 25 kg\u002Fm2.\n* Be willing to receive follow-up during the intervention period.\n* Be willing to provide two blood, urine and fecal samples during the intervention period.\n* Be willing to take the compound probiotics by oneself every day during the intervention period.\n* Have good hearing and be able to hear and understand all instructions during the intervention period.\n\nExclusion Criteria:\n\n* Suffering from digestive system diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease).\n* Suffering from severe neurological disorders (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, long-term coma - excluding general anesthesia).\n* Have received\u002Fare currently receiving treatment for the following mental illnesses: alcohol\u002Fdrug\u002Fsubstance abuse dependence, schizophrenia, psychosis, bipolar disorder.\n* Take medication for depression or low mood.\n* Suffering from internal organ failure (such as heart, liver or kidney failure, etc.).\n* Have received radiotherapy or chemotherapy in the past.\n* Have received general anesthesia surgery\u002Fprocedures within the past three years, or plan to receive general anesthesia procedures\u002Fsurgeries within the next three months during this trial.\n* Have suffered from hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past.",true,"FEMALE","18 Years","40 Years",{"count":69,"type":70},100,"ESTIMATED","INTERVENTIONAL",[73],"NA","To evaluate the regulatory effect of probiotics formula on visceral fat metabolism and sex hormone balance in obese women.",[76],"Obesity, Women","2025-09-01",{"date":79,"type":80},"2025-09-08","ACTUAL",{"date":82,"type":80},"2025-07-01",{"date":84,"type":70},"2025-12-10",{"name":5,"class":6},1]